A National Cancer Institute-designated Comprehensive Cancer Center

Make an appointment: 800-826-HOPE
Clinical Research Training Office Bookmark and Share

Clinical Research Training Office

The Clinical Research Training Office (CRTO) provides comprehensive training in clinical research, good clinical practice, and responsible conduct of research. Didactic instruction and mentoring in fundamental skills, methodology, good clinical practice, and theory of clinical research all combine to develop a well-trained, independent, clinical investigator.
 
Our mission is to bridge the gap between the basic scientist and clinician, to streamline the development of novel therapeutics, and facilitate their application in clinical trials. City of Hope’s dual strengths in breakthrough biomedical research and compassionate patient care form the basis for our comprehensive approach, educating students, residents, fellows, and faculty in practical applications of scientific knowledge, for the treatment of patients everywhere.
 
All City of Hope personnel involved with human subject research at City of Hope must have a valid Clinical Research Certification. Recertification must be updated every three years through the Clinical Research Training Office. City of Hope and Beckman Research Institute are committed to ensuring the safe and ethical conduct of research involving human subjects and adhering to federal and state regulations and statutes.
 
City of Hope’s Clinical Investigation Training Program (CITP) provides scholars with clinical research fundamentals and the comprehensive skill set required for today's comprehensive clinical investigator.
 
For additional information, please contact the Clinical Research Training Office at ext. 64496.

Welcome from the Director

Welcome to the City of Hope Clinical Research Training Office, which was developed to institute formal training opportunities in clinical research. Our vision is to bring basic scientists and clinicians together to better facilitate the bench-to-bedside continuum.
 
One function of the office is the Clinical Investigation Training Program (CITP), which provides didactic training and mentoring in the principles of clinical research including development of fundamental skills, methodology, and theory, necessary for today’s well-trained, independent, clinical investigator.
 
Building on City of Hope’s strength in cutting edge research and patient care, we developed the program’s comprehensive curriculum to provide professionals with the necessary tools to perform valid, credible patient-based research for the advancement of scientific knowledge and treatment of human disease.
 
I invite you to explore our multidisciplinary program and the various options available to advance your clinical research training and career development.
 
Jonathan Espenschied
Director
 
 

Clinical Investigation Training Program (CITP) Leadership

CITP Faculty and Mentors

The Clinical Investigation Training Program’s faculty members are nationally-renowned scholars and researchers who are experts in teaching and conducting research. Our multidisciplinary faculty members hail from the world’s most prestigious universities and research institutions, and are the recipients of numerous awards and accolades.  City of Hope’s intimate and collegial environment allows faculty members to be effective mentors to program participants, leading them down the path to professional clinical researcher.

Career Development Programs

City of Hope's Clinical Research Training Office actively assists physicians and scientists in fulfilling their career aspirations. These programs, housed on the City of Hope campus, provide excellent opportunities for those seeking to further their career in cancer research and treatment.
 
 
City of Hope is proud to be one of only two National Cancer Institute (NCI)-designated Cancer Centers that have offered this National Institutes of Health (NIH)-sponsored program. The intensive curriculum, aimed at physicians interested in a research-focused career, includes didactic and laboratory experiences relevant to the candidates’ academic background while developing new skills necessary for the demanding role of the physician investigator.
 
Growing awareness of the genetic etiology of many types of cancer has driven City of Hope’s NCI-designated Comprehensive Cancer Center to offer the innovative Cancer Genetics Career Development Program. The program provides rigorous interdisciplinary training focused on cancer genetics as well as cancer prevention research. This prestigious traineeship is limited to only three participants per year.
 

City of Hope Resources

BITS: Building Information Technology Skills - tools for clinical researchers
 
Bioinformatics Core (BIC) Facility
Features information on current projects within the division; provides DNA sequencing resources
 
Clinical Trials On-Line
Comprehensive database of clinical trials at
 
The operating procedures site for City of Hope’s Department of Biostatistics

Rules and regulations of City of Hope/Beckman Research Institute’s IRB and Human Subject Research Guidelines
 
Allows authorized user access to the department’s Citrix Web portal
 

 

 

CRTO Glossary

The field of clinical investigation has a language all its own, replete with acronyms and jargon. The Clinical Research Training Office staff has put together the following compendium of commonly used terminology in clinical research.

Clinical Research Training Office

Clinical Research Training Office

The Clinical Research Training Office (CRTO) provides comprehensive training in clinical research, good clinical practice, and responsible conduct of research. Didactic instruction and mentoring in fundamental skills, methodology, good clinical practice, and theory of clinical research all combine to develop a well-trained, independent, clinical investigator.
 
Our mission is to bridge the gap between the basic scientist and clinician, to streamline the development of novel therapeutics, and facilitate their application in clinical trials. City of Hope’s dual strengths in breakthrough biomedical research and compassionate patient care form the basis for our comprehensive approach, educating students, residents, fellows, and faculty in practical applications of scientific knowledge, for the treatment of patients everywhere.
 
All City of Hope personnel involved with human subject research at City of Hope must have a valid Clinical Research Certification. Recertification must be updated every three years through the Clinical Research Training Office. City of Hope and Beckman Research Institute are committed to ensuring the safe and ethical conduct of research involving human subjects and adhering to federal and state regulations and statutes.
 
City of Hope’s Clinical Investigation Training Program (CITP) provides scholars with clinical research fundamentals and the comprehensive skill set required for today's comprehensive clinical investigator.
 
For additional information, please contact the Clinical Research Training Office at ext. 64496.

Welcome from the Director

Welcome from the Director

Welcome to the City of Hope Clinical Research Training Office, which was developed to institute formal training opportunities in clinical research. Our vision is to bring basic scientists and clinicians together to better facilitate the bench-to-bedside continuum.
 
One function of the office is the Clinical Investigation Training Program (CITP), which provides didactic training and mentoring in the principles of clinical research including development of fundamental skills, methodology, and theory, necessary for today’s well-trained, independent, clinical investigator.
 
Building on City of Hope’s strength in cutting edge research and patient care, we developed the program’s comprehensive curriculum to provide professionals with the necessary tools to perform valid, credible patient-based research for the advancement of scientific knowledge and treatment of human disease.
 
I invite you to explore our multidisciplinary program and the various options available to advance your clinical research training and career development.
 
Jonathan Espenschied
Director
 
 

Leadership

Clinical Investigation Training Program (CITP) Leadership

Faculty and Mentors

CITP Faculty and Mentors

The Clinical Investigation Training Program’s faculty members are nationally-renowned scholars and researchers who are experts in teaching and conducting research. Our multidisciplinary faculty members hail from the world’s most prestigious universities and research institutions, and are the recipients of numerous awards and accolades.  City of Hope’s intimate and collegial environment allows faculty members to be effective mentors to program participants, leading them down the path to professional clinical researcher.

Career Development Programs

Career Development Programs

City of Hope's Clinical Research Training Office actively assists physicians and scientists in fulfilling their career aspirations. These programs, housed on the City of Hope campus, provide excellent opportunities for those seeking to further their career in cancer research and treatment.
 
 
City of Hope is proud to be one of only two National Cancer Institute (NCI)-designated Cancer Centers that have offered this National Institutes of Health (NIH)-sponsored program. The intensive curriculum, aimed at physicians interested in a research-focused career, includes didactic and laboratory experiences relevant to the candidates’ academic background while developing new skills necessary for the demanding role of the physician investigator.
 
Growing awareness of the genetic etiology of many types of cancer has driven City of Hope’s NCI-designated Comprehensive Cancer Center to offer the innovative Cancer Genetics Career Development Program. The program provides rigorous interdisciplinary training focused on cancer genetics as well as cancer prevention research. This prestigious traineeship is limited to only three participants per year.
 

Helpful Links and Resources

City of Hope Resources

BITS: Building Information Technology Skills - tools for clinical researchers
 
Bioinformatics Core (BIC) Facility
Features information on current projects within the division; provides DNA sequencing resources
 
Clinical Trials On-Line
Comprehensive database of clinical trials at
 
The operating procedures site for City of Hope’s Department of Biostatistics

Rules and regulations of City of Hope/Beckman Research Institute’s IRB and Human Subject Research Guidelines
 
Allows authorized user access to the department’s Citrix Web portal
 

 

 

CRTO Quick Links

CRTO Quick Links

Learn About Clinical Trials
National Cancer Institute (NCI)-provided resource about the clinical trial process

Common Terminology Criteria for Adverse Events

Code of Federal Regulations (CFR)
Codification of the general and permanent rules published in the Federal Register

FDA Running Clinical Trials

Food and Drug Administration

Grant Writing Tip Sheets
National Institutes of Health (NIH) provides these helpful tips for writing grants that get funded

Intro to Extramural Research
A helpful page from NIH’s Office of Extramural Research with staff directory and organizational charts

Inside the NIH grant review process (video)

National Institutes of Health (NIH)

National Library of Medicine
 
NCI Guidelines and Tools for Protocol Development

Office of Research Integrity (ORI)
A resource promoting integrity in biomedical and behavioral research

SoCRA
Professional Membership Organization that provides continuing education for Clinical Research Associates

R-Statisitical Software

Tutorials “All about Grants”
A thorough, step-by step tutorial provided by NIH; very helpful for first-time grant writers

Writing Plain Language Protocols
Good scientific writing is moving away from jargon and toward plain language; this guide tells you more
 
 

CRTO Glossary

CRTO Glossary

The field of clinical investigation has a language all its own, replete with acronyms and jargon. The Clinical Research Training Office staff has put together the following compendium of commonly used terminology in clinical research.
Education and Training
As one of only a select few National Cancer Institute-designated Comprehensive Cancer Centers in the country, City of Hope integrates all aspects of cancer research, treatment and education. We offer a range of programs serving students, post-doctoral trainees, health and medical professionals.

City of Hope’s Irell & Manella Graduate School of Biological Sciences equips students with the skills and strategies to transform the future of modern medicine.
City of Hope has a long-standing commitment to Continuing Medical Education (CME), sharing advances in cancer research and treatment with the health-care community through CME courses such as conferences, symposia and other on and off campus CME opportunities for medical professionals.
Local and national conferences, in-depth educational training and a certification program provide both current and aspiring health professionals opportunities to further their knowledge in their fields of interest.
 
 
City of Hope offers a range of programs and services, such as Graduate Medical Education & Clinical Training, that serve students, post-doctoral trainees, medical professionals and staff.
The goal of the Postdoctoral Training Office is to ensure the postdoctoral experience at City of Hope is rewarding and meaningful to all participants.


NEWS & UPDATES
  • Internship programs are a rite of summer for many high-achieving students. For five Caltech pre-med students, each hoping to make a mark in medicine, that rite led them to the City of Hope campus in Duarte, California, for an exceptional learning experience. The collaboration between the two high-profile resear...
  • Urinary tract stones are hard masses, or calculi, that form in the urinary tract and may cause pain, bleeding or an infection, or even block of the flow of urine. Urinary tract stones begin to form in a kidney and may enlarge in a ureter or the bladder. Depending on where a stone is located, […]
  • Every summer, hospitals nationwide experience a shortage of blood donations. This summer is no exception. Nearly 1.7 million new cancer cases are expected to be diagnosed in the U.S. this year,  and many of those patients will need blood transfusions during their treatment. Patients at City of Hope alone rely o...
  • Non-Hodgkin lymphoma facts: Non-Hodgkin lymphoma is a cancer that starts in cells called lymphocytes, which are part of the body’s immune system. Lymphocytes are in the lymph nodes and other lymphoid tissues (such as the spleen and bone marrow). Non-Hodgkin lymphoma is one of the most common cancers in the U.S....
  • Few clinical cancer trials include older adults – and yet, more than 60 percent of cancer cases in the United States occur in people age 65 and older. The result is a dearth of knowledge on how to treat the very population most likely to be diagnosed with cancer. Now, the American Society of Clinical […]
  • Scientists at City of Hope and UCLA have become the first to inhibit the expression of a protein, called TWIST that promotes tumor invasion and metastasis when activated by cancer cells. As such, they’ve taken the first step in developing a potential new therapy for some of the deadliest cancers, including ovar...
  • Upon completing her final round of chemotherapy for ovarian cancer earlier this month, Maria Velazquez-McIntyre, a 51-year-old Antelope Valley resident, celebrated the milestone by giving other patients a symbol of hope – a Survivor Bell. The bell may look ordinary, but for cancer patients undergoing chemothera...
  • Many Americans understand that obesity is tied to heart disease and diabetes but, according to a new survey, too few – only 7 percent – know that obesity increases the risk of cancer. Specific biological characteristics can increase cancer risk in obese people, and multiple studies have shown correlations betwe...
  • As breast cancer survivors know, the disease’s impact lingers in ways both big and small long after treatment has ended. A new study suggests that weight gain – and a possible corresponding increase in heart disease and diabetes risk – may be part of that impact. In the first study to evaluate weight chan...
  • Becoming what’s known as an independent scientific researcher is no small task, especially when working to translate research into meaningful health outcomes. Yet that independent status is vital, enabling researchers to lead studies and avenues of inquiry that they believe to be promising. Clinicians, especial...
  • 720 days. That’s how long Alex Tung, 38, had to give up surfing after being diagnosed with acute myeloid leukemia. For most people, even some surfers, such a hiatus wouldn’t be a big deal, but for Tung, surfing has been everything. The Southern California resident began surfing when he was in elemen...
  • There are few among us who have not experienced loss of a friend or loved one, often without warning, or like those of us who care for people with cancer, after a lingering illness. It is a time when emotions run high and deep, and as time passes from the moment of loss, we often […]
  • For the past four years, neurosurgeon and scientist Rahul Jandial, M.D., Ph.D., has been studying how breast cancer cells spread, or metastasize, to the brain, where they become life-threatening tumors. Known as secondary brain tumors, these cancers have become increasingly common as treatment advances have ena...
  • Cutaneous T cell lymphomas are types of non-Hodgkin lymphoma that arise when infection-fighting white blood cells in the lymphatic system – called lymphocytes – become malignant and affect the skin. A primary symptom is a rash that arises initially in areas of the skin that are not normally exposed to sunlight....
  • There’s science camp, and then there’s “mystery” science camp. City of Hope’s new science camp for middle school students is of the especially engaging latter variety. From Monday, July 13, to Friday, July 17, rising middle-school students from across the San Gabriel Valley were presented with a “patient” with ...