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Beckman Research Institute Departments and Divisions

The Department of Cancer Biology offers a multidisciplinary research and training environment in molecular biology, genetics, epigenetics and developmental biology.
 
Dedicated to discovering immune-based cancer therapies, the Department of Cancer Immunotherapeutics & Tumor Immunology conducts research in a new and evolving field and is known particularly for its studies using genetically engineered T-cells.
 
This department focuses on understanding the genetic and molecular bases of diabetes, developing novel treatment approaches for diabetes and preventing associated diseases such as cancer, heart disease and stroke.
 
 
The Department of Experimental Therapeutics develops vaccines to combat hematologic malignancies, solid tumors, and infectious pathogens such as CMV and HIV.
 
Immunology
With a dual focus on immunology and structural biology, the Department of Immunology explores cancer immunology and biochemistry, antigen processing and T cell development.
Maintaining a strong emphasis on the interface of chemistry and biology, the Department of Molecular and Cellular Biology focuses on gene structure, modeling of antibodies, theoretical biology and more.
Established in 1996, the Department of Molecular Medicine seeks to understand basic mechanisms underlying cancer and other diseases for the purpose of developing novel molecular therapeutics.
The Department of Molecular Pharmacology aims to bridge the gap between the development of promising new drugs and their application in the clinic.
 
The Department of Neurosciences focuses on a range of research related to the brain and nervous system, including studies of molecular neurobiology/neurochemistry, neurophysiology, neuromorphology and molecular genetics.
 
Department researchers collaborate to better understand the causes of cancer, improve outcomes and develop ways to prevent cancer through discoveries made in population studies, survivorship, patterns of care and more.
 
  • Division of Cancer Etiology
    The goal of the Division of Cancer Etiology is to understand the causes of cancer. By understanding the causes of cancer, solutions can be developed to help prevent cancer, especially in people who are at highest risk.
     
  • Division of Clinical Cancer Genetics
    The Division of Clinical Cancer Genetics includes clinical services, research, and educational programs focusing on people who are at increased risk for developing cancer because of family history or personal risk factors.
     
  • Division of Outcomes Research
    The goal of the Division of Outcomes Research is to better understand the after-effects (physical, emotional, and social) of cancer and its treatment.
    • Center for Cancer Survivorship
      This is a clinical long-term follow-up program designed to create a bridge between cancer treatment and community medical care.
       
  • Division of Nursing Research and Education
    The Division of Nursing Research and Education is well recognized on a national level for its research and education focused on nursing care for patients with cancer, which has helped to increase the quality of care provided to cancer patients across the United States.
The Department of Radiation Biology studies the fundamental mechanisms of cancers and radiation resistance in cancer cells to find a solution to improve the efficacy of radiation therapy.

Research in the Department of Virology supports eight faculty members and laboratories with research including viral vector development, viral immunology, and vaccine development. The program includes early phase clinical trials in gene transfer and in vaccine evaluation.
 

Departments and Divisions

Beckman Research Institute Departments and Divisions

The Department of Cancer Biology offers a multidisciplinary research and training environment in molecular biology, genetics, epigenetics and developmental biology.
 
Dedicated to discovering immune-based cancer therapies, the Department of Cancer Immunotherapeutics & Tumor Immunology conducts research in a new and evolving field and is known particularly for its studies using genetically engineered T-cells.
 
This department focuses on understanding the genetic and molecular bases of diabetes, developing novel treatment approaches for diabetes and preventing associated diseases such as cancer, heart disease and stroke.
 
 
The Department of Experimental Therapeutics develops vaccines to combat hematologic malignancies, solid tumors, and infectious pathogens such as CMV and HIV.
 
Immunology
With a dual focus on immunology and structural biology, the Department of Immunology explores cancer immunology and biochemistry, antigen processing and T cell development.
Maintaining a strong emphasis on the interface of chemistry and biology, the Department of Molecular and Cellular Biology focuses on gene structure, modeling of antibodies, theoretical biology and more.
Established in 1996, the Department of Molecular Medicine seeks to understand basic mechanisms underlying cancer and other diseases for the purpose of developing novel molecular therapeutics.
The Department of Molecular Pharmacology aims to bridge the gap between the development of promising new drugs and their application in the clinic.
 
The Department of Neurosciences focuses on a range of research related to the brain and nervous system, including studies of molecular neurobiology/neurochemistry, neurophysiology, neuromorphology and molecular genetics.
 
Department researchers collaborate to better understand the causes of cancer, improve outcomes and develop ways to prevent cancer through discoveries made in population studies, survivorship, patterns of care and more.
 
  • Division of Cancer Etiology
    The goal of the Division of Cancer Etiology is to understand the causes of cancer. By understanding the causes of cancer, solutions can be developed to help prevent cancer, especially in people who are at highest risk.
     
  • Division of Clinical Cancer Genetics
    The Division of Clinical Cancer Genetics includes clinical services, research, and educational programs focusing on people who are at increased risk for developing cancer because of family history or personal risk factors.
     
  • Division of Outcomes Research
    The goal of the Division of Outcomes Research is to better understand the after-effects (physical, emotional, and social) of cancer and its treatment.
    • Center for Cancer Survivorship
      This is a clinical long-term follow-up program designed to create a bridge between cancer treatment and community medical care.
       
  • Division of Nursing Research and Education
    The Division of Nursing Research and Education is well recognized on a national level for its research and education focused on nursing care for patients with cancer, which has helped to increase the quality of care provided to cancer patients across the United States.
The Department of Radiation Biology studies the fundamental mechanisms of cancers and radiation resistance in cancer cells to find a solution to improve the efficacy of radiation therapy.

Research in the Department of Virology supports eight faculty members and laboratories with research including viral vector development, viral immunology, and vaccine development. The program includes early phase clinical trials in gene transfer and in vaccine evaluation.
 
Research Overview
Research pioneered at City of Hope has improved the lives of men, women and children throughout the world.
 
Beckman Research Institute

Beckman Research Institute of City of Hope is internationally  recognized for its innovative translational biomedical research.
 

Comprehensive Cancer Center
City of Hope is one of only 41 Comprehensive Cancer Centers in the country, the highest designation awarded by the National Cancer Institute to institutions that lead the way in cancer research, treatment, prevention and education.

Our Scientists

Our research laboratories are led by the best and brightest minds in scientific research.
 

Technology & Licensing
The Center for Applied Technology Development offers broad expertise in
technology transfer and licensing, biologics manufacturing, quality assurance and regulatory affairs.

Research Shared Services

City of Hope embodies the spirit of scientific collaboration by sharing services and core facilities with colleagues here and around the world.
 



NEWS & UPDATES
  • To celebrate the beginning of Lunar New  Year 2015, City of Hope honored not just a new lunar calendar, but also the diversity of the community it serves. On Jan. 21, as tens of thousands of people celebrated Lunar New Year (and the arrival of the Year of the Ram) in the streets of L.A.’s Chinatown, City of [&#...
  • The breakthroughs that have revolutionized cancer treatment, transforming cancer in many cases to a very manageable and even curable disease, started out as just ideas. “I will often tell patients there’s no therapy we’re using to help them that wasn’t derived from somebody’s idea in some laboratory, working la...
  • The prostate cancer screening debate, at least as it relates to regular assessment of prostate specific antigen levels, is far from over. The U.S. Preventive Services Task Force recommended against routine PSA screening for prostate cancer in 2012, maintaining that the routine use of the PSA blood test does mor...
  • Cancer patients should get more than medical treatment. They should get comprehensive, evidence-based care that addresses their full range of needs. That kind of patient-focused care is City of Hope’s specialty. Under the guidance of Dawn Gross, M.D., Ph.D., the new Arthur M. Coppola Family Chair in Suppo...
  • Think twice before tossing out those hormone replacement pills. Although a new Lancet study suggests that hormone replacement therapy could increase a woman’s risk of ovarian cancer, a City of Hope expert urges women to keep this news in perspective. Hormone replacement therapy is prescribed to help allev...
  • Don’t know what to take, or send, that friend of yours in the hospital? Try a paper plate — filled not with cookies or sweets, but an image of yourself. Ilana Massi, currently undergoing treatment at City of Hope for acute myeloid leukemia, can vouch for the power of such a gift. She’s surrounded herself [̷...
  • With precision medicine now a national priority, City of Hope has joined a novel research partnership designed to further understanding of cancer at the molecular level, ultimately leading to more targeted cancer treatments. The Oncology Research Information Exchange Network, or ORIEN, is the world’s larg...
  • The spinal cord is an integral part of the human body, connecting the brain to everything else. So when a tumor grows on the spine, any messages that the brain tries to send to the rest of the body are interrupted, making everyday tasks — such as walking — more difficult. This year an estimated 22,850 […]
  • Each year, thousands of patients with hematologic malignancies undergo allogeneic stem cell transplantation (that is, they receive a donor’s stem cells), offering them a chance at cure. Graft-versus-host disease is a potentially deadly complication of this therapy and occurs in approximately 25 to 60 perc...
  • Bertram Yuh, M.D., assistant clinical professor in the Division of Urology and Urologic Oncology at City of Hope, offers his perspective on the benefits of surgery for aggressive prostate cancer. For men walking out of the doctor’s office after a diagnosis of cancer, the reality can hit like a ton of bricks. Th...
  • Although many Hispanic women face a high risk of mutations in the BRCA1 and BRCA2 genes – increasing their risk of breast and ovarian cancer – screenings for these mutations can be prohibitively expensive in Mexico and other Latin American countries. As a result, too many women don’t get the information t...
  • Providing lung cancer treatments to patients when their cancer is at its earliest and most treatable stages will now be a more attainable goal: Medicare has agreed to cover lung cancer screening for those beneficiaries who meet the requirements. The only proven way to detect lung cancer early enough to save liv...
  • At City of Hope, innovative scientific research, important clinical studies and vital construction projects are all powered by philanthropy. Generous supporters fuel a powerful and diverse range of progress in science and medicine, enabling researchers and clinicians to improve cancer treatments and create cure...
  • Trevor Hoffman was only 21 when he was diagnosed with a rare form of cancer, but not even cancer could keep him off his motorcycles. (He has one for racing, and a couple just for fun.) Now a cancer survivor, Hoffman, who lives in La Verne, California, wrapped up his treatment Jan. 19 – just one day […]
  • Valentine’s Day is synonymous with dinner reservations, red roses, heart-shaped boxes of chocolates and — more often than not — unrealistically high expectations. Managing those expectations is great advice for all couples on Feb. 14 — and is especially important for couples confronting a cancer diagnosis. Focu...