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Clinical Investigation Training Program

The Clinical Investigation Training Program (CITP) is committed to addressing the critical need for formal training and advancement in clinical research, as well as increasing the quantity, and more importantly, quality of well trained clinical investigators. The ultimate goal is to provide clinical research education, guided by apatient-centered philosophy, which will have a significant impact on cancer and other life-threatening diseases.
 
City of Hope's Clinical Investigation Training Program (CITP) is dedicated to a core group of objectives. Among these are:
  • Provide high-quality, multidisciplinary services to our scholars
     
  • Address the critical need for formal training and advancement in clinical investigation as well as increase the quantity and, more importantly, quality of well-trained clinical investigators.
     
  • Facilitate, through intensive mentoring, the transition fromscholar to independent clinical investigator
     
  • Bring City of Hope scientists and clinicians closer together to facilitate the bench-to-bedside continuum
     

CITP Core Curriculum

Core Curriculum
The City of Hope Clinical Investigation Training Program (CITP) is a yearlong (4 quarter) curriculum designed to present the principles and practices used in the planning and execution of patient-oriented research including principles and methods in biostatistics, clinical epidemiology, clinical trial development, ethics, and good clinical practices of research. Each course can be taken in any order throughout the year. A certificate in Clinical Research is awarded to scholars successfully completing the Program.
 
Methodology in Observational Studies CI510 (Fall) - Design & Analysis of Observational Research
Provides an overview of epidemiologic methods and their application to observational studies. Scholars will develop/enhance their ability to evaluate observational studies, including the adequacy of study design and the validity of stated conclusions. Scholars will also acquire the necessary conceptual frameworkto plan an observational study in collaboration with a statistical co-investigator.
 
Methodology in Therapeutic Studies CI520 (Winter) - Design& Analysis of Intervention Research
Provides anintroduction to the concepts, theory, and application of interventional clinical trials and the statistics commonly used to analyze these studies. This is a Biostatistics/Clinical Investiagation course that builds on basic background of biostatistics, and introductory clinical trials. This course will explore the fundamentals of clinical investigation including: the definition of study goals, application and theory, objectives and outcomes, trial design and outcome monitoring, and result reporting, as well as a brief review of the underlying statistical methods.
 
Study Design & Development CI530 (Spring) - Design & Development of Human Subject Research
Provides a review of the clinical study process as well as continued instruction in trial development. Scholars will experience the "Nuts and Bolts" of a clinical study, from submission, to committee review, activation, and monitoring. Each scholar will actively participate in the submission of a "mock" clinical protocol. The proper design, conduct, and analysis of a clinical study are imperative to the well being of each participant as well as the integrity of the study results. Responsible conduct of research and good clinical practice will be emphasized throughout the course as they are the cornerstones to an effective and efficient clinical study.
 
Scientific Writing & Evaluation CI550/1 (Summer)
This course will alternate yearly, and address topics in protocol writing and development (CI550) and career development awards (CI551). The emphasis of CI550 will be on developing a complete and feasible protocol leading to an efficient, effective clinical study. The classes will combine didactic instruction with small group discussions and "hands on" learning. The emphasis of CI551 will be on early career advancement, competitivegrant writing, and literature evaluation. This course will focus on developing a fundable, career development award suitable for peer review. Evaluations will be through oral presentations and a completed career development application.
 

Clinical Investigation Training Program (CITP) Leadership

CITP Faculty and Mentors

The Clinical Investigation Training Program’s faculty members are nationally-renowned scholars and researchers who are experts in teaching and conducting research. Our multidisciplinary faculty members hail from the world’s most prestigious universities and research institutions, and are the recipients of numerous awards and accolades.  City of Hope’s intimate and collegial environment allows faculty members to be effective mentors to program participants, leading them down the path to professional clinical researcher.

Clinical Investigation Training Program

Clinical Investigation Training Program

The Clinical Investigation Training Program (CITP) is committed to addressing the critical need for formal training and advancement in clinical research, as well as increasing the quantity, and more importantly, quality of well trained clinical investigators. The ultimate goal is to provide clinical research education, guided by apatient-centered philosophy, which will have a significant impact on cancer and other life-threatening diseases.
 
City of Hope's Clinical Investigation Training Program (CITP) is dedicated to a core group of objectives. Among these are:
  • Provide high-quality, multidisciplinary services to our scholars
     
  • Address the critical need for formal training and advancement in clinical investigation as well as increase the quantity and, more importantly, quality of well-trained clinical investigators.
     
  • Facilitate, through intensive mentoring, the transition fromscholar to independent clinical investigator
     
  • Bring City of Hope scientists and clinicians closer together to facilitate the bench-to-bedside continuum
     

CITP Core Curriculum

CITP Core Curriculum

Core Curriculum
The City of Hope Clinical Investigation Training Program (CITP) is a yearlong (4 quarter) curriculum designed to present the principles and practices used in the planning and execution of patient-oriented research including principles and methods in biostatistics, clinical epidemiology, clinical trial development, ethics, and good clinical practices of research. Each course can be taken in any order throughout the year. A certificate in Clinical Research is awarded to scholars successfully completing the Program.
 
Methodology in Observational Studies CI510 (Fall) - Design & Analysis of Observational Research
Provides an overview of epidemiologic methods and their application to observational studies. Scholars will develop/enhance their ability to evaluate observational studies, including the adequacy of study design and the validity of stated conclusions. Scholars will also acquire the necessary conceptual frameworkto plan an observational study in collaboration with a statistical co-investigator.
 
Methodology in Therapeutic Studies CI520 (Winter) - Design& Analysis of Intervention Research
Provides anintroduction to the concepts, theory, and application of interventional clinical trials and the statistics commonly used to analyze these studies. This is a Biostatistics/Clinical Investiagation course that builds on basic background of biostatistics, and introductory clinical trials. This course will explore the fundamentals of clinical investigation including: the definition of study goals, application and theory, objectives and outcomes, trial design and outcome monitoring, and result reporting, as well as a brief review of the underlying statistical methods.
 
Study Design & Development CI530 (Spring) - Design & Development of Human Subject Research
Provides a review of the clinical study process as well as continued instruction in trial development. Scholars will experience the "Nuts and Bolts" of a clinical study, from submission, to committee review, activation, and monitoring. Each scholar will actively participate in the submission of a "mock" clinical protocol. The proper design, conduct, and analysis of a clinical study are imperative to the well being of each participant as well as the integrity of the study results. Responsible conduct of research and good clinical practice will be emphasized throughout the course as they are the cornerstones to an effective and efficient clinical study.
 
Scientific Writing & Evaluation CI550/1 (Summer)
This course will alternate yearly, and address topics in protocol writing and development (CI550) and career development awards (CI551). The emphasis of CI550 will be on developing a complete and feasible protocol leading to an efficient, effective clinical study. The classes will combine didactic instruction with small group discussions and "hands on" learning. The emphasis of CI551 will be on early career advancement, competitivegrant writing, and literature evaluation. This course will focus on developing a fundable, career development award suitable for peer review. Evaluations will be through oral presentations and a completed career development application.
 

Leadership

Clinical Investigation Training Program (CITP) Leadership

Faculty and Mentors

CITP Faculty and Mentors

The Clinical Investigation Training Program’s faculty members are nationally-renowned scholars and researchers who are experts in teaching and conducting research. Our multidisciplinary faculty members hail from the world’s most prestigious universities and research institutions, and are the recipients of numerous awards and accolades.  City of Hope’s intimate and collegial environment allows faculty members to be effective mentors to program participants, leading them down the path to professional clinical researcher.
Education and Training
As one of only a select few National Cancer Institute-designated Comprehensive Cancer Centers in the country, City of Hope integrates all aspects of cancer research, treatment and education. We offer a range of programs serving students, post-doctoral trainees, health and medical professionals.

City of Hope’s Irell & Manella Graduate School of Biological Sciences equips students with the skills and strategies to transform the future of modern medicine.
City of Hope has a long-standing commitment to Continuing Medical Education (CME), sharing advances in cancer research and treatment with the health-care community through CME courses such as conferences, symposia and other on and off campus CME opportunities for medical professionals.
Local and national conferences, in-depth educational training and a certification program provide both current and aspiring health professionals opportunities to further their knowledge in their fields of interest.
 
 
City of Hope offers a range of programs and services, such as Graduate Medical Education & Clinical Training, that serve students, post-doctoral trainees, medical professionals and staff.
The goal of the Postdoctoral Training Office is to ensure the postdoctoral experience at City of Hope is rewarding and meaningful to all participants.
NEWS & UPDATES
  • Advanced age tops the list among breast cancer risk factor for women. Not far behind is family history and genetics. Two City of Hope researchers delving deep into these issues recently received important grants to advance their studies. Arti Hurria, M.D., director of the Cancer and Aging Research Program, and ...
  • City of Hope is extending the reach of its lifesaving mission well beyond U.S. borders. To that end, three distinguished City of Hope leaders visited China earlier this year to lay the foundation for the institution’s new International Medicine Program. The program is part of City of Hope’s strategi...
  • A hallmark of cancer is that it doesn’t always limit itself to a primary location. It spreads. Breast cancer and lung cancer in particular are prone to spread, or metastasize, to the brain. Often the brain metastasis isn’t discovered until years after the initial diagnosis, just when patients were beginning to ...
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  • Most women who are treated for breast cancer with a mastectomy do not choose to undergo reconstructive surgery. The reasons for this, according to a recent JAMA Surgery study, vary. Nearly half say they do not want any additional surgery, while nearly 34 percent say breast cancer reconstruction simply isn’t imp...
  • The leading risk factor for breast cancer is simply being a woman. The second top risk factor is getting older. Obviously, these two factors cannot be controlled, which is why all women should be aware of their risk and how to minimize those risks. Many risk factors can be mitigated, and simple changes can lead...
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  • Screening for breast cancer has dramatically increased the number of cancers found before they cause symptoms – catching the disease when it is most treatable and curable. Mammograms, however, are not infallible. It’s important to conduct self-exams, and know the signs and symptoms that should be checked by a h...
  • Rob Darakjian was diagnosed with acute lymphoblastic leukemia at just 19 years old. He began chemotherapy and was in and out of the hospital for four months. After his fourth round of treatment, he received a bone marrow transplantation from an anonymous donor. Today, he’s cancer free.   In his previ...
  • In a single day, former professional triathlete Lisa Birk learned she couldn’t have children and that she had breast cancer. “Where do you go from there?” she asks. For Birk, who swims three miles, runs 10 miles and cycles every day, the answer  ultimately was a decision to take control of her cancer care. Afte...
  • More and more people are surviving cancer, thanks to advanced cancer treatments and screening tools. Today there are nearly 14.5 million cancer survivors in the United States. But in up to 20 percent of cancer patients, the disease ultimately spreads to their brain. Each year, nearly 170,000 new cases of brain ...
  • Cancer cells are masters of survival. Despite excessive damage to their most basic workings and the constant vigilance of the body’s immune system, they manage to persevere. Much of this extraordinary ability to survive falls under the control of proteins bearing the name STAT, short for signal transducer and a...
  • One person receives the breast cancer diagnosis, but the cancer affects the entire family. Couples, in particular, can find the diagnosis and treatment challenging, especially if they have traditional male/female communication styles. “Though every individual is unique, men and women often respond differently d...
  • Here’s a statistic you’ll hear and read frequently over the next month: One in eight women born in the United States will develop breast cancer at some point in her lifetime. Although this statement is accurate, based on breast cancer incidence rates in 2013, it’s often misunderstood. Leslie Bernstein, Ph.D., d...