A National Cancer Institute-designated Comprehensive Cancer Center

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Beckman Research Institute Departments and Divisions

The Department of Cancer Biology offers a multidisciplinary research and training environment in molecular biology, genetics, epigenetics and developmental biology.
 
Dedicated to discovering immune-based cancer therapies, the Department of Cancer Immunotherapeutics & Tumor Immunology conducts research in a new and evolving field and is known particularly for its studies using genetically engineered T-cells.
 
This department focuses on understanding the genetic and molecular bases of diabetes, developing novel treatment approaches for diabetes and preventing associated diseases such as cancer, heart disease and stroke.
 
 
Immunology
With a dual focus on immunology and structural biology, the Department of Immunology explores cancer immunology and biochemistry, antigen processing and T cell development.
Maintaining a strong emphasis on the interface of chemistry and biology, the Department of Molecular and Cellular Biology focuses on gene structure, modeling of antibodies, theoretical biology and more.
Established in 1996, the Department of Molecular Medicine seeks to understand basic mechanisms underlying cancer and other diseases for the purpose of developing novel molecular therapeutics.
The Department of Molecular Pharmacology aims to bridge the gap between the development of promising new drugs and their application in the clinic.
 
The Department of Neurosciences focuses on a range of research related to the brain and nervous system, including studies of molecular neurobiology/neurochemistry, neurophysiology, neuromorphology and molecular genetics.
 
Department researchers collaborate to better understand the causes of cancer, improve outcomes and develop ways to prevent cancer through discoveries made in population studies, survivorship, patterns of care and more.
 
  • Division of Cancer Etiology
    The goal of the Division of Cancer Etiology is to understand the causes of cancer. By understanding the causes of cancer, solutions can be developed to help prevent cancer, especially in people who are at highest risk.
     
  • Division of Clinical Cancer Genetics
    The Division of Clinical Cancer Genetics includes clinical services, research, and educational programs focusing on people who are at increased risk for developing cancer because of family history or personal risk factors.
     
  • Division of Outcomes Research
    The goal of the Division of Outcomes Research is to better understand the after-effects (physical, emotional, and social) of cancer and its treatment.
    • Center for Cancer Survivorship
      This is a clinical long-term follow-up program designed to create a bridge between cancer treatment and community medical care.
       
  • Division of Nursing Research and Education
    The Division of Nursing Research and Education is well recognized on a national level for its research and education focused on nursing care for patients with cancer, which has helped to increase the quality of care provided to cancer patients across the United States.
The Department of Radiation Biology studies the fundamental mechanisms of cancers and radiation resistance in cancer cells to find a solution to improve the efficacy of radiation therapy.

Research in the Department of Virology supports eight faculty members and laboratories with research including viral vector development, viral immunology, and vaccine development. The program includes early phase clinical trials in gene transfer and in vaccine evaluation.

  • Translational Vaccine Research
    The Division of Translational Vaccine Research (TVR) develops vaccines to combat hematologic malignancies, solid tumors, and infectious pathogens such as CMV and HIV.
     
 

Departments and Divisions

Beckman Research Institute Departments and Divisions

The Department of Cancer Biology offers a multidisciplinary research and training environment in molecular biology, genetics, epigenetics and developmental biology.
 
Dedicated to discovering immune-based cancer therapies, the Department of Cancer Immunotherapeutics & Tumor Immunology conducts research in a new and evolving field and is known particularly for its studies using genetically engineered T-cells.
 
This department focuses on understanding the genetic and molecular bases of diabetes, developing novel treatment approaches for diabetes and preventing associated diseases such as cancer, heart disease and stroke.
 
 
Immunology
With a dual focus on immunology and structural biology, the Department of Immunology explores cancer immunology and biochemistry, antigen processing and T cell development.
Maintaining a strong emphasis on the interface of chemistry and biology, the Department of Molecular and Cellular Biology focuses on gene structure, modeling of antibodies, theoretical biology and more.
Established in 1996, the Department of Molecular Medicine seeks to understand basic mechanisms underlying cancer and other diseases for the purpose of developing novel molecular therapeutics.
The Department of Molecular Pharmacology aims to bridge the gap between the development of promising new drugs and their application in the clinic.
 
The Department of Neurosciences focuses on a range of research related to the brain and nervous system, including studies of molecular neurobiology/neurochemistry, neurophysiology, neuromorphology and molecular genetics.
 
Department researchers collaborate to better understand the causes of cancer, improve outcomes and develop ways to prevent cancer through discoveries made in population studies, survivorship, patterns of care and more.
 
  • Division of Cancer Etiology
    The goal of the Division of Cancer Etiology is to understand the causes of cancer. By understanding the causes of cancer, solutions can be developed to help prevent cancer, especially in people who are at highest risk.
     
  • Division of Clinical Cancer Genetics
    The Division of Clinical Cancer Genetics includes clinical services, research, and educational programs focusing on people who are at increased risk for developing cancer because of family history or personal risk factors.
     
  • Division of Outcomes Research
    The goal of the Division of Outcomes Research is to better understand the after-effects (physical, emotional, and social) of cancer and its treatment.
    • Center for Cancer Survivorship
      This is a clinical long-term follow-up program designed to create a bridge between cancer treatment and community medical care.
       
  • Division of Nursing Research and Education
    The Division of Nursing Research and Education is well recognized on a national level for its research and education focused on nursing care for patients with cancer, which has helped to increase the quality of care provided to cancer patients across the United States.
The Department of Radiation Biology studies the fundamental mechanisms of cancers and radiation resistance in cancer cells to find a solution to improve the efficacy of radiation therapy.

Research in the Department of Virology supports eight faculty members and laboratories with research including viral vector development, viral immunology, and vaccine development. The program includes early phase clinical trials in gene transfer and in vaccine evaluation.

  • Translational Vaccine Research
    The Division of Translational Vaccine Research (TVR) develops vaccines to combat hematologic malignancies, solid tumors, and infectious pathogens such as CMV and HIV.
     
 
Research Overview
Research pioneered at City of Hope has improved the lives of men, women and children throughout the world.
 
Beckman Research Institute

Beckman Research Institute of City of Hope is internationally  recognized for its innovative translational biomedical research.
 

Comprehensive Cancer Center
City of Hope is one of only 41 Comprehensive Cancer Centers in the country, the highest designation awarded by the National Cancer Institute to institutions that lead the way in cancer research, treatment, prevention and education.

Our Scientists

Our research laboratories are led by the best and brightest minds in scientific research.
 

Technology & Licensing
The Center for Applied Technology Development offers broad expertise in
technology transfer and licensing, biologics manufacturing, quality assurance and regulatory affairs.

Research Shared Services

City of Hope embodies the spirit of scientific collaboration by sharing services and core facilities with colleagues here and around the world.
 

NEWS & UPDATES
  • Rob Darakjian was diagnosed with acute lymphoblastic leukemia at just 19 years old. He began chemotherapy and was in and out of the hospital for four months. After his fourth round of treatment, he received a bone marrow transplantation from an anonymous donor. Today, he’s cancer free. In his first post, ...
  • Advanced age tops the list among breast cancer risk factor for women. Not far behind is family history and genetics. Two City of Hope researchers delving deep into these issues recently received important grants to advance their studies. Arti Hurria, M.D., director of the Cancer and Aging Research Program, and ...
  • City of Hope is extending the reach of its lifesaving mission well beyond U.S. borders. To that end, three distinguished City of Hope leaders visited China earlier this year to lay the foundation for the institution’s new International Medicine Program. The program is part of City of Hope’s strategi...
  • A hallmark of cancer is that it doesn’t always limit itself to a primary location. It spreads. Breast cancer and lung cancer in particular are prone to spread, or metastasize, to the brain. Often the brain metastasis isn’t discovered until years after the initial diagnosis, just when patients were beginning to ...
  • Blueberries, cinnamon, baikal scullcap, grape seed extract (and grape skin extract), mushrooms, barberry, pomegranates … all contain compounds with the potential to treat, or prevent, cancer. Scientists at City of Hope have found tantalizing evidence of this potential and are determined to explore it to t...
  • Most women who are treated for breast cancer with a mastectomy do not choose to undergo reconstructive surgery. The reasons for this, according to a recent JAMA Surgery study, vary. Nearly half say they do not want any additional surgery, while nearly 34 percent say breast cancer reconstruction simply isn’t imp...
  • The leading risk factor for breast cancer is simply being a woman. The second top risk factor is getting older. Obviously, these two factors cannot be controlled, which is why all women should be aware of their risk and how to minimize those risks. Many risk factors can be mitigated, and simple changes can lead...
  • All women are at some risk of developing the disease in their lifetimes, but breast cancer, like other cancers, has a disproportionate effect on minorities. Although white women have the highest incidence of breast cancer, African-American women have the highest breast cancer death rates of all racial and ethni...
  • First, the good news: HIV infections have dropped dramatically over the past 30 years. Doctors, researchers and health officials have made great strides in preventing and treating the disease, turning what was once a death sentence into, for some, a chronic condition. Now, the reality check: HIV is still a worl...
  • Screening for breast cancer has dramatically increased the number of cancers found before they cause symptoms – catching the disease when it is most treatable and curable. Mammograms, however, are not infallible. It’s important to conduct self-exams, and know the signs and symptoms that should be checked by a h...
  • Rob Darakjian was diagnosed with acute lymphoblastic leukemia at just 19 years old. He began chemotherapy and was in and out of the hospital for four months. After his fourth round of treatment, he received a bone marrow transplantation from an anonymous donor. Today, he’s cancer free.   In his previ...
  • In a single day, former professional triathlete Lisa Birk learned she couldn’t have children and that she had breast cancer. “Where do you go from there?” she asks. For Birk, who swims three miles, runs 10 miles and cycles every day, the answer  ultimately was a decision to take control of her cancer care. Afte...
  • More and more people are surviving cancer, thanks to advanced cancer treatments and screening tools. Today there are nearly 14.5 million cancer survivors in the United States. But in up to 20 percent of cancer patients, the disease ultimately spreads to their brain. Each year, nearly 170,000 new cases of brain ...
  • Cancer cells are masters of survival. Despite excessive damage to their most basic workings and the constant vigilance of the body’s immune system, they manage to persevere. Much of this extraordinary ability to survive falls under the control of proteins bearing the name STAT, short for signal transducer and a...
  • One person receives the breast cancer diagnosis, but the cancer affects the entire family. Couples, in particular, can find the diagnosis and treatment challenging, especially if they have traditional male/female communication styles. “Though every individual is unique, men and women often respond differently d...