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Translational Research Laboratory Core

The Translational Research Laboratory Core at City of Hope is under the direct supervision of  Yen Yun, M.D., Ph.D., Dr. & Mrs. Allen Y. Chao Chair in Developmental Cancer Therapeutics and Professor and Chair of the Department of Molecular Pharmacology.
 
The mission of the Translational Research Laboratory (TRL) Core is to facilitate, implement, and support the needs of basic science researchers, clinical researchers, population researchers and clinical science collaborations. Interactions between basic scientists and clinicians are fostered to ensure the inclusion of scientifically sound correlative studies in clinical trials, and also to enable and assist research studies using clinical samples from patients enrolled in clinical trials. Emphasis is placed on the pursuit of institutional collaborations, allowing TRL to integrate with other Core laboratories to work closely together.
 
The following will be offered:
 
  • Pre-clinical studies on experimental drug therapies
     
  • Cell proliferation assay and drug cytotoxicity analysis
  • DNA and RNA isolation and quantification
  • Design and optimization of real-time PCR analysis
  • Protein isolation, western blot, and multiplex ELISA assay
 
  • Bio-specimen repository of clinical and population research protocol samples
 
  • Receiving, processing and storing human samples
  • Database management system to centralize information
 
  • General molecular genetic tests and special assays
  • KRAS mutations in colon cancer
  • EGFR mutations and ALK translations in lung cancer
  • P53 mutations in breast cancer
  • NRAS mutations in pancreatic cancer
  • VLH mutations in kidney cancer
 
  • PTEN mutations in brain cancer Circulating Tumor Cell (CTC) enumeration, enrichment and characterization
 

Pricing

Prices and availability vary - please contact us at 626-256-HOPE (4673) for more information. If you are a City of Hope employee, please click here for pricing.

 

 

Translational Research Team

Translational Research Laboratory Core

Translational Research Laboratory Core

The Translational Research Laboratory Core at City of Hope is under the direct supervision of  Yen Yun, M.D., Ph.D., Dr. & Mrs. Allen Y. Chao Chair in Developmental Cancer Therapeutics and Professor and Chair of the Department of Molecular Pharmacology.
 
The mission of the Translational Research Laboratory (TRL) Core is to facilitate, implement, and support the needs of basic science researchers, clinical researchers, population researchers and clinical science collaborations. Interactions between basic scientists and clinicians are fostered to ensure the inclusion of scientifically sound correlative studies in clinical trials, and also to enable and assist research studies using clinical samples from patients enrolled in clinical trials. Emphasis is placed on the pursuit of institutional collaborations, allowing TRL to integrate with other Core laboratories to work closely together.
 
The following will be offered:
 
  • Pre-clinical studies on experimental drug therapies
     
  • Cell proliferation assay and drug cytotoxicity analysis
  • DNA and RNA isolation and quantification
  • Design and optimization of real-time PCR analysis
  • Protein isolation, western blot, and multiplex ELISA assay
 
  • Bio-specimen repository of clinical and population research protocol samples
 
  • Receiving, processing and storing human samples
  • Database management system to centralize information
 
  • General molecular genetic tests and special assays
  • KRAS mutations in colon cancer
  • EGFR mutations and ALK translations in lung cancer
  • P53 mutations in breast cancer
  • NRAS mutations in pancreatic cancer
  • VLH mutations in kidney cancer
 
  • PTEN mutations in brain cancer Circulating Tumor Cell (CTC) enumeration, enrichment and characterization
 

Pricing

Pricing

Prices and availability vary - please contact us at 626-256-HOPE (4673) for more information. If you are a City of Hope employee, please click here for pricing.

 

 

Translational Research Team

Translational Research Team

Research Shared Services

City of Hope embodies the spirit of scientific collaboration by sharing services and core facilities with colleagues here and around the world.
 

Recognized nationwide for its innovative biomedical research, City of Hope's Beckman Research Institute is home to some of the most tenacious and creative minds in science.
City of Hope is one of only 41 Comprehensive Cancer Centers in the country, the highest designation awarded by the National Cancer Institute to institutions that lead the way in cancer research, treatment, prevention and professional education.
Learn more about City of Hope's institutional distinctions, breakthrough innovations and collaborations.
Support Our Research
By giving to City of Hope, you support breakthrough discoveries in laboratory research that translate into lifesaving treatments for patients with cancer and other serious diseases.
 
 
 
 
Media Inquiries/Social Media

For media inquiries contact:

Dominique Grignetti
800-888-5323
dgrignetti@coh.org

 

For sponsorships inquiries please contact:

Stefanie Sprester
213-241-7160
ssprester@coh.org

Christine Nassr
213-241-7112
cnassr@coh.org

 
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