A National Cancer Institute-designated Comprehensive Cancer Center

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Leukemia and Lymphoma Programs

At City of Hope, our team of pediatric experts provides comprehensive care for children with leukemia and lymphoma. Leukemia is a cancer of the blood and the most common cancer in children, accounting for approximately 40 percent of all cancer diagnoses in children. Lymphomas are cancers that develop in the body’s lymphatic system and are the third most common pediatric cancer, after leukemia and brain tumors. Our program treats patients with a range of leukemias and lymphomas, including:

Leukemias
 
  • Acute lymphoblastic leukemia (ALL)
  • Acute myeloid leukemia (AML)
  • Chronic myelogenous leukemia (CML)
     
Lymphomas
 
  • Hodgkin lymphoma
  • Non-Hodgkin lymphoma
    • Anaplastic large-cell lymphoma (ALCL)
    • B-cell lymphoma (Burkitt and Burkitt-like lymphoma)
    • Diffuse large B-cell lymphoma (DLBC)
    • Lymphoblastic lymphoma
    • T-cell lymphoma
    • MK-cell lymphoma
       
We treat newly diagnosed patients, as well as patients referred to us from other centers who come to City of Hope to continue their treatment, manage complications of treatment or develop new treatment strategies for cancers not responding to treatment, or for situations in which they have experienced a relapse. For children who fail to respond to treatment or experience a relapse, City of Hope has a renowned program in stem cell transplantation, as well as ongoing studies into novel therapies for relapsed/refractory leukemia.
 
Each type of childhood cancer is treated differently, based on what has been found to be most effective in destroying the particular type of cancer cell. The most common type of cancer treatment for leukemia and lymphoma is chemotherapy. In some cases, radiation therapy and/or stem cell transplant may be recommended. Immunotherapy, or treatment that uses certain parts of the immune system to fight cancer, may be used as well.

A unique benefit of being treated at City of Hope is that we treat young children, adolescents and young adults, ensuring a continuum of care through the years for this special group of patients. Adolescents and young adults may be eligible for clinical studies and novel treatments available for adult patients at City of Hope, while still benefitting from the patient and family-centered approach of the pediatric program.

Our program offers both outstanding medical treatment and psychosocial support to young cancer patients and their family members. Pediatric oncologists, hematologists, surgeons, radiation oncologists, pathologists and other specialists work in concert to develop a targeted, effective treatment plan.  At the same time, professionals in psychology; social work; child life; recreational, occupational and physical therapy; music therapy; and school reintegration provide individual attention and group activities for patients and their families.

Meet the members of City of Hope’s pediatric leukemia and lymphoma team:
 
The majority of children diagnosed with leukemia or lymphoma are cured; however, there can be long-term side effects. Our Center for Cancer Survivorship clinic is specially designed to meet the follow-up needs of childhood cancer survivors, who are evaluated annually by a team of health care professionals with expertise in survivorship issues.
 
Your child may have the opportunity to participate in a research study or clinical trial through our participation in the Children’s Oncology Group (COG) and our designation as one of only 41 National Cancer Institute (NCI) Comprehensive Cancer Centers in the U.S. More information about our pediatric cancer research, including ongoing clinical trials, is available on City of Hope’s Clinical Trials Online website.
 

Leukemia and Lymphoma

Leukemia and Lymphoma Programs

At City of Hope, our team of pediatric experts provides comprehensive care for children with leukemia and lymphoma. Leukemia is a cancer of the blood and the most common cancer in children, accounting for approximately 40 percent of all cancer diagnoses in children. Lymphomas are cancers that develop in the body’s lymphatic system and are the third most common pediatric cancer, after leukemia and brain tumors. Our program treats patients with a range of leukemias and lymphomas, including:

Leukemias
 
  • Acute lymphoblastic leukemia (ALL)
  • Acute myeloid leukemia (AML)
  • Chronic myelogenous leukemia (CML)
     
Lymphomas
 
  • Hodgkin lymphoma
  • Non-Hodgkin lymphoma
    • Anaplastic large-cell lymphoma (ALCL)
    • B-cell lymphoma (Burkitt and Burkitt-like lymphoma)
    • Diffuse large B-cell lymphoma (DLBC)
    • Lymphoblastic lymphoma
    • T-cell lymphoma
    • MK-cell lymphoma
       
We treat newly diagnosed patients, as well as patients referred to us from other centers who come to City of Hope to continue their treatment, manage complications of treatment or develop new treatment strategies for cancers not responding to treatment, or for situations in which they have experienced a relapse. For children who fail to respond to treatment or experience a relapse, City of Hope has a renowned program in stem cell transplantation, as well as ongoing studies into novel therapies for relapsed/refractory leukemia.
 
Each type of childhood cancer is treated differently, based on what has been found to be most effective in destroying the particular type of cancer cell. The most common type of cancer treatment for leukemia and lymphoma is chemotherapy. In some cases, radiation therapy and/or stem cell transplant may be recommended. Immunotherapy, or treatment that uses certain parts of the immune system to fight cancer, may be used as well.

A unique benefit of being treated at City of Hope is that we treat young children, adolescents and young adults, ensuring a continuum of care through the years for this special group of patients. Adolescents and young adults may be eligible for clinical studies and novel treatments available for adult patients at City of Hope, while still benefitting from the patient and family-centered approach of the pediatric program.

Our program offers both outstanding medical treatment and psychosocial support to young cancer patients and their family members. Pediatric oncologists, hematologists, surgeons, radiation oncologists, pathologists and other specialists work in concert to develop a targeted, effective treatment plan.  At the same time, professionals in psychology; social work; child life; recreational, occupational and physical therapy; music therapy; and school reintegration provide individual attention and group activities for patients and their families.

Meet the members of City of Hope’s pediatric leukemia and lymphoma team:
 
The majority of children diagnosed with leukemia or lymphoma are cured; however, there can be long-term side effects. Our Center for Cancer Survivorship clinic is specially designed to meet the follow-up needs of childhood cancer survivors, who are evaluated annually by a team of health care professionals with expertise in survivorship issues.
 
Your child may have the opportunity to participate in a research study or clinical trial through our participation in the Children’s Oncology Group (COG) and our designation as one of only 41 National Cancer Institute (NCI) Comprehensive Cancer Centers in the U.S. More information about our pediatric cancer research, including ongoing clinical trials, is available on City of Hope’s Clinical Trials Online website.
 
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Meet City of Hope patients and their families.
 
 
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As a Comprehensive Cancer Center – the highest designation given by the National Cancer Institute – we are widely regarded as a leader in cancer prevention and treatment.

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NEWS & UPDATES
  • When Keith McKinny, 29, was first diagnosed with lymphoma and leukemia in 2010, the first person he thought of was former boyfriend Jason Mullins. The two hadn’t been in contact with each other for some time, but McKinny couldn’t think of anyone else with whom he wanted to be during that difficult period....
  • Yesenia Portillo’s search for a bone marrow donor started close to home. Her brother, sister and seven cousins all underwent testing, but none of them were a close enough match to donate the bone marrow stem cells she desperately needed for her transplant. Yesenia, now 16, had always been healthy and active. Bu...
  • Some of City of Hope’s most high-impact achievements have arisen from City of Hope’s globally recognized bone marrow transplant (BMT) program. The annual Karl G. Blume – Gerhard Schmidt Memorial Lecture in Transplantation Biology & Medicine — commemorating two of the most influential and revered...
  • Guido Marcucci, M.D., wants to put himself out of business. A respected clinician and esteemed basic and translational scientist, Marcucci joins City of Hope as co-director of the Gehr Family Center for Leukemia Research within the Hematologic Malignancies and Stem Cell Transplantation Institute. In this positi...
  • To say that myelofibrosis patients need more treatment options would be an understatement. The severely low platelet counts, known as thrombocytopenia, that are one of the hallmark symptoms of the disease can lead to chronic fatigue and weakness that not only damage quality of life but, ultimately, shorten life...
  • Patients with metastatic colorectal cancer often stop responding to the primary drugs used against the disease, leaving them with few options and little hope. Determined to increase those options, doctors and researchers at City of Hope are conducting two clinical trials that could lead to new treatments for pe...
  • Investigators working at City of Hope are making many significant inroads against many forms of cancer. To do that, they have to take a variety of approaches. Molecular oncology researchers focus on abnormal cancer-associated activity in a cell’s nucleus. One especially prominent factor in many breast and ovari...
  • In light of the new breast cancer screening guidelines, which call for women to have mammograms every other year from age 50 to 74, it’s more important than ever for women to understand their individual risk. On Monday, the U.S. Preventive Services Task force released new breast cancer screening guideline...
  • Cancer patients need, and deserve, more than medical care. They and their families need high-quality supportive care – that is, care that addresses their physical, emotional and spiritual well-being. Health care professionals increasingly understand this, but starting such programs from scratch isn’t easy...
  • Each year, City of Hope patients given another chance at life gather to pose for a picture like this one. Going on its 39th year, the celebration of patients free of blood cancers thanks to bone marrow or stem cell transplants has grown such that a photographer has to scale a cherry picker just to […]
  • Cancer patients who are participating in early-stage clinical trials need extra emotional and physical support due to their additional stress and often unique symptoms. Now an effort by researchers at City of Hope to create a model for such support has received a $6.8 million grant from the National Cancer Inst...
  • The need for improvements in treating malignant brain tumors has never been greater. Survival for many patients with these tumors are sometimes measured in just months. One reason that therapeutic options are limited is that traditional surgery is deemed too risky for many brain tumors, especially for those in ...
  • “Honestly, there’s nothing special about my story,” protested Daniel Samson, as he bounced Layla, his 3 1/2-year-old daughter, on his lap and put on a video for her to watch. “I just want to tell it for my own sake, and share it with other men who may be going through this chaos.” Samson spoke […]
  • As far back as he can remember, Jonathan Yamzon, M.D., wanted to be a doctor. “I knew it from the get-go,” he said, matter-of-factly. “I always envisioned it as the ideal; the supreme thing one could do with one’s life.” The youngest of six children, Yamzon was barely a toddler when his family moved to [&...
  • There’s never a “good” time for cancer to strike. With testicular cancer, the timing can seem particularly unfair. This disease targets young adults in the prime of life; otherwise healthy people unaccustomed to any serious illness, let alone cancer. And suddenly … “I can only imagine what they must...