There is extensive collaboration between City of Hope clinicians and researchers to develop and evaluate new small intestine cancer therapies designed to improve survival and quality of life outcomes. City of Hope patients have access to a wide variety of clinical trials
ranging from new chemotherapy and targeted therapies, novel surgical techniques and new radiation approaches — all focused on enhancing treatment, detection and prevention of small intestine cancer.
Overexpression of the CEA protein in some intestinal cancers can be exploited for imaging purposes, since they will take in more of the drug M5A (which targets CEA-positive cancers) than normal tissues. Using this knowledge, researchers are investigating whether linking M5A to imaging agent 64Cu results in better visualization of tumors in a positron emission tomography (PET) scan.
Getting diagnosed with, and treatment for, small intestine cancer can have a profound impact on the patient’s caregivers as well. City of Hope researchers are currently studying this impact and whether a caregiver intervention program, consisting of home education and telephone support sessions, can help alleviate stress and boost quality of life.