A National Cancer Institute-designated Comprehensive Cancer Center

Make an appointment: 800-826-HOPE
Clinical Protocol & Data Management Core (CPDMC) Bookmark and Share

Clinical Protocol & Data Managment Core (CPDMC)

Co-Director: Adina Londrc, M.D.
Co-Director: Ajay Shah, Ph.D.
Core Managers: Karen Rickard & Gabe Peterson


The Clinical Protocol and Data Management Core (CPDMC) is led by Adina Londrc, M.D. (Director of Clinical Research Information Support), and Ajay Shah, Ph.D. (Director of Research Informatics) with Karen Rickard and Gabe Peterson serving as Core Managers. The Core provides centralized infrastructure and support for effective, efficient conduct of clinical research.

The CPDMC offers comprehensive services to COH Cancer Center members including: protocol document management, electronic data capture, standardized clinical research staff training and education, honest broker process for accessing tissue samples, study recruitment tracking, patient safety decision support tools, data quality assurance and monitoring, multi-site coordination, and customized and routine reports.
 
CPDMC Core Services
Protocol Management
 
  • Protocol Document Management, i.e. Clinical Trials On-lineSM
  • Clinical Trials Reporting Program (CTRP) Reporting
  • Clinical Trials Management Systems
  • Research Informatics Architecture

Electronic Data Capture
 
  • Case Report FormDevelopment
  • Data Collection Grid Creation
  • Forms Instructions
  • Metadata Management
  • Electronic Case Report Form Construction
  • Laboratory Data Capture
  • Enterprise Data Warehouse

Training
 
  • Protocol Management Training
  • Case Report Form Training
  • Training Workshops & In-Services
  • Training Tools and Manuals
  • E-Learning
  • Communities of Practice

Study Recruitment Management
 
  • Subject Registration
  • Accrual Monitoring
  • Online Subject Registration
  • Online Informed Consent Linkage

Study Conduct Management
 
  • Data Quality Monitoring
  • Multi-Site Coordination
  • Audit Preparation
  • Programmatic Edit Checks
  • Subject Safety Decision Support

Reporting and Analysis Support
 
  • Monitoring & Validating Accruals
  • Data Curation for Statistical Analysis
  • Database Lock
  • Decision Support
  • Data Mart Creation
  • Online Informed Consent Linkage

Data Integration Querying
 
  • De-identified Cohort Discovery (iCoDE)
  • Cancer Registry Data
  • Diagnosis and Procedures
  • Tissue Specimen Information
 

Abstract for Grants

The Clinical Protocol and Data Management Core (CPDMC) is a collaborative integrated unit staffed by professionals with expertise in protocol data management and clinical research informatics, to provide centralized infrastructure and support for the effective efficient conduct of clinical research. Working closely with the Biostatistics Core, this team blends technical and scientific expertise to provide City of Hope investigators with world-class research support and informatics solutions for clinical trials, observational studies, and outcomes research. The CPDMC offers comprehensive services to COH Cancer Center members including: protocol document management, electronic data capture, standardized clinical research staff training and education, honest broker process for accessing tissue samples, study recruitment tracking, patient safety decision support tools, data quality assurance and monitoring, multi-site coordination, and customized and routine reports.
 
The CPDMC provides input into developing protocols with respect to practicality and appropriateness of protocol management, study calendar, and data collection issues. Data Quality Monitors ensure that study research staff are fully trained in protocol management, data collection, and overall study conduct according to Good Clinical Practice (GCP) and COH policies. The CPDMC database monitors ensure that protocol and patient registration is carried out according to NCI guidelines.
 
Key informatics services provided include: Clinical Trial Management Systems to manage planning, execution, and reporting of clinical research studies; Electronic Data Capture to provide electronic case report forms; and Clinical Research Decision Support to translate data into scientific decisions. Our emerging work on Translational Research Informatics includes implementation of the enterprise data warehouse, i2b2 open source system for cohort selection for tissue correlative studies, along with Electronic Lab Notebook and Laboratory Information Management Systems.
 
For all these functions we use international architectural and vocabulary standards and project management methodologies to deliver clinical and translational informatics applications. In summary, the CPDMC delivers resources, education, and information management processes to establish best practices in accordance with FDA, GCP, regulatory requirements such as 21CFR Part 11, and international data standards such as HL7, SNOMED, and LOINC.

Pricing

Pricing

Prices and availability vary. Please Contact Us for current information.

Comprehensive Cancer Center
In recognition of our excellence in a broad range of new approaches to cancer research and treatment—and our outreach to the community— the National Cancer Institute (NCI) has designated City of Hope a Comprehensive Cancer Center—one of just a handful of elite institutions nationwide.

Using the Facility

The Core's services are available to all City of Hope faculty, with City of Hope Cancer Center members receiving the highest priority.

To request service or discuss how we can facilitate your scientific goals, please Contact Us.
 

Clinical Protocol & Data Managment Core Team

Clinical Protocol & Data Management Core (CPDMC)

Clinical Protocol & Data Managment Core (CPDMC)

Co-Director: Adina Londrc, M.D.
Co-Director: Ajay Shah, Ph.D.
Core Managers: Karen Rickard & Gabe Peterson


The Clinical Protocol and Data Management Core (CPDMC) is led by Adina Londrc, M.D. (Director of Clinical Research Information Support), and Ajay Shah, Ph.D. (Director of Research Informatics) with Karen Rickard and Gabe Peterson serving as Core Managers. The Core provides centralized infrastructure and support for effective, efficient conduct of clinical research.

The CPDMC offers comprehensive services to COH Cancer Center members including: protocol document management, electronic data capture, standardized clinical research staff training and education, honest broker process for accessing tissue samples, study recruitment tracking, patient safety decision support tools, data quality assurance and monitoring, multi-site coordination, and customized and routine reports.
 
CPDMC Core Services
Protocol Management
 
  • Protocol Document Management, i.e. Clinical Trials On-lineSM
  • Clinical Trials Reporting Program (CTRP) Reporting
  • Clinical Trials Management Systems
  • Research Informatics Architecture

Electronic Data Capture
 
  • Case Report FormDevelopment
  • Data Collection Grid Creation
  • Forms Instructions
  • Metadata Management
  • Electronic Case Report Form Construction
  • Laboratory Data Capture
  • Enterprise Data Warehouse

Training
 
  • Protocol Management Training
  • Case Report Form Training
  • Training Workshops & In-Services
  • Training Tools and Manuals
  • E-Learning
  • Communities of Practice

Study Recruitment Management
 
  • Subject Registration
  • Accrual Monitoring
  • Online Subject Registration
  • Online Informed Consent Linkage

Study Conduct Management
 
  • Data Quality Monitoring
  • Multi-Site Coordination
  • Audit Preparation
  • Programmatic Edit Checks
  • Subject Safety Decision Support

Reporting and Analysis Support
 
  • Monitoring & Validating Accruals
  • Data Curation for Statistical Analysis
  • Database Lock
  • Decision Support
  • Data Mart Creation
  • Online Informed Consent Linkage

Data Integration Querying
 
  • De-identified Cohort Discovery (iCoDE)
  • Cancer Registry Data
  • Diagnosis and Procedures
  • Tissue Specimen Information
 

Abstract for Grants

Abstract for Grants

The Clinical Protocol and Data Management Core (CPDMC) is a collaborative integrated unit staffed by professionals with expertise in protocol data management and clinical research informatics, to provide centralized infrastructure and support for the effective efficient conduct of clinical research. Working closely with the Biostatistics Core, this team blends technical and scientific expertise to provide City of Hope investigators with world-class research support and informatics solutions for clinical trials, observational studies, and outcomes research. The CPDMC offers comprehensive services to COH Cancer Center members including: protocol document management, electronic data capture, standardized clinical research staff training and education, honest broker process for accessing tissue samples, study recruitment tracking, patient safety decision support tools, data quality assurance and monitoring, multi-site coordination, and customized and routine reports.
 
The CPDMC provides input into developing protocols with respect to practicality and appropriateness of protocol management, study calendar, and data collection issues. Data Quality Monitors ensure that study research staff are fully trained in protocol management, data collection, and overall study conduct according to Good Clinical Practice (GCP) and COH policies. The CPDMC database monitors ensure that protocol and patient registration is carried out according to NCI guidelines.
 
Key informatics services provided include: Clinical Trial Management Systems to manage planning, execution, and reporting of clinical research studies; Electronic Data Capture to provide electronic case report forms; and Clinical Research Decision Support to translate data into scientific decisions. Our emerging work on Translational Research Informatics includes implementation of the enterprise data warehouse, i2b2 open source system for cohort selection for tissue correlative studies, along with Electronic Lab Notebook and Laboratory Information Management Systems.
 
For all these functions we use international architectural and vocabulary standards and project management methodologies to deliver clinical and translational informatics applications. In summary, the CPDMC delivers resources, education, and information management processes to establish best practices in accordance with FDA, GCP, regulatory requirements such as 21CFR Part 11, and international data standards such as HL7, SNOMED, and LOINC.

Pricing

Pricing

Pricing

Prices and availability vary. Please Contact Us for current information.

Comprehensive Cancer Center
In recognition of our excellence in a broad range of new approaches to cancer research and treatment—and our outreach to the community— the National Cancer Institute (NCI) has designated City of Hope a Comprehensive Cancer Center—one of just a handful of elite institutions nationwide.

Using the Facility

Using the Facility

The Core's services are available to all City of Hope faculty, with City of Hope Cancer Center members receiving the highest priority.

To request service or discuss how we can facilitate your scientific goals, please Contact Us.
 

Clinical Protocol & Data Managment Core Team

Clinical Protocol & Data Managment Core Team

Research Shared Services

City of Hope embodies the spirit of scientific collaboration by sharing services and core facilities with colleagues here and around the world.
 

Recognized nationwide for its innovative biomedical research, City of Hope's Beckman Research Institute is home to some of the most tenacious and creative minds in science.
City of Hope is one of only 41 Comprehensive Cancer Centers in the country, the highest designation awarded by the National Cancer Institute to institutions that lead the way in cancer research, treatment, prevention and professional education.
Learn more about City of Hope's institutional distinctions, breakthrough innovations and collaborations.
Support Our Research
By giving to City of Hope, you support breakthrough discoveries in laboratory research that translate into lifesaving treatments for patients with cancer and other serious diseases.
 
 
 
 
Media Inquiries/Social Media

For media inquiries contact:

Dominique Grignetti
800-888-5323
dgrignetti@coh.org

 

For sponsorships inquiries please contact:

Stefanie Sprester
213-241-7160
ssprester@coh.org

Christine Nassr
213-241-7112
cnassr@coh.org

 
CONNECT WITH US
Facebook  Twitter  YouTube  Blog
 
NEWS & UPDATES
  • Advances in cancer treatment, built on discoveries made in the laboratory then brought to the bedside, have phenomenally changed the reality of living with a cancer diagnosis. More than any other time in history, people diagnosed with cancer are more likely to survive and to enjoy a high quality of life. Howeve...
  • While health care reform has led to an increase in the number of people signing up for health insurance, many people remain uninsured or are not taking full advantage of the health benefits they now have. Still others are finding that, although their premiums are affordable, they aren’t able to see the do...
  • Kidney cancer rates and thyroid cancer rates in adults have continued to rise year after year. Now a new study has found that incidence rates for these cancers are also increasing in children — particularly in African-American children. The study, published online this month in Pediatrics, examined childhood ca...
  • Thyroid cancer has become one of the fastest-growing cancers in the United States for both men and women. The chance of being diagnosed with the cancer has nearly doubled since 1990. This year an estimated 63,000 people will be diagnosed with thyroid cancer in the United States and nearly 1,900 people will die ...
  • Older teenagers and young adults traditionally face worse outcomes than younger children when diagnosed with brain cancer and other central nervous system tumors. A first-of-its-kind study shows why. A team of researchers from the departments of Population Sciences and Pathology at City of Hope recently examine...
  • Cancer treatment can take a toll on the mouth, even if a patient’s cancer has nothing to do with the head or throat, leading to a dry mouth, or a very sore mouth, and making it difficult to swallow or eat. Here’s some advice from the National Cancer Institute (NCI)  on how to ease cancer-related dis...
  • Radiation oncology is one of the three main specialties involved in the successful treatment of cancer, along with surgical oncology and medical oncology. Experts in this field, known as radiation oncologists, advise patients as to whether radiation therapy will be useful for their cancer – and how it can best ...
  • There’s more to cancer care than simply helping patients survive. There’s more to cancer treatment than simple survival. Constant pain should not be part of conquering cancer,  insists Betty Ferrell, Ph.D., R.N., director of nursing research and education at City of Hope. She wants patients and caregivers...
  • Even its name is daunting. Systemic mastocytosis is a fatal disease of the blood with no known cure. But a new study suggests a bone marrow transplant may be the answer for some patients. While rare, systemic mastocytosis is resistant to treatment with drugs and, when aggressive, can be fatal within four years ...
  • Could what you eat affect the health of your chromosomes? The short answer is, “Yes.” Researchers led by Dustin Schones, Ph.D., assistant professor in the Department of Cancer Biology, and Rama Natarajan, Ph.D., director of the Division of Molecular Diabetes Research and the National Business Products Industry ...
  • September is Prostate Cancer Awareness Month. Here, Bertram Yuh, M.D., assistant clinical professor in the Division of Urology and Urologic Oncology at City of Hope, explains the importance of understanding the risk factors for the disease and ways to reduce those risks, as well as overall prostate health. “Wha...
  • ** Learn more about prostate health, plus prostate cancer research and treatment, at City of Hope. ** Learn more about getting a second opinion at City of Hope by visiting us online or by calling 800-826-HOPE (4673). City of Hope staff will explain what’s required for a consult at City of Hope and help yo...
  • Childhood cancer survival rates have increased dramatically over the past 40 years. More than 80 percent of children with cancer now survive five years or more, which is a tremendous feat. Despite the survival rate increase, cancer continues to be the No. 1 disease killer and second-leading cause of death in ch...
  • Although a stem cell transplant can be a lifesaving procedure for people diagnosed with a blood cancer or blood disorder, the standard transplant may not be appropriate for all patients. This is because the conditioning regimen (the intensive chemotherapy and/or radiation treatments preceding the transplant) is...
  • Brain tumor removal would seem to be the obvious course of action in the wake of a brain tumor diagnosis, but that’s not always the case. Some tumors are too difficult for many surgeons to reach or too close to areas that control vital functions. Removing them just proves too risky. A new device being con...