A National Cancer Institute-designated Comprehensive Cancer Center

Make an appointment: 800-826-HOPE

Who We Are

Who We Are
City of Hope is dedicated to making a difference in the lives of people with cancer, diabetes and other serious illnesses. Our mission is to transform the future of health care by turning science into a practical benefit, hope into reality. We accomplish this by providing outstanding care, conducting innovative research and offering vital education programs focused on eliminating these diseases.
Founded in 1913, City of Hope is one of only 41 comprehensive cancer centers in the nation, as designated by the National Cancer Institute. Our role as leaders in patient care, basic and clinical research, and the translation of science into tangible benefit is widely acknowledged.
Our community includes research associates, scientists, doctors, nurses, allied health professionals, graduate students, fundraising specialists, marketing professionals, volunteers and an extensive support staff. We are united by our desire to find cures, save lives and transform the future of health. Every discovery we make and every new treatment we create gives people the chance to live longer, better and more fully.
City of Hope continues to be a pioneer of patient centered care and remains committed to its tradition of exceptional care for patients, families and communities. Each day, we live out our credo:
"There is no profit in curing the body, if, in the process, we destroy the soul."

Why Choose City of Hope?

Institutional distinctions
  • City of Hope is one of 41 comprehensive cancer centers, the highest designation bestowed by the National Cancer Institute for excellence in cancer treatment, research, prevention and education.
  • City of Hope is ranked as one of “America’s Best Hospitals” in cancer by U.S.News & World Report.
  • City of Hope maintains the No. 1 hematology, prostate cancer and breast cancer programs in California, based on the number of patients treated.
  • City of Hope was awarded more than $79.7 million in research grants during 2012 and received $224.6 million in revenues from patented technologies in the 2012 fiscal year.
  • City of Hope is a pioneer of patient-centered care and remains committed to its tradition of exceptional compassionate care for patients and families. Each day, we live out our credo: “There is no profit in curing the body if, in the process, we destroy the soul.”
  • City of Hope has earned the highest rating — 4 stars — from the nation’s leading charity watchdog, Charity Navigator, in eight consecutive evaluations. That puts us among the top 2 percent of the charities rated by the organization.
  • City of Hope is supported by a unique nationwide network of more than 20 industry groups and hundreds of fundraising chapters, all of which serve as valuable partners in advancing our mission.
A record of innovation
  • Numerous breakthrough cancer drugs, including Herceptin, Rituxan, Avastin and Erbitux, are based on technology pioneered by City of Hope and are saving lives worldwide.
  • Millions of people with diabetes benefit from synthetic human insulin, developed through research conducted at City of Hope.
  • A pioneer in bone marrow transplantation, City of Hope has performed more than 11,000 bone marrow and stem cell transplants and operates one of the largest, most successful programs of its kind in the world. For eight years in a row, our bone marrow transplant program has performed above expectations in one-year patient survival. We are the only program in the country to achieve these outcomes for eight straight years.
  • City of Hope was one of the first cancer centers in the country to adopt robotic prostate surgery, in 2003. Since then, surgeons at City of Hope have performed more than 6,000 robotic procedures for prostate cancer.
Speed, efficiency and collaboration
  • City of Hope has not one but three on-site manufacturing facilities that enable investigators to manufacture promising new therapies without the high cost and delays encountered by other research centers. These capabilities save years of development time and ensure that we can rapidly and efficiently translate discoveries into beneficial treatments.
  • City of Hope has more than 200 patents. At any given time, we have more than 30 investigational new drug applications. These numbers are exceptionally large for an organization of City of Hope’s size, reflecting our commitment to innovation and speeding treatments to patients.
  • A uniquely collaborative environment makes it easy for laboratory and clinical researchers at City of Hope to more quickly translate breakthroughs into therapies.
  • City of Hope’s scientists collaborate with colleagues around the world. We participate in more than 500 projects with more than 400 institutions in 40 states and more than 30 countries. No matter where you live, there is likely collaboration between City of Hope and a center near you.
Transforming the future of cancer care
  • City of Hope researchers are investigating ways to harness the body’s natural defenses to fight cancer, an approach known as “immunotherapy.” One approach aims to harvest from patients the immune system’s T cells and reprogram them to defeat lymphoma and brain cancer. Another approach strikes a dual blow — shutting off a gene that promotes cancer while stimulating the immune system to action — in an effort to fight lymphoma and melanoma as well as brain, ovarian and prostate cancers. Other studies are focused on engaging every stage of the immune response to fight off breast cancer.
  • In 2010, we were the first institution in the world to use neural stem cells as a targeted delivery mechanism to treat patients with glioma, an aggressive type of brain tumor.
  • We have 35 novel therapies in our drug pipeline.
  • City of Hope scientists studying “super foods” have found that compounds in blueberries have the ability to fight triple-negative breast cancer cells in the laboratory. This team is planning human clinical trials to test the compounds’ effect on breast cancer; they’re also researching the anti-cancer properties of other “super foods” such as mushrooms, pomegranates and grape seed extract.
  • City of Hope researchers are pursuing a high-tech form of targeted radiation therapy to ease side effects of bone marrow and stem cell transplants. This approach, tested here first, uses total marrow irradiation, or TMI, as a replacement for irradiating a patient’s whole body before transplant. Researchers hope this approach will reduce the impact on healthy tissue while allowing for higher doses of therapeutic radiation.
  • Because life after cancer treatment can present both physical and emotional challenges, City of Hope creates a bridge between treatment and ongoing support. The Center for Cancer Survivorship provides specialized follow-up care and education for survivors of pediatric, prostate and breast cancers. The research that results from this program is helping physicians understand the long-term effects of cancer and its treatment — influencing how care is delivered today.
  • The Sheri & Les Biller Patient and Family Resource Center offers the most integrated array of support services in the country. One team can provide patients with navigation help, counseling, support groups and other resources that address their physical, emotional and spiritual needs. The research and tools developed through this approach will help patients everywhere.
Breakthroughs against diabetes
  • By investigating the molecular mechanisms of diabetes complications, City of Hope scientists are helping develop new treatments for them. They also are studying the use of blood stem cell transplantation to reboot the immune system in type 1 diabetes, an autoimmune disease.
  • City of Hope is a national leader in islet cell transplantation, which has the potential to reverse type 1 diabetes. In addition, we provide islet cells for research at other institutions throughout the U.S.
  • Researchers here are investigating new connections between diabetes and cancer, such as inflammation. What we discover about one disease could hold cures to advances against the other.
Toward a lasting cure for HIV/AIDS
  • City of Hope scientists pioneered the application of blood stem cell transplants to treat patients with HIV and AIDS-related lymphoma. Our researchers used a new form of gene therapy to achieve the first long-term persistence of anti-HIV genes in patients with AIDS-related lymphoma. This treatment ultimately may cure not only lymphoma, but also HIV/AIDS.
The philanthropic support that makes it all possible
  • Year after year, foundations, philanthropists, business leaders, global corporations, small businesses and hundreds of thousands of other caring individuals of all ages contribute generously to support the lifesaving work of City of Hope.
  • Celebrities supporting City of Hope through appearances, public service announcements and fundraising include the public faces of our Citizens of Hope awareness campaign: Kiefer Sutherland, Archie Panjabi, Taraji P. Henson, Josie Maran and Selena Gomez.
  • Many professional sports organizations have given their support to City of Hope, including the Los Angeles Dodgers, the Los Angeles Kings and Major League Soccer’s Chivas USA. City of Hope also was the 2009–10 official charity of the NFL on FOX. As the official charity of the Northern Trust Open, City of Hope has joined forces with Northern Trust and the PGA TOUR to bring hope to patients.

Our Mission

Our Mission:

City of Hope is transforming the future of health. Every day we turn science into practical benefit. We turn hope into reality. We accomplish this through exquisite care, innovative research and vital education focused on eliminating cancer and diabetes.
Our Values:

From day one, compassion has been woven into the heart and soul of our institution. Compassion for our patients, their families, and our team members.

We show compassion not only through treatment, but also through our philanthropy and advocacy, through our humanistic approach to research and care and through our day-to-day relationships with every individual.

We demonstrate compassion for our peers and colleagues by showing empathy and treating each other with dignity and respect.

We focus on turning great science into practical benefit as quickly as possible.

We tenaciously pursue new and better ways to improve the lives of people around the world. We are driven to provide new treatments for more people every day.

Our passion for serving others extends to our own people. We believe that providing opportunities to our own team members to engage and build community with colleagues helps them work more effectively.

We choose the right path, not the easy one.

We promote a “just culture” environment that requires each of us to do the right thing to ensure patient safety. We do what’s best for our patients and our community, every moment of every day.

Integrity guides us to passionately engage in our work, step up to every challenge and conduct our business with transparency. We hold ourselves accountable for following through with our commitments and doing the right thing.
Our reputation for scientific excellence stems from our determination to aggressively pursue new lines of inquiry.

We are lifelong learners committed to making pioneering discoveries and moving them forward for the benefit of patients and the scientific community worldwide. Our curiosity has fueled our innovation, creating life-changing moments and lifesaving breakthroughs, like developing the first synthetic human insulin and numerous cancer-fighting drugs.

Our commitment to advancing science while providing compassionate care has established us as the benchmark in fighting cancer, diabetes and other life-threatening diseases.

We strive for excellence in our processes and outcomes without compromising safety. We encourage every individual to use their best judgment, achieve synergies and make decisions that align with our mission, values and worldwide reputation for excellence.

We work as one team, united by a common purpose. We are a community of experts, combining the resources of cutting-edge scientific research, drug manufacturing, clinical care, graduate education, philanthropy and supportive care services.

Recognizing the value that bringing together diverse perspectives provides, we create an environment where new partnerships thrive, where barriers to freely sharing knowledge do not exist and where the right stakeholders are engaged from the beginning.

Our Diversity

At City of Hope, we strive to create an inclusive environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally.
Each day brings an opportunity to strengthen our work, leverage our unique perspectives and improve our patients' experiences by learning from others.
We invite you to learn more about our commitment to diversity and inclusion. Click here to download our brochure.

Our History

The City of Hope story began in 1913, when a group of volunteers, spurred by compassion to help those afflicted with tuberculosis, established the Jewish Consumptive Relief Association (JCRA) and raised money to start a free, nonsectarian tuberculosis sanatorium.
So was launched a century-long journey that would place City of Hope at the forefront of the nation’s leading medical and research institutions.

Today, City of Hope has been designated as a comprehensive cancer center, the highest recognition bestowed by the National Cancer Institute, and is a founding member of the National Comprehensive Cancer Network, with research and treatment protocols that advance care throughout the nation.
Learn more about the City of Hope Story


Located just northeast of Los Angeles, City of Hope bridges innovative science with compassionate patient care. Here, stretched across more than 100 acres in the City of Duarte, lushly landscaped gardens and open spaces surround our cutting edge medical and research facilities.
Medical Facilities at the Duarte Campus Include:

City of Hope’s community practices extend the institution’s reach to more patients by bringing premier care to local communities in Los Angeles and Riverside Counties.
Located in Lancaster, Calif., City of Hope | Antelope Valley provides a comprehensive range of surgical, treatment and diagnostic services for patients with cancer.
Working with local physicians, City of Hope provides Arcadia and its surrounding communities with unmatched cancer treatment and care.
Whether you’re becoming a patient or referring one, City of Hope | Mission Hills offers superior expertise in the field of surgical oncology for breast cancer, colon cancer, pancreatic cancer, gynecologic cancers.
Located on Indian Canyon Dr. in Palm Springs, Calif., City of Hope physicians provide surgical and diagnostic expertise for patients with cancer.
City of Hope | Pasadena’s Urology and Urologic Oncology program offers state-of-the-art treatment options including robotic-assisted surgery which provides patients the benefits of faster recovery, decreased blood loss and minimal discomfort.
Located on the Henry Mayo Newhall Memorial Hospital campus in Santa Clarita, California, City of Hope physicians provide surgical expertise for patients with general, thoracic, neurologic and urologic cancers.
City of Hope | South Pasadena is a 22,000 square foot state-of-the-art outpatient cancer center serving the San Gabriel and San Fernando valleys and the greater Los Angeles region.

Contact Us

For general information and inquiries, please call 626-256-HOPE (4673). You can also connect with us through social media.
  • Refer a patient - Call (800) 826-HOPE (4673) Monday through Friday from 7 a.m. to 8 p.m. and Saturday & Sunday from 9 a.m. to 6 p.m. to speak with a patient referral specialist.
Call the City of Hope job line: (626) 301-8200 or search and apply online.
Join the fight against cancer, diabetes, HIV/AIDS and other life-threatening diseases by donating to City of Hope. Donate online or contact Donor Relations at 866-683-HOPE (4673) or donorrelations@coh.org.
  • For more giving opportunities, please click here.
  • For blood and platelet donations, call (626) 471-7171 or click here for more information.

To request a press interview with a City of Hope expert or to schedule a time for a photo- or videoshoot, call (800) 888-5323 or email media@coh.org.
Find out more about the research and researchers at the City of Hope Comprehensive Cancer Center and the renowned Beckman Research Institute.
Welcome to City of Hope
City of Hope is a new model of cancer center, focused on rapidly transforming scientific discoveries into better treatments and better prevention strategies for cancer, diabetes, HIV/AIDS and other life-threatening diseases.

Virtual Tour of City of Hope
City of Hope Locations

Learn about the talented individuals who are leading City of Hope towards the next horizon of treatments and cures for life-threatening diseases.

Learn more about
City of Hope's institutional distinctions, breakthrough innovations and collaborations.
  • A common surgical device, often used for minimally invasive hysterectomies, may be riskier than previously thought because of its potential to spread several types of cancer, not just uterine cancer, a new study has found. One out of every 368 women treated with a power morcellator – a device that cuts the uter...
  • Skin cancer rates have been on the rise for years. On Tuesday, the U.S. surgeon general said: Enough. In issuing the first-ever Call to Action to Prevent Skin Cancer, acting Surgeon General Boris Lushniak described skin cancer as a “major public health problem” that requires action by all segments o...
  • Learn more about becoming a patient or getting a second opinion at City of Hope by visiting us online or by calling 800-826-HOPE (4673). City of Hope staff will explain what’s required for a consult at City of Hope and help you determine, before you come in, whether or not your insurance will pay for the ...
  • Counter-intuitive though it might seem, a prostate cancer diagnosis shouldn’t always lead to immediate prostate cancer treatment. Although prostate cancer is the second-leading cancer killer of men, behind lung cancer, and causes more than 29,000 deaths in the U.S. each year, in many cases, the tumors are...
  • Radiology is one of the cornerstones of any hospital. It is a key diagnostic branch of medicine essential for the initial diagnosis of many diseases and has an important role in monitoring a patient’s treatment and predicting outcome. Radiology is the specialty considered to be both the “eyes” and “ears” of med...
  • Donating blood and platelets saves lives. We all know this. Yet every summer, potential blood donors become distracted by vacations and schedule changes. As a result, blood donations fall dramatically across the nation, leaving hospitals frantically trying to bring in much-needed blood for their patients. Earli...
  • To be a great cancer hospital, you need a great oncology program. Just ask City of Hope – and Becker’s Hospital Review. The health care publishing industry stalwart, described as the “leading hospital magazine for hospital business news and analysis for hospital and health system executives,” recently selected ...
  • Diagnostic errors are far from uncommon. In fact, a recent study found that they affect about 12 million people, or 1 in 20 patients,  in the U.S. each year. With cancer, those errors in diagnosis can have a profound impact. A missed or delayed diagnosis can make the disease that much harder to treat, as the Ag...
  • Eleven years ago, lymphoma patient Christine Pechera began the long road toward a cancer-free life. She had been diagnosed with non-Hodgkin lymphoma and told by doctors elsewhere that her lifespan likely would be measured in months, not years. Refusing to give up, she came to City of Hope for a second opinion. ...
  • Brain surgery is not for the faint of heart. It takes courage, as well as curiosity and compassion. The truly great surgeons also have a desire to find new, and better ways, of healing the brain. Enter Behnam Badie, M.D., chief of neurosurgery at City of Hope. Now a pioneer in brain tumor treatment, Badie enter...
  • Elizabeth Budde, M.D., Ph.D., wants to encourage infighting. She aims to turn the immune system on itself — to the benefit of patients with acute myeloid leukemia, or AML. AML arises when abnormal white blood cells grow out of control, amassing in the bone marrow and interfering with normal blood cell developme...
  • Six, to date; more soon. Outpatient bone marrow transplants, that is. Finding new ways to deliver quality care with the greatest benefit is a priority for a patient-centered institution like City of Hope. For example, not every bone marrow transplant patient needs to check into the hospital for treatment. In fa...
  • The best measure of success in the fight against cancer is in lives saved and families intact, in extra days made special simply because they exist. Yuman Fong, M.D., chair of the Department of Surgery at City of Hope, understands what precedes that special awareness. When cancer strikes, one minute a person ma...
  • In cancer, expertise matters. So do survival rates, patient safety, patient services and many other factors. City of Hope understands this, as does U.S.News & World Report. The magazine’s 2014-2015 list of best hospitals for cancer once again includes City of Hope, ranking the institution 12 out of 900 elig...
  • At 29, Kommah McDowell was a successful young professional engaged to be married to her best friend. She worked in the financial services sector and kick-boxed to keep in shape and to relax. Then came the diagnosis of triple-negative inflammatory breast cancer, a rare and very aggressive form of breast cancer. ...