Our Treatment Approach to Stomach Cancer
Stomach cancer is often at an advanced stage upon diagnosis, so treatment needs to be rapid and aggressive, requiring the expertise of specialists who are experienced in treating the disease.

City of Hope has one of the most experienced stomach cancer programs in the United States, with a multidisciplinary team of medical experts across different fields - including surgery, radiation oncology, medical oncology and supportive care medicine. Together, they work collaboratively to plan and implement a treatment regimen that is individually tailored to the patient to boost outcomes and quality of life.


Surgical removal of the tumor and surrounding suspicious tissue is often the primary treatment for stomach cancer. It can be curative for early stage stomach cancer patients and can also improve survival outcomes and reduce discomfort for advanced stomach cancer patients.
City of Hope’s surgeons specialize in minimally invasive and robotically-assisted surgical procedures for stomach cancer, which can remove cancerous tissue with less discomfort for the patient. By using smaller incisions compared to an open procedure, patients experience less pain, recover faster, have shorter hospital stays and are less likely to have post-surgical complications.

Radiation Therapy

Radiation is often used in conjunction with other therapies to treat stomach cancer. It is applied externally using one or more beams focused on the tumor or internally using radioactive seeds that are implanted into or near the tumor site (brachytherapy).
Radiation therapy can also improve quality of life by relieving pain, stopping bleeds and reducing stomach obstruction.
In addition to standard radiation regimens, City of Hope also offers Helical TomoTherapy , an advance technology combining radiation delivery with advanced imaging that results in more focused beams of radiation focused on the tumor while minimizing exposure to adjacent tissues and organs, including the heart, lungs and spine.


City of Hope uses a wide range of chemotherapy and targeted therapy drugs to treat localized and metastatic stomach cancer. In addition to standard drug regimens, patients have access to newly developed drugs (or drug combinations) through our clinical trials program.
Cancer fighting drugs can also enhance the effectiveness of surgery or radiation therapy, by shrinking the tumor before the procedure and making it easier to remove (neoadjuvant therapy), or given after the procedure to minimize the chance of recurrence (adjuvant therapy.)
Chemotherapy may also be given alongside radiation therapy to enhance the cancer-fighting effectiveness of both (chemoradiation.)
As part of the treatment team, a medical oncologist will evaluate the patient’s cancer, health and other factors, so that the chemotherapy, if appropriate, can be tailored to the patient throughout the continuum of care.

Become a Patient

If you have been diagnosed with stomach cancer or are looking for a second opinion consultation about your treatment, find out more about becoming a patient or contact us at 800-826-HOPE.