Battling the complications of diabetes
Gene and cell-based therapies
Islet encapsulation and isolation
Islet isolation and distribution
Islet quality assessment
New drug discoveries
Stem cell biology and development
Researchers in the Division of Developmental & Translational Diabetes and Endocrine Research and the Division of Molecular Diabetes Research:
Ismail Al-Abdullah, Ph.D.: Islet cell isolation.
Sanjay Awasthi, M.D.: Diabetes and cancer.
Kevin Ferreri, Ph.D.: Islet cell transplantation; epigenetics; and diabetic biomarkers.
Wendong Huang, Ph.D.: Genetic and epigenetic regulation of diabetes; stem cell and drug development for diabetes.
Janice Huss, Ph.D.: Characterization of transcriptional mechanisms regulating skeletal muscle metabolic adaptations during growth and differentiation and in response to physiologic stress; an the etiologic role of orphan nuclear receptors in obesity and type 2 diabetes.
Fouad R. Kandeel, M.D., Ph.D.: Islet cell transplantation.
Hsun Teresa Ku, Ph.D.: In vitro differentiation of human and mouse embryonic stem cells towards pancreatic lineage cells; and identification, purification and characterization of embryonic and adult pancreatic stem/progenitor cells.
Chih-Pin Liu, Ph.D.: Development of methods to induce immune tolerance; identification of novel cellular and molecular targets to improve cell-based therapy for diabetes.
Yoko Mullen, M.D., Ph.D.: Extrahepatic islet transplantation; and prevention of islet loss for transplantation.
Rama Natarajan, Ph.D.: Identification of the molecular mechanisms underlying the accelerated cardiovascular and renal disease observed in diabetic patients and in obese subjects; role of epigenetics and microRNAs, and other non-coding RNAs; and inflammatory responses in islet destruction.
Defu Zeng, M.D.: Induction of mixed chimerism for reversal of autoimmunity; beta cell regeneration; and transplantation immune tolerance.