A National Cancer Institute-designated Comprehensive Cancer Center

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Why Choose City of Hope?

Institutional distinctions
 
  • City of Hope is one of 41 comprehensive cancer centers, the highest designation bestowed by the National Cancer Institute for excellence in cancer treatment, research, prevention and education.
  • City of Hope is ranked as one of “America’s Best Hospitals” in cancer by U.S.News & World Report.
  • City of Hope is a founding member of the National Comprehensive Cancer Network (NCCN), meaning our research and treatment protocols advance care throughout the nation.
  • In the 2014 fiscal year, City of Hope was awarded more than $72.9 million in research grants and received approximately $249.8 million in revenues from patented technologies.
  • City of Hope has earned its sixth consecutive Press Ganey Guardian of Excellence Award.
  • City of Hope is part of ORIEN (Oncology Research Information Exchange Network), the world's largest cancer research collaboration devoted to precision medicine.
  • We were recently awarded the highest level of accreditation by the American College of Surgeons Commision on Cancer for our exceptional level of cancer care, "Three-Year with Commendation." This is the second consecutive time that we have received this prestigious rating.
  • City of Hope has earned the highest rating - 4 stars - from the nation’s leading charity watchdog, Charity Navigator. The four-star rating reflect City of Hope's sound fiscal management, financial stability and growth.
 
A record of innovation
 
  • Numerous breakthrough cancer drugs, including Herceptin, Rituxan and Avastin, are based on technology pioneered by City of Hope and are saving lives worldwide.
  • Millions of people with diabetes benefit from synthetic human insulin, developed through research conducted at City of Hope.
  • City of Hope was a pioneer in bone marrow and stem cell transplants - and our program is now one of the largest, most successful programs of its kind in the world. We’ve performed more than 12,000 bone marrow and stem cell transplants, with survival rates that are unparalleled.
  • Surgeons at City of Hope have performed more than 10,000 robotic procedures for prostate, kidney, colon, liver, bladder, gynecologic, oral and other cancers.
 
Speed, efficiency and collaboration
 
  • Our research facilities set us apart. We have not one, but three, manufacturing facilities on campus that manufacture both biologic and chemical compounds to good manufacturing practice (GMP) standards. This infrastructure helps us quickly turn breakthrough discoveries into lifesaving therapies.
  • City of Hope has more than 300 patents and currently have 30 investigational new drug applications. These numbers are exceptionally large for an organization of City of Hope’s size, reflecting our commitment to innovation and speeding treatments to patients.
  • A uniquely collaborative environment makes it easy for laboratory and clinical researchers at City of Hope to more quickly translate breakthroughs into therapies.
  • Beckman Research Institute of City of Hope was the first of five Beckman Institutes in the United States, which together have fueled scientific advances for more than a generation.
 
Science that is saving lives
 
  • City of Hope researchers are investigating ways to harness the body’s natural defenses to fight cancer, an approach known as “immunotherapy.”
    • One approach strikes a dual blow - shutting off a gene that promotes cancer while stimulating the immune system to act - in an effort to fight lymphoma and melanoma as well as brain, ovarian and prostate cancers.
    • Other studies are focused on engaging every stage of the immune response to defeat breast cancer.
  • City of Hope scientists studying “superfoods” have found that an extract of white button mushrooms can help block hormones that cause breast cancer and prostate cancer to grow and spread.  They’re also researching the anti-cancer properties of other “superfoods” such as blueberries, pomegranates and grape seed extract.
  • Because life after cancer treatment can present both physical and emotional challenges, City of Hope creates a bridge between treatment and ongoing support. The Center for Cancer Survivorship provides specialized follow-up care and education for survivors of pediatric, prostate and breast cancers. The resulting research is helping physicians understand the long-term effects of cancer and
    its treatment - influencing how care is delivered today at City of Hope and beyond.

Beyond the study of cancer
 
  • By investigating the molecular mechanisms of diabetes complications, City of Hope scientists are helping develop new treatments for them. They also are studying the use of blood stem cell transplantation to reboot the immune system in type 1 diabetes, an autoimmune disease.
  • City of Hope is a national leader in islet cell transplantation, which has the potential to reverse type 1 diabetes. In addition, we provide islet cells for research at other institutions throughout the U.S.
  • Researchers here are investigating new connections between diabetes and cancer, such as inflammation. What we discover about one disease could hold cures to advances against the other.
     
Toward a lasting cure for HIV/AIDS
 
  • City of Hope scientists pioneered the application of blood stem cell transplants to treat patients with HIV and AIDS-related lymphoma. Our researchers used a new form of gene therapy to achieve the first long-term persistence of anti-HIV genes in patients with AIDS-related lymphoma. This treatment ultimately may cure not only lymphoma, but also HIV/AIDS, and our researchers are now expanding their studies with a new clinical trial.
 
The philanthropic support that makes it all possible
 
  • City of Hope is powered by philanthropy. It was launched in the firm belief that all of us have the potential to change the fate of individuals even as we improve medical care overall.
  • “There is no profit in curing the body if, in the process, we destroy the soul.” Those words were spoken by Samuel H. Golter, one of our early leaders, and they remain the credo that guides City of Hope’s approach to patient care. We are committed to treating the whole person not only by providing the best medical care possible, but also by providing that care in an atmosphere of kindness and compassion.
  • Year after year, foundations, philanthropists, business leaders, global corporations, small businesses and hundreds of thousands of other caring individuals of all ages contribute generously to support the lifesaving work of City of Hope.
  • Many professional sports organizations have supported City of Hope, including the Los Angeles Dodgers, the Los Angeles Kings, Major League Soccer’s Chivas USA and the National Football League. City of Hope has been named the official charity of the historic Northern Trust Open, and through 2025, will partner with the Northern Trust and PGA TOUR to raise funds and awareness for cancer and diabetes research.

Why Choose City of Hope?

Why Choose City of Hope?

Institutional distinctions
 
  • City of Hope is one of 41 comprehensive cancer centers, the highest designation bestowed by the National Cancer Institute for excellence in cancer treatment, research, prevention and education.
  • City of Hope is ranked as one of “America’s Best Hospitals” in cancer by U.S.News & World Report.
  • City of Hope is a founding member of the National Comprehensive Cancer Network (NCCN), meaning our research and treatment protocols advance care throughout the nation.
  • In the 2014 fiscal year, City of Hope was awarded more than $72.9 million in research grants and received approximately $249.8 million in revenues from patented technologies.
  • City of Hope has earned its sixth consecutive Press Ganey Guardian of Excellence Award.
  • City of Hope is part of ORIEN (Oncology Research Information Exchange Network), the world's largest cancer research collaboration devoted to precision medicine.
  • We were recently awarded the highest level of accreditation by the American College of Surgeons Commision on Cancer for our exceptional level of cancer care, "Three-Year with Commendation." This is the second consecutive time that we have received this prestigious rating.
  • City of Hope has earned the highest rating - 4 stars - from the nation’s leading charity watchdog, Charity Navigator. The four-star rating reflect City of Hope's sound fiscal management, financial stability and growth.
 
A record of innovation
 
  • Numerous breakthrough cancer drugs, including Herceptin, Rituxan and Avastin, are based on technology pioneered by City of Hope and are saving lives worldwide.
  • Millions of people with diabetes benefit from synthetic human insulin, developed through research conducted at City of Hope.
  • City of Hope was a pioneer in bone marrow and stem cell transplants - and our program is now one of the largest, most successful programs of its kind in the world. We’ve performed more than 12,000 bone marrow and stem cell transplants, with survival rates that are unparalleled.
  • Surgeons at City of Hope have performed more than 10,000 robotic procedures for prostate, kidney, colon, liver, bladder, gynecologic, oral and other cancers.
 
Speed, efficiency and collaboration
 
  • Our research facilities set us apart. We have not one, but three, manufacturing facilities on campus that manufacture both biologic and chemical compounds to good manufacturing practice (GMP) standards. This infrastructure helps us quickly turn breakthrough discoveries into lifesaving therapies.
  • City of Hope has more than 300 patents and currently have 30 investigational new drug applications. These numbers are exceptionally large for an organization of City of Hope’s size, reflecting our commitment to innovation and speeding treatments to patients.
  • A uniquely collaborative environment makes it easy for laboratory and clinical researchers at City of Hope to more quickly translate breakthroughs into therapies.
  • Beckman Research Institute of City of Hope was the first of five Beckman Institutes in the United States, which together have fueled scientific advances for more than a generation.
 
Science that is saving lives
 
  • City of Hope researchers are investigating ways to harness the body’s natural defenses to fight cancer, an approach known as “immunotherapy.”
    • One approach strikes a dual blow - shutting off a gene that promotes cancer while stimulating the immune system to act - in an effort to fight lymphoma and melanoma as well as brain, ovarian and prostate cancers.
    • Other studies are focused on engaging every stage of the immune response to defeat breast cancer.
  • City of Hope scientists studying “superfoods” have found that an extract of white button mushrooms can help block hormones that cause breast cancer and prostate cancer to grow and spread.  They’re also researching the anti-cancer properties of other “superfoods” such as blueberries, pomegranates and grape seed extract.
  • Because life after cancer treatment can present both physical and emotional challenges, City of Hope creates a bridge between treatment and ongoing support. The Center for Cancer Survivorship provides specialized follow-up care and education for survivors of pediatric, prostate and breast cancers. The resulting research is helping physicians understand the long-term effects of cancer and
    its treatment - influencing how care is delivered today at City of Hope and beyond.

Beyond the study of cancer
 
  • By investigating the molecular mechanisms of diabetes complications, City of Hope scientists are helping develop new treatments for them. They also are studying the use of blood stem cell transplantation to reboot the immune system in type 1 diabetes, an autoimmune disease.
  • City of Hope is a national leader in islet cell transplantation, which has the potential to reverse type 1 diabetes. In addition, we provide islet cells for research at other institutions throughout the U.S.
  • Researchers here are investigating new connections between diabetes and cancer, such as inflammation. What we discover about one disease could hold cures to advances against the other.
     
Toward a lasting cure for HIV/AIDS
 
  • City of Hope scientists pioneered the application of blood stem cell transplants to treat patients with HIV and AIDS-related lymphoma. Our researchers used a new form of gene therapy to achieve the first long-term persistence of anti-HIV genes in patients with AIDS-related lymphoma. This treatment ultimately may cure not only lymphoma, but also HIV/AIDS, and our researchers are now expanding their studies with a new clinical trial.
 
The philanthropic support that makes it all possible
 
  • City of Hope is powered by philanthropy. It was launched in the firm belief that all of us have the potential to change the fate of individuals even as we improve medical care overall.
  • “There is no profit in curing the body if, in the process, we destroy the soul.” Those words were spoken by Samuel H. Golter, one of our early leaders, and they remain the credo that guides City of Hope’s approach to patient care. We are committed to treating the whole person not only by providing the best medical care possible, but also by providing that care in an atmosphere of kindness and compassion.
  • Year after year, foundations, philanthropists, business leaders, global corporations, small businesses and hundreds of thousands of other caring individuals of all ages contribute generously to support the lifesaving work of City of Hope.
  • Many professional sports organizations have supported City of Hope, including the Los Angeles Dodgers, the Los Angeles Kings, Major League Soccer’s Chivas USA and the National Football League. City of Hope has been named the official charity of the historic Northern Trust Open, and through 2025, will partner with the Northern Trust and PGA TOUR to raise funds and awareness for cancer and diabetes research.
Welcome to City of Hope
City of Hope is a new model of cancer center, focused on rapidly transforming scientific discoveries into better treatments and better prevention strategies for cancer, diabetes, HIV/AIDS and other life-threatening diseases.

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Learn about the talented individuals who are leading City of Hope towards the next horizon of treatments and cures for life-threatening diseases.

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City of Hope's institutional distinctions, breakthrough innovations and collaborations.
 


NEWS & UPDATES
  • The outlook and length of survival has not changed much in the past 25 years for patients suffering from an aggressive form of pancreatic cancer known as pancreatic ductal adenocarcinoma (PDAC). These patients still have few options for therapy; currently available therapies are generally toxic and do not incre...
  • “With bladder cancer, the majority of patients that I see can be cured,” said urologist Kevin Chan, M.D., head of reconstructive urology at City of Hope. “The challenge is to get patients the same quality of life that they had before surgery.” To meet this challenge, Chan and the urologic team at City of Hope [...
  • Already pioneers in the use of immunotherapy, City of Hope researchers are now testing the bold approach to cancer treatment against one of medicine’s biggest challenges: brain cancer. This month, they will launch a clinical trial using patients’ own modified T cells to fight advanced brain tumors. One of but a...
  • Brain cancer may be one of the most-frightening diagnoses people can receive, striking at the very center of who we are as individuals. Further, it often develops over time, causing no symptoms until it’s already advanced. Listen to City of Hope Radio as Behnam Badie, M.D., director of the Brain Tumor Pro...
  • The whole is greater than the sum of its parts. It takes a village. No man is an island. Choose your aphorism: It’s a simple truth that collaboration usually is better than isolation. That’s especially true when you’re trying to introduce healthful habits and deliver health care to people at risk of disease and...
  • When Maryland Governor Larry Hogan announced earlier this week that he has the most common form of non-Hodgkin lymphoma, he was giving voice to the experience of more than 71,000 Americans each year. The announcement came with Hogan’s promise to stay in office while undergoing aggressive treatment for the...
  • The spine can be affected by many different kinds of tumors. Malignant, or cancerous, tumors can arise within the spine itself. Secondary spinal tumors, which are actually much more common, begin as cancers in another part of the body, such as the breast and prostate, and then spread, or metastasize, to the spi...
  • Although most cancer occurs in older adults, the bulk of cancer research doesn’t focus on this vulnerable and fast-growing population. City of Hope and its Cancer and Aging Research Team aim to change that, and they’re getting a significant boost from Professional Practice Leader Peggy Burhenn, R.N....
  • Liz Graef-Larcher’s first brain tumor was discovered by accident six years ago. The then-48-year-old with a long history of sinus problems and headaches had been sent for an MRI, and the scan found a lesion in her brain called a meningioma – a tumor that arises in the meninges, the layers of tissue that cover a...
  • The colon and rectum are parts of the body’s gastrointestinal system, also called the digestive tract. After food is digested in the stomach and nutrients are absorbed in the small intestine, the remaining material moves down into the lower large intestine (colon) where water and nutrients are absorbed. The low...
  • If there is one truism about hospital stays it is that patients want to get out. For many, however, the joy of being discharged is tempered by the unexpected challenges that recovery in a new setting may pose. Even with professional help, the quality of care and treatment that patients receive at City of Hope [...
  • Jana Portnow, M.D., associate director of the Brain Tumor Program at City of Hope, didn’t expect to specialize in treating brain tumors. But, early in her career, she undertook a year of research on pain management and palliative care and, in that program, got to know many patients with brain tumors. After that...
  • Ask any patient: Nurses are as pivotal in their care as doctors. They answer the call of a patient in the middle of the night, they hold the patient’s hand as he or she takes on yet another round of treatment and, in the best-case scenario, they wave goodbye as the patient leaves the hospital, […]
  • Many oncologists, not to mention their patients, might think that there’s no place for mathematical analysis in the treatment of cancer. They might think that all treatment decisions are based on unique factors affecting individual patients, with no connection to other patients and their treatment regimen...
  • Within three days in 2007, Stephanie Hosford, then 37, learned that she was pregnant with her long-awaited second child – and that she had triple-negative breast cancer. Soon afterward, Hosford discovered that she and her husband, Grant, had been approved to adopt a little girl from China.  After encountering m...