A National Cancer Institute-designated Comprehensive Cancer Center

Make an appointment: 800-826-HOPE

Who We Are

Who We Are
City of Hope is a leading research and treatment center for cancer, diabetes and other life-threatening diseases. Our researchers discover treatments that revolutionize how patients across the nation battle their diseases. And our physicians, surgeons and expert staff give life-saving care with compassion and comprehensive support. City of Hope’s main hospital is located in Duarte, Calif., northeast of Los Angeles, with clinics in Antelope Valley, Palm Springs, Pasadena, Santa Clarita and South Pasadena.  Since its beginnings more than a century ago, City of Hope has touched the lives of countless individuals facing the challenge of disease and has given them hope.
Translating research into life-saving treatments today

City of Hope is focused on rapidly transforming scientific discoveries into better treatments and prevention strategies for cancer, diabetes and other diseases. Its mission is to shorten the time from initial research idea to approval of new treatments in order to quickly bring cures to patients. Designated as a Comprehensive Cancer Center by the National Cancer Institute, City of Hope is also a founding member of the National Comprehensive Cancer Network.
The Comprehensive Cancer Center encompasses both the Beckman Research Institute and City of Hope National Medical Center and also includes the Irell & Manella Graduate School of Biological Sciences. Major facilities include the City of Hope Helford Clinical Research Hospital and the Center for Biomedicine and Genetics, a manufacturing facility specializing in the production of pharmaceutical materials.

This facility is one of three at City of Hope dedicated to the manufacture of potential new therapies, enabling investigators to create promising treatments without the high cost and delays encountered by other research centers. These capabilities save years of development time and ensure that City of Hope can rapidly and efficiently translate discoveries into beneficial care. City of Hope holds more than 200 patents.
In a multidisciplinary, interactive environment, more than 200 physicians and scientists involved in basic, clinical, translational and prevention research collaborate to develop innovative therapies for cancer, diabetes and other diseases. Their work is a continuum, starting with explorations of the mechanisms of diseases and their progression, moving on to the development of new treatments and the testing of those treatments in clinical trials, and, finally, delivering the best in patient care. This work furthers the understanding of disease risk assessment and prevention.

Research conducted at City of Hope has led to recombinant DNA technology and the identification of monoclonal antibodies, which in turn led to the development of synthetic human insulin and four of the top-selling cancer drugs, including bevacizumab and rituximab (Avastin and Rituxan, both from Genentech). City of Hope is a pioneer in the fields of bone marrow transplantation and cancer genetics and a national leader in islet cell transplantation, which has the potential to reverse type 1 diabetes. Researchers are also investigating new connections between diabetes and cancer, because what we discover about one disease could hold clues to advances against the other.
City of Hope collaborates with colleagues around the world, participating in more than 500 projects with more than 400 institutions in 40 states and more than 30 countries.

Patient care with kindness and compassion
“There is no profit in curing the body if, in the process, we destroy the soul.”

Those words, spoken by Samuel H. Golter, one of our early leaders, is the credo that has guided City of Hope’s approach to patient care. We treat the whole person by providing not only the best medical care possible for our patients, but also by providing that care in an atmosphere of kindness and compassion.
At City of Hope, our survivorship rates exceed those for patients treated at other cancer programs that report to the Commission on Cancer. With 217 staffed beds, specialized nursing care and an exceptional nurse-to-patient ratio (1:2 in ICU units), City of Hope ranks 99th percentile for in-patient satisfaction. Our physicians are recognized as experts in their fields, with many ranked “top doctors” in local and national surveys. Our surgeons’ expertise in less-invasive robotic procedures can greatly reduce the time patients recovering from surgery spend in the hospital.
Our nurses and hospital staff are trained in the science of supportive care, and the Sheri & Les Biller Patient and Family Resource Center offers the most integrated array of support services in the country. Patient navigators, for instance, tailor services to match the needs of each patient and family, whether they need help dealing with pain, getting transportation to the medical center or overcoming other barriers.
City of Hope gives its patients and their loved ones the resources, education and support they need to better manage the challenges related to a serious illness. Our pain and palliative care specialists, psychiatrists, psychologists, social workers, spiritual care chaplains and child-life specialists work with each individual on his or her unique circumstance.
City of Hope offers long-term survivorship clinics for survivors of childhood and prostate cancers and is developing a clinic for breast cancer survivors.  These long-term follow-up services help ensure that our cancer survivors’ unique medical needs are being met, helping them thrive long after their battles are won.

Why Choose City of Hope?

Institutional distinctions
  • City of Hope is one of 41 comprehensive cancer centers, the highest designation bestowed by the National Cancer Institute for excellence in cancer treatment, research, prevention and education.
  • City of Hope is ranked as one of “America’s Best Hospitals” in cancer by U.S.News & World Report.
  • City of Hope maintains the No. 1 hematology, prostate cancer and breast cancer programs in California, based on the number of patients treated.
  • City of Hope was awarded more than $79.7 million in research grants during 2012 and received $224.6 million in revenues from patented technologies in the 2012 fiscal year.
  • City of Hope is a pioneer of patient-centered care and remains committed to its tradition of exceptional compassionate care for patients and families. Each day, we live out our credo: “There is no profit in curing the body if, in the process, we destroy the soul.”
  • City of Hope has earned the highest rating — 4 stars — from the nation’s leading charity watchdog, Charity Navigator, in eight consecutive evaluations. That puts us among the top 2 percent of the charities rated by the organization.
  • City of Hope is supported by a unique nationwide network of more than 20 industry groups and hundreds of fundraising chapters, all of which serve as valuable partners in advancing our mission.
A record of innovation
  • Numerous breakthrough cancer drugs, including Herceptin, Rituxan, Avastin and Erbitux, are based on technology pioneered by City of Hope and are saving lives worldwide.
  • Millions of people with diabetes benefit from synthetic human insulin, developed through research conducted at City of Hope.
  • A pioneer in bone marrow transplantation, City of Hope has performed more than 11,000 bone marrow and stem cell transplants and operates one of the largest, most successful programs of its kind in the world. For eight years in a row, our bone marrow transplant program has performed above expectations in one-year patient survival. We are the only program in the country to achieve these outcomes for eight straight years.
  • City of Hope was one of the first cancer centers in the country to adopt robotic prostate surgery, in 2003. Since then, surgeons at City of Hope have performed more than 6,000 robotic procedures for prostate cancer.
Speed, efficiency and collaboration
  • City of Hope has not one but three on-site manufacturing facilities that enable investigators to manufacture promising new therapies without the high cost and delays encountered by other research centers. These capabilities save years of development time and ensure that we can rapidly and efficiently translate discoveries into beneficial treatments.
  • City of Hope has more than 200 patents. At any given time, we have more than 30 investigational new drug applications. These numbers are exceptionally large for an organization of City of Hope’s size, reflecting our commitment to innovation and speeding treatments to patients.
  • A uniquely collaborative environment makes it easy for laboratory and clinical researchers at City of Hope to more quickly translate breakthroughs into therapies.
  • City of Hope’s scientists collaborate with colleagues around the world. We participate in more than 500 projects with more than 400 institutions in 40 states and more than 30 countries. No matter where you live, there is likely collaboration between City of Hope and a center near you.
Transforming the future of cancer care
  • City of Hope researchers are investigating ways to harness the body’s natural defenses to fight cancer, an approach known as “immunotherapy.” One approach aims to harvest from patients the immune system’s T cells and reprogram them to defeat lymphoma and brain cancer. Another approach strikes a dual blow — shutting off a gene that promotes cancer while stimulating the immune system to action — in an effort to fight lymphoma and melanoma as well as brain, ovarian and prostate cancers. Other studies are focused on engaging every stage of the immune response to fight off breast cancer.
  • In 2010, we were the first institution in the world to use neural stem cells as a targeted delivery mechanism to treat patients with glioma, an aggressive type of brain tumor.
  • We have 35 novel therapies in our drug pipeline.
  • City of Hope scientists studying “super foods” have found that compounds in blueberries have the ability to fight triple-negative breast cancer cells in the laboratory. This team is planning human clinical trials to test the compounds’ effect on breast cancer; they’re also researching the anti-cancer properties of other “super foods” such as mushrooms, pomegranates and grape seed extract.
  • City of Hope researchers are pursuing a high-tech form of targeted radiation therapy to ease side effects of bone marrow and stem cell transplants. This approach, tested here first, uses total marrow irradiation, or TMI, as a replacement for irradiating a patient’s whole body before transplant. Researchers hope this approach will reduce the impact on healthy tissue while allowing for higher doses of therapeutic radiation.
  • Because life after cancer treatment can present both physical and emotional challenges, City of Hope creates a bridge between treatment and ongoing support. The Center for Cancer Survivorship provides specialized follow-up care and education for survivors of pediatric, prostate and breast cancers. The research that results from this program is helping physicians understand the long-term effects of cancer and its treatment — influencing how care is delivered today.
  • The Sheri & Les Biller Patient and Family Resource Center offers the most integrated array of support services in the country. One team can provide patients with navigation help, counseling, support groups and other resources that address their physical, emotional and spiritual needs. The research and tools developed through this approach will help patients everywhere.
Breakthroughs against diabetes
  • By investigating the molecular mechanisms of diabetes complications, City of Hope scientists are helping develop new treatments for them. They also are studying the use of blood stem cell transplantation to reboot the immune system in type 1 diabetes, an autoimmune disease.
  • City of Hope is a national leader in islet cell transplantation, which has the potential to reverse type 1 diabetes. In addition, we provide islet cells for research at other institutions throughout the U.S.
  • Researchers here are investigating new connections between diabetes and cancer, such as inflammation. What we discover about one disease could hold cures to advances against the other.
Toward a lasting cure for HIV/AIDS
  • City of Hope scientists pioneered the application of blood stem cell transplants to treat patients with HIV and AIDS-related lymphoma. Our researchers used a new form of gene therapy to achieve the first long-term persistence of anti-HIV genes in patients with AIDS-related lymphoma. This treatment ultimately may cure not only lymphoma, but also HIV/AIDS.
The philanthropic support that makes it all possible
  • Year after year, foundations, philanthropists, business leaders, global corporations, small businesses and hundreds of thousands of other caring individuals of all ages contribute generously to support the lifesaving work of City of Hope.
  • Celebrities supporting City of Hope through appearances, public service announcements and fundraising include the public faces of our Citizens of Hope awareness campaign: Kiefer Sutherland, Archie Panjabi, Taraji P. Henson, Josie Maran and Selena Gomez.
  • Many professional sports organizations have given their support to City of Hope, including the Los Angeles Dodgers, the Los Angeles Kings and Major League Soccer’s Chivas USA. City of Hope also was the 2009–10 official charity of the NFL on FOX. As the official charity of the Northern Trust Open, City of Hope has joined forces with Northern Trust and the PGA TOUR to bring hope to patients.

Our Mission

Our Mission:

City of Hope is transforming the future of health. Every day we turn science into practical benefit. We turn hope into reality. We accomplish this through exquisite care, innovative research and vital education focused on eliminating cancer and diabetes.
Our Values:

From day one, compassion has been woven into the heart and soul of our institution. Compassion for our patients, their families, and our team members.

We show compassion not only through treatment, but also through our philanthropy and advocacy, through our humanistic approach to research and care and through our day-to-day relationships with every individual.

We demonstrate compassion for our peers and colleagues by showing empathy and treating each other with dignity and respect.

We focus on turning great science into practical benefit as quickly as possible.

We tenaciously pursue new and better ways to improve the lives of people around the world. We are driven to provide new treatments for more people every day.

Our passion for serving others extends to our own people. We believe that providing opportunities to our own team members to engage and build community with colleagues helps them work more effectively.

We choose the right path, not the easy one.

We promote a “just culture” environment that requires each of us to do the right thing to ensure patient safety. We do what’s best for our patients and our community, every moment of every day.

Integrity guides us to passionately engage in our work, step up to every challenge and conduct our business with transparency. We hold ourselves accountable for following through with our commitments and doing the right thing.
Our reputation for scientific excellence stems from our determination to aggressively pursue new lines of inquiry.

We are lifelong learners committed to making pioneering discoveries and moving them forward for the benefit of patients and the scientific community worldwide. Our curiosity has fueled our innovation, creating life-changing moments and lifesaving breakthroughs, like developing the first synthetic human insulin and numerous cancer-fighting drugs.

Our commitment to advancing science while providing compassionate care has established us as the benchmark in fighting cancer, diabetes and other life-threatening diseases.

We strive for excellence in our processes and outcomes without compromising safety. We encourage every individual to use their best judgment, achieve synergies and make decisions that align with our mission, values and worldwide reputation for excellence.

We work as one team, united by a common purpose. We are a community of experts, combining the resources of cutting-edge scientific research, drug manufacturing, clinical care, graduate education, philanthropy and supportive care services.

Recognizing the value that bringing together diverse perspectives provides, we create an environment where new partnerships thrive, where barriers to freely sharing knowledge do not exist and where the right stakeholders are engaged from the beginning.

Our Diversity

City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patient’s needs, deliver compassionate care and continue the quest for a cure for life threatening diseases.
At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.
Robert Stone, J.D.
President and CEO
Employing a diverse workforce with individual talents and experiences allows us to better understand the needs of our patients, deliver compassionate care and continue our quest for a cure for life-threatening diseases. We believe we have a responsibility to build future health-care and research workforce that mirrors community we serve. We are committed to the education, training and development of young people to inspire passion about health care, medicine and science. Learn more about our recent efforts or watch this recent video of our Diversity Day celebration.
Stephanie Neuvirth
Chief Human Resources and Diversity Officer

Our History

Since its inception a century ago as a tuberculosis sanatorium started by the Jewish Consumptive Relief Association of California (JCRA), City of Hope has grown to become one of the most renowned medical institutions in the country, with a legacy of providing compassionate patient care and the best treatments available. In fact, City of Hope has pioneered many of the medical breakthroughs in the treatment of tuberculosis, cancer, diabetes, HIV-AIDS and other life-threatening diseases that are now considered standard medical practice.
The City of Hope story begins in 1913, when a poor young tailor, alone and in pain, collapses and dies from tuberculosis on a Los Angeles sidewalk. Saddened by the tragedy and spurred by compassion to help others in need, volunteers establish the JCRA and raise money to start a free, nonsectarian tuberculosis sanatorium. With almost $2,500 raised at a benefit concert at Temple Auditorium in downtown Los Angeles, the JCRA puts a down payment on 10 acres of sun-drenched land in Duarte, where they would establish the Los Angeles Sanatorium a year later. The sanatorium consists of two tents—one for patients and the other for a nurse. So begins a century-long journey that will place City of Hope at the forefront of the nation’s medical institutions.
Learn more about the City of Hope Story

Treatment Locations

Situated just northeast of Los Angeles, City of Hope combines the best science and the most innovative and highly compassionate patient care. Here, stretched across more than 100 acres in the City of Duarte, lushly landscaped gardens with more than 2,000 types of roses surround state-of-the-art facilities.
With its superior technologies, soaring atriums and dramatic mountain views, City of Hope’s Helford Clinical Research Hospital integrates the best of science and humanity in one state-of-the-art clinical research facility. Here, excellent clinical care and lifesaving research join forces as multidisciplinary teams of medical professionals pool their knowledge to bring promising therapies to patients quickly and safely.
A recognized leader in apheresis, donor matching and marrow transplants, City of Hope’s Michael Amini Transfusion Medicine Center is one of the largest hospital-based donor centers in the country. Here, in a safe and caring environment, families, friends and generous members of the community donate blood and platelets – 25,000 units of which our patients rely on each year.
Outpatient services for cancer patients, along with treatment for diabetes and other chronic illnesses, are provided in the Geri and Richard Brawerman Center for Ambulatory Care. In a facility adjacent to our hospital, we address the physical, emotional, and spiritual needs of the people in our care.
Designed to support the physical and emotional well-being of all women, the Rita Cooper Finkel and J. William Finkel Women’s Health Center focuses on the prevention, diagnosis and treatment of female diseases. The center’s warm colors and gently curved architecture create a soothing environment, while its physicians, nurses, and diagnosticians provide exemplary medical care.
Sometimes cancer cannot be cured, despite the best efforts. The ability to spend one's last days in a comforting home-like setting and to die with dignity is the inspiration behind City of Hope’s Village Hospice. In fully equipped apartments that open out to meditative gardens, patients and their families can be together – quietly, peacefully – close to their medical care team, yet in a place all their own.

City of Hope’s community practices extend the institution’s reach to more patients by bringing premier care to local communities in Central and Northern Los Angeles and Riverside Counties. For more patient information, including insurance, click here.
Located in Lancaster, Calif., City of Hope Antelope Valley provides surgical and diagnostic expertise for patients with cancer.
Whether you’re becoming a patient or referring one, City of Hope | Mission Hills offers superior expertise in the field of surgical oncology for breast cancer, colon cancer, pancreatic cancer, gynecologic cancers.
Located on Indian Canyon Dr. in Palm Springs, Calif., City of Hope physicians provide surgical and diagnostic expertise for patients with cancer.
City of Hope | Pasadena’s Urology and Urologic Oncology program offers state-of-the-art treatment options including robotic-assisted surgery which provides patients the benefits of faster recovery, decreased blood loss and minimal discomfort.
Located on the Henry Mayo Newhall Memorial Hospital campus in Santa Clarita, California,  City of Hope physicians provide surgical expertise for patients with general, thoracic, neurologic and urologic cancers.
City of Hope South Pasadena is a 22,000 square foot state-of-the-art outpatient cancer center which serves the San Gabriel Valley, San Fernando Valley and parts of greater Los Angeles.

Press Ganey Patient Satisfaction

City of Hope strives to give patients the best care. Everyone on our staff believes that patients and their families are their first priority. And we’re always trying to get even better.

Feedback is important to City of Hope. Patients help us improve our care. These two charts show how satisfied patients feel about our service.

Inpatient satisfaction at City of Hope is much higher than the national average. Outpatient satisfaction is greater than the average at other cancer centers.


City of Hope received both the Guardian of Excellence Award and the Beacon of Excellence Award in November, 2013. The Guardian of Excellence Award honors hospitals that have reached the 95th percentile for patient satisfaction. The award is given annually based on a single year of data. City of Hope received the former Summit Award the past four years, making this the fifth consecutive year City of Hope received this honor for its top performance.


The Beacon of Excellence Award, given to institutions that have maintained consistently high levels of excellence in patient satisfaction for three years and in employee engagement, physician engagement or clinical quality performance for two years. City of Hope was one of only 26 institutions in the nation recognized for patient satisfaction.
*C4QI = the Comprehensive Cancer Center Consortium for Quality Improvement, a group of 19 National Cancer Institute-designated comprehensive cancer centers.
About Press Ganey:
Press Ganey has been the industry's recognized leader in health care performance improvement. Press Ganey works with more than 10,000 health care organizations nationwide, including 50% of all U.S hospitals, to improve clinical and business outcomes. Press Ganey surveys inpatients and outpatients after discharge about a variety of topics related to their stay, including general satisfaction with the hospital’s services, speediness of admission, room cleanliness and staff courtesy. Scores are then compiled, analyzed and compared with those from other facilities of similar size.



Contact Us

For general information and all other inquiries, please call 626-256-HOPE (4673)
  • Refer a patient
    • Contact New Patient Services: 800-826-HOPE (4673).
    • Contact a patient in the hospital Call: 626-256-HOPE (4673).
Call the City of Hope job line: 626-301-8200, or search and apply online.
Join the fight against cancer, diabetes, HIV/AIDS and other life-threatening diseases by donating to City of Hope. Donate online or contact Donor Relations at 866-683-HOPE (4673) or donorrelations@coh.org.
  • For more giving opportunities, please click here.
  • For blood and platelet donations, call 626-471-7171 or click here for more information.
Find out more about the research and researchers at the City of Hope Comprehensive Cancer Center and the renowned Beckman Research Institute.
Request an interview with a physician or scientist (press inquiries only). Call 800-888-5323 or email Media Relations media@coh.org.
City of Hope respects your personal privacy and is committed to protecting it. It is not necessary to reveal your identity or any personal information to visit.
Welcome to City of Hope
City of Hope is a new model of cancer center, focused on rapidly transforming scientific discoveries into better treatments and better prevention strategies for cancer, diabetes, HIV/AIDS and other life-threatening diseases.

About City of Hope
City of Hope Locations

Learn about the talented individuals who are leading City of Hope towards the next horizon of treatments and cures for life-threatening diseases.

Learn more about
City of Hope's institutional distinctions, breakthrough innovations and collaborations.
  • For breast cancer survivors, a common worry is a recurrence of their cancer. Currently, these patients are screened with regular mammograms, but there’s no way to tell who is more likely to have a recurrence and who is fully cleared of her cancer. A new blood test – reported in Cancer Research, a journal of the...
  • Metastasis — the spreading of cancer cells from a primary tumor site to other parts of the body — generally leads to poorer outcomes for patients, so oncologists and researchers are constantly seeking new ways to detect and thwart this malicious process. Now City of Hope researchers may have identified a substa...
  • Deodorant, plastic bottles, grilled foods, artificial sweeteners, soy products … Do any of these products really cause cancer? With so many cancer myths and urban legends out there, why not ask the experts? They can debunk cancer myths while sharing cancer facts that matter, such as risk factors, preventi...
  • Cancer risk varies by ethnicity, as does the risk of cancer-related death. But the size of those differences can be surprising, highlighting the health disparities that exist among various ethnic groups in the United States. Both cancer incidence and death rates for men are highest among African-Americans, acco...
  • George Winston, known worldwide for his impressionistic, genre-defying music, considers music to be his first language, and admits he often stumbles over words – especially when he attempts languages other than English. There’s one German phrase he’s determined to perfect, however: danke schön. Winston thinks h...
  • Few decisions are more important than those involving health care, and few decisions can have such lasting impact, not only on oneself but on relatives and loved ones. Those choices, especially, should be made in advance – carefully, deliberately, free of pain and stress, and with much weighing of values and pr...
  • Using a card game to make decisions about health care, especially as those decisions relate to the end of life, would seem to be a poor idea. It isn’t. The GoWish Game makes those overwhelming, but all-important decisions not just easy, but natural. On each card of the 36-card deck is listed what seriously ill,...
  • Young adults and adolescents with cancer face unique challenges both during their treatment and afterward. Not only are therapies for children and older adults not always appropriate for them, they also must come to terms with the disease and treatment’s impact on their relationships, finances, school or ...
  • Breast cancer is the most common cancer, other than skin cancer, among women in the United States. It’s also the second-leading cause of cancer death, behind lung cancer. In the past several years, various task force recommendations and studies have questioned the benefits of broad screening guidelines fo...
  • Paternal age and the health effects it has on potential offspring have been the focus of many studies, but few have examined the effect parental age has on the risk of adult-onset hormone-related cancers (breast cancer, ovarian cancer and endometrial cancer). A team of City of Hope researchers, lead by Yani Lu,...
  • Hormone therapy, which is prescribed to women for relief of menopausal symptoms such hot flashes, night sweats and vaginal dryness, has recently seen a decline in popularity (and use) due to its link to an increased risk of breast and endometrial cancer. But City of Hope researchers have found that menopausal h...
  • Myeloproliferative neoplasms can’t be narrowed down to a single cancer, but they can be described by a defining characteristic: too many blood cells. The diseases bring with them a host of frustrating, potentially life-altering symptoms, and management of the diseases and their symptoms is crucial. An upcoming ...
  • More than 18,000 researchers, clinicians, advocates and other professionals will convene at the 105th American Association for Cancer Research (AACR) annual meeting taking place in San Diego from April 5 to 9. With more than 6,000 findings being presented over this five-day period, the amount of information can...
  • Cancer of the prostate is the No. 2 cancer killer of men, behind lung cancer, accounting for more than 29,000 deaths annually in this country. But because prostate cancer advances slowly, good prostate health and early detection can make all the difference. Many prostate cancer tumors don’t require immedi...
  • Despite advances made in detecting and treating nonsmall cell lung cancer, its prognosis remains grim. Even patients whose cancers are caught at their earliest stage have only a 50 percent chance of five-year survival. This poor prognosis is due in part to the cancer’s ability to resist treatment, renderi...