A National Cancer Institute-designated Comprehensive Cancer Center

Make an appointment: 800-826-HOPE
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Who We Are

City of Hope is dedicated to making a difference in the lives of people with cancer, diabetes and other serious illnesses. Our mission is to transform the future of health care by turning science into a practical benefit, hope into reality. We accomplish this by providing outstanding care, conducting innovative research and offering vital education programs focused on eliminating these diseases.
 
Founded in 1913, City of Hope is one of only 41 comprehensive cancer centers in the nation, as designated by the National Cancer Institute. Our role as leaders in patient care, basic and clinical research, and the translation of science into tangible benefit is widely acknowledged.
 
Our community includes research associates, scientists, doctors, nurses, allied health professionals, graduate students, fundraising specialists, marketing professionals, volunteers and an extensive support staff. We are united by our desire to find cures, save lives and transform the future of health. Every discovery we make and every new treatment we create gives people the chance to live longer, better and more fully.
 
City of Hope continues to be a pioneer of patient centered care and remains committed to its tradition of exceptional care for patients, families and communities. Each day, we live out our credo:
 
"There is no profit in curing the body, if, in the process, we destroy the soul."
 

The City of Hope Story

The City of Hope story began in 1913, when a group of volunteers, spurred by compassion to help those afflicted with tuberculosis, established the Jewish Consumptive Relief Association (JCRA) and raised money to start a free, nonsectarian tuberculosis sanatorium.
 
After several fundraisers, the JCRA put a down payment on 10 acres of sun-soaked land in Duarte, where they would establish the Los Angeles Sanatorium a year later. The original sanatorium consisted of two canvas cottages. So was launched a century-long journey that would place City of Hope at the forefront of the nation’s leading medical and research institutions. 
 
By the mid-1940s, thanks to the discovery of antibiotics, tuberculosis was on the decline in the U.S. However, City of Hope rose to the next medical challenge, tackling the catastrophic disease of cancer — and later on, diabetes and HIV/AIDS — while reaffirming its humanitarian vision that “health is a human right.”

In the spirit of that vision, Samuel H. Golter, one of City of Hope’s early leaders, coined the phrase, “There is no profit in curing the body if, in the process, we destroy the soul.” Those words became City of Hope’s credo.
 
Over the decades, research conducted at City of Hope has led to significant advances in modern medicine, including the development of the first synthetic human insulin, human growth hormone and the technology behind the widely used cancer-fighting drugs Herceptin, Rituxan and Avastin.
 
Today, City of Hope has been designated as a comprehensive cancer center, the highest recognition bestowed by the National Cancer Institute, and is a founding member of the National Comprehensive Cancer Network, with research and treatment protocols that advance care throughout the nation.
 
As we look toward the next 100 years, we continue our mission and commitment to transform the future of medicine. Our researchers, physicians, nurses, educators and staff have made hope a reality for countless patients and their loved ones.
 
And our work is just beginning.
 
Historical Milestones
 
1913
The Jewish Consumptive Relief Association was officially incorporated. 10 acres of land were purchased to establish the Los Angeles Sanatorium.

1914
The sanatorium officially opens its doors.  During its first year, it admitted 31 patients.
 
1928
The Jewish Ex-Patients Home, which helps discharged tuberculosis patients with health education, job training and ongoing emotional and spiritual support, merges with the Los Angeles Sanatorium in 1928.
 
1937
The International Ladies’ Garment Workers Union contributes $45,000 toward the construction of the 64-bed Morris Hillquit Memorial Hospital. The finished building is dedicated in 1938, the sanatorium’s 25th anniversary year.
 
1946
With tuberculosis on the wane, Executive Director Samuel L. Golter outlines a plan to transform the sanatorium into a national medical center focused on cancer and other major diseases.
 
1949
The name "City of Hope", used since 1916, is formally adopted, reflecting the institution's broader ambitions.

1952
City of Hope partners with University of California, Los Angeles to establish the Cancer Research Institute on the Duarte campus.

1955
The so-called “cobalt bomb,” a radiation therapy machine developed by City of Hope scientists, is put into operation. The cobalt bomb delivered radiation to malignancies deep within the human body.

1957
The focus on compassionate care reaches new heights with the opening of Hope Village, which provides on-site housing for patients and their families traveling from across the nation.

1965
Executive Director Ben Horowitz unveils a master plan that calls for enlarging patient care, research and medical education facilities. This included expanding research and treatment programs for cancer and other diseases.

1976
The Bone Marrow Transplantation program (BMT) accepts its first patients. The BMT program will grow to become one of the largest and most successful transplantation programs in the country.

1978
Recombinant DNA techniques pioneered by City of Hope scientists lead to the development of synthetic human insulin (Humulin).

1983
The first Beckman Research Institute, a name that would become synonymous with leading-edge research, is established at City of Hope.

1983
Scientists at City of Hope discover how to manufacture immune proteins known as antibodies. This breakthrough leads to humanized monoclonal antibodies — and a new generation of "smart" cancer drugs including Herceptin, Rituxan and Avastin.

1997
The first Food and Drug Administration-approved human trials of a gene therapy for HIV/AIDS begin. This line of research would lead, in 2011, to the first long-term persistence of anti-HIV genes in patients with AIDS-related lymphoma treated through gene therapy.

1998
The National Cancer Institute designates City of Hope as a Comprehensive Cancer Center.

2000
The Center for Biomedicine & Genetics opens, enabling City of Hope to create biologically based treatments for use in clinical trials. In 2012, a facility producing chemically based drugs would open. These centers, and a complementary third facility, quickly translate discoveries into treatments.

2001
The National Institutes of Health designates City of Hope as an Islet Cell Resource Center.

2003
City of Hope becomes one of the first U.S. medical centers to perform laparoscopic radical prostatectomies to treat prostate cancer.

2005
The Helford Clinical Research Hospital opens, replacing Hillquit Hospital. The Helford Hospital maximizes the human side of patient care and significantly increases City of Hope’s capacity for surgical procedures and programs such as the BMT.

2008
Scientists at City of Hope begin the first in-human clinical trials of RNA-based gene therapy for HIV-related illnesses.

2010
The City of Hope Medical Foundation is established.

2011
City of Hope reaches its milestone 10,000th bone marrow transplant, becoming one of the largest and most successful transplant programs of its kind in the world.

2013
City of Hope celebrates its 100th anniversary.
 

Culture/Values

Our Mission:
City of Hope is transforming the future of health. Every day we turn science into practical benefit. We turn hope into reality. We accomplish this through exquisite care, innovative research and vital education focused on eliminating cancer and diabetes.
 
Our Values:
COMPASSION
From day one, compassion has been woven into the heart and soul of our institution.
Compassion for our patients, their families, and our team members.
 
We show compassion not only through treatment, but also through our philanthropy and advocacy, through our humanistic approach to research and care and through our day-to-day relationships with every individual.
 
We demonstrate compassion for our peers and colleagues by showing empathy and treating each other with dignity and respect.
 
SERVICE WITH A SENSE OF URGENCY
We focus on turning great science into practical benefit as quickly as possible.
 
We tenaciously pursue new and better ways to improve the lives of people around the world. We are driven to provide new treatments for more people every day.
 
Our passion for serving others extends to our own people. We believe that providing opportunities to our own team members to engage and build community with colleagues helps them work more effectively.
 
INTEGRITY
We choose the right path, not the easy one.
 
We promote a “just culture” environment that requires each of us to do the right thing to ensure patient safety. We do what’s best for our patients and our community, every moment of every day.
 
Integrity guides us to passionately engage in our work, step up to every challenge and conduct our business with transparency. We hold ourselves accountable for following through with our commitments and doing the right thing.

INTELLECTUAL CURIOSITY
Our reputation for scientific excellence stems from our determination to aggressively pursue new lines of inquiry.
 
We are lifelong learners committed to making pioneering discoveries and moving them forward for the benefit of patients and the scientific community worldwide. Our curiosity has fueled our innovation, creating life-changing moments and lifesaving breakthroughs, like developing the first synthetic human insulin and numerous cancer-fighting drugs.
 
EXCELLENCE
Our commitment to advancing science while providing compassionate care has established us as the benchmark in fighting cancer, diabetes and other life-threatening diseases.
 
We strive for excellence in our processes and outcomes without compromising safety. We encourage every individual to use their best judgment, achieve synergies and make decisions that align with our mission, values and worldwide reputation for excellence.
 
COLLABORATION
We work as one team, united by a common purpose. We are a community of experts, combining the resources of cutting-edge scientific research, drug manufacturing, clinical care, graduate education, philanthropy and supportive care services.
 
Recognizing the value that bringing together diverse perspectives provides, we create an environment where new partnerships thrive, where barriers to freely sharing knowledge do not exist and where the right stakeholders are engaged from the beginning.
 

Our Next 100 Years

At City of Hope, our mission and commitment to transform the future of health is based on our past success at doing just that. Our researchers, physicians, nurses, educators and staff have made hope a reality for thousands of patients and families. And our work is just beginning.
 
As we look ahead, our strategic plan will provide the focus necessary to uniquely attack life-threatening diseases. We’ll retain our innovative nimbleness to quickly advance the most promising areas of research, while retaining our commitment to the exquisite care of our patients and families.
 
Events and collaborations like Concert for Hope, Walk for Hope and ThinkCure! will enable us to extend our mission to younger generations, ensuring an ongoing legacy of diverse and committed supporters ready to move us forward into our second century of Hope.
 

Diversity and Inclusion

At City of Hope, we strive to create an inclusive environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally.
 
Each day brings an opportunity to strengthen our work, leverage our unique perspectives and improve our patients' experiences by learning from others.
 
We invite you to learn more about our commitment to diversity and inclusion. Click here to download our brochure.

Who We Are

Who We Are

City of Hope is dedicated to making a difference in the lives of people with cancer, diabetes and other serious illnesses. Our mission is to transform the future of health care by turning science into a practical benefit, hope into reality. We accomplish this by providing outstanding care, conducting innovative research and offering vital education programs focused on eliminating these diseases.
 
Founded in 1913, City of Hope is one of only 41 comprehensive cancer centers in the nation, as designated by the National Cancer Institute. Our role as leaders in patient care, basic and clinical research, and the translation of science into tangible benefit is widely acknowledged.
 
Our community includes research associates, scientists, doctors, nurses, allied health professionals, graduate students, fundraising specialists, marketing professionals, volunteers and an extensive support staff. We are united by our desire to find cures, save lives and transform the future of health. Every discovery we make and every new treatment we create gives people the chance to live longer, better and more fully.
 
City of Hope continues to be a pioneer of patient centered care and remains committed to its tradition of exceptional care for patients, families and communities. Each day, we live out our credo:
 
"There is no profit in curing the body, if, in the process, we destroy the soul."
 

100 Year Legacy

The City of Hope Story

The City of Hope story began in 1913, when a group of volunteers, spurred by compassion to help those afflicted with tuberculosis, established the Jewish Consumptive Relief Association (JCRA) and raised money to start a free, nonsectarian tuberculosis sanatorium.
 
After several fundraisers, the JCRA put a down payment on 10 acres of sun-soaked land in Duarte, where they would establish the Los Angeles Sanatorium a year later. The original sanatorium consisted of two canvas cottages. So was launched a century-long journey that would place City of Hope at the forefront of the nation’s leading medical and research institutions. 
 
By the mid-1940s, thanks to the discovery of antibiotics, tuberculosis was on the decline in the U.S. However, City of Hope rose to the next medical challenge, tackling the catastrophic disease of cancer — and later on, diabetes and HIV/AIDS — while reaffirming its humanitarian vision that “health is a human right.”

In the spirit of that vision, Samuel H. Golter, one of City of Hope’s early leaders, coined the phrase, “There is no profit in curing the body if, in the process, we destroy the soul.” Those words became City of Hope’s credo.
 
Over the decades, research conducted at City of Hope has led to significant advances in modern medicine, including the development of the first synthetic human insulin, human growth hormone and the technology behind the widely used cancer-fighting drugs Herceptin, Rituxan and Avastin.
 
Today, City of Hope has been designated as a comprehensive cancer center, the highest recognition bestowed by the National Cancer Institute, and is a founding member of the National Comprehensive Cancer Network, with research and treatment protocols that advance care throughout the nation.
 
As we look toward the next 100 years, we continue our mission and commitment to transform the future of medicine. Our researchers, physicians, nurses, educators and staff have made hope a reality for countless patients and their loved ones.
 
And our work is just beginning.
 
Historical Milestones
 
1913
The Jewish Consumptive Relief Association was officially incorporated. 10 acres of land were purchased to establish the Los Angeles Sanatorium.

1914
The sanatorium officially opens its doors.  During its first year, it admitted 31 patients.
 
1928
The Jewish Ex-Patients Home, which helps discharged tuberculosis patients with health education, job training and ongoing emotional and spiritual support, merges with the Los Angeles Sanatorium in 1928.
 
1937
The International Ladies’ Garment Workers Union contributes $45,000 toward the construction of the 64-bed Morris Hillquit Memorial Hospital. The finished building is dedicated in 1938, the sanatorium’s 25th anniversary year.
 
1946
With tuberculosis on the wane, Executive Director Samuel L. Golter outlines a plan to transform the sanatorium into a national medical center focused on cancer and other major diseases.
 
1949
The name "City of Hope", used since 1916, is formally adopted, reflecting the institution's broader ambitions.

1952
City of Hope partners with University of California, Los Angeles to establish the Cancer Research Institute on the Duarte campus.

1955
The so-called “cobalt bomb,” a radiation therapy machine developed by City of Hope scientists, is put into operation. The cobalt bomb delivered radiation to malignancies deep within the human body.

1957
The focus on compassionate care reaches new heights with the opening of Hope Village, which provides on-site housing for patients and their families traveling from across the nation.

1965
Executive Director Ben Horowitz unveils a master plan that calls for enlarging patient care, research and medical education facilities. This included expanding research and treatment programs for cancer and other diseases.

1976
The Bone Marrow Transplantation program (BMT) accepts its first patients. The BMT program will grow to become one of the largest and most successful transplantation programs in the country.

1978
Recombinant DNA techniques pioneered by City of Hope scientists lead to the development of synthetic human insulin (Humulin).

1983
The first Beckman Research Institute, a name that would become synonymous with leading-edge research, is established at City of Hope.

1983
Scientists at City of Hope discover how to manufacture immune proteins known as antibodies. This breakthrough leads to humanized monoclonal antibodies — and a new generation of "smart" cancer drugs including Herceptin, Rituxan and Avastin.

1997
The first Food and Drug Administration-approved human trials of a gene therapy for HIV/AIDS begin. This line of research would lead, in 2011, to the first long-term persistence of anti-HIV genes in patients with AIDS-related lymphoma treated through gene therapy.

1998
The National Cancer Institute designates City of Hope as a Comprehensive Cancer Center.

2000
The Center for Biomedicine & Genetics opens, enabling City of Hope to create biologically based treatments for use in clinical trials. In 2012, a facility producing chemically based drugs would open. These centers, and a complementary third facility, quickly translate discoveries into treatments.

2001
The National Institutes of Health designates City of Hope as an Islet Cell Resource Center.

2003
City of Hope becomes one of the first U.S. medical centers to perform laparoscopic radical prostatectomies to treat prostate cancer.

2005
The Helford Clinical Research Hospital opens, replacing Hillquit Hospital. The Helford Hospital maximizes the human side of patient care and significantly increases City of Hope’s capacity for surgical procedures and programs such as the BMT.

2008
Scientists at City of Hope begin the first in-human clinical trials of RNA-based gene therapy for HIV-related illnesses.

2010
The City of Hope Medical Foundation is established.

2011
City of Hope reaches its milestone 10,000th bone marrow transplant, becoming one of the largest and most successful transplant programs of its kind in the world.

2013
City of Hope celebrates its 100th anniversary.
 

Culture/Values

Culture/Values

Our Mission:
City of Hope is transforming the future of health. Every day we turn science into practical benefit. We turn hope into reality. We accomplish this through exquisite care, innovative research and vital education focused on eliminating cancer and diabetes.
 
Our Values:
COMPASSION
From day one, compassion has been woven into the heart and soul of our institution.
Compassion for our patients, their families, and our team members.
 
We show compassion not only through treatment, but also through our philanthropy and advocacy, through our humanistic approach to research and care and through our day-to-day relationships with every individual.
 
We demonstrate compassion for our peers and colleagues by showing empathy and treating each other with dignity and respect.
 
SERVICE WITH A SENSE OF URGENCY
We focus on turning great science into practical benefit as quickly as possible.
 
We tenaciously pursue new and better ways to improve the lives of people around the world. We are driven to provide new treatments for more people every day.
 
Our passion for serving others extends to our own people. We believe that providing opportunities to our own team members to engage and build community with colleagues helps them work more effectively.
 
INTEGRITY
We choose the right path, not the easy one.
 
We promote a “just culture” environment that requires each of us to do the right thing to ensure patient safety. We do what’s best for our patients and our community, every moment of every day.
 
Integrity guides us to passionately engage in our work, step up to every challenge and conduct our business with transparency. We hold ourselves accountable for following through with our commitments and doing the right thing.

INTELLECTUAL CURIOSITY
Our reputation for scientific excellence stems from our determination to aggressively pursue new lines of inquiry.
 
We are lifelong learners committed to making pioneering discoveries and moving them forward for the benefit of patients and the scientific community worldwide. Our curiosity has fueled our innovation, creating life-changing moments and lifesaving breakthroughs, like developing the first synthetic human insulin and numerous cancer-fighting drugs.
 
EXCELLENCE
Our commitment to advancing science while providing compassionate care has established us as the benchmark in fighting cancer, diabetes and other life-threatening diseases.
 
We strive for excellence in our processes and outcomes without compromising safety. We encourage every individual to use their best judgment, achieve synergies and make decisions that align with our mission, values and worldwide reputation for excellence.
 
COLLABORATION
We work as one team, united by a common purpose. We are a community of experts, combining the resources of cutting-edge scientific research, drug manufacturing, clinical care, graduate education, philanthropy and supportive care services.
 
Recognizing the value that bringing together diverse perspectives provides, we create an environment where new partnerships thrive, where barriers to freely sharing knowledge do not exist and where the right stakeholders are engaged from the beginning.
 

Our Next 100 Years

Our Next 100 Years

At City of Hope, our mission and commitment to transform the future of health is based on our past success at doing just that. Our researchers, physicians, nurses, educators and staff have made hope a reality for thousands of patients and families. And our work is just beginning.
 
As we look ahead, our strategic plan will provide the focus necessary to uniquely attack life-threatening diseases. We’ll retain our innovative nimbleness to quickly advance the most promising areas of research, while retaining our commitment to the exquisite care of our patients and families.
 
Events and collaborations like Concert for Hope, Walk for Hope and ThinkCure! will enable us to extend our mission to younger generations, ensuring an ongoing legacy of diverse and committed supporters ready to move us forward into our second century of Hope.
 

Diversity and Inclusion

Diversity and Inclusion

At City of Hope, we strive to create an inclusive environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally.
 
Each day brings an opportunity to strengthen our work, leverage our unique perspectives and improve our patients' experiences by learning from others.
 
We invite you to learn more about our commitment to diversity and inclusion. Click here to download our brochure.
We're a community of people characterized by our diversity of thought, background and approach.
 
We have career opportunities in nursing, research, allied health, business support and many other areas.
 
City of Hope employees enjoy excellent benefits and an environment that inspires wellness.
 
In addition to our main campus in Duarte, CA, we have several locations throughout the Los Angeles vicinity.
 
Current employees and external candidates are invited to explore our career opportunities.
 
City of Hope is a community of people characterized by our diversity of thought, background, and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. Download our Diversity & Inclusion brochure.
Learn more about City of Hope's institutional distinctions, breakthrough innovations and collaborations.


NEWS & UPDATES
  • The outlook and length of survival has not changed much in the past 25 years for patients suffering from an aggressive form of pancreatic cancer known as pancreatic ductal adenocarcinoma (PDAC). These patients still have few options for therapy; currently available therapies are generally toxic and do not incre...
  • “With bladder cancer, the majority of patients that I see can be cured,” said urologist Kevin Chan, M.D., head of reconstructive urology at City of Hope. “The challenge is to get patients the same quality of life that they had before surgery.” To meet this challenge, Chan and the urologic team at City of Hope [...
  • Already pioneers in the use of immunotherapy, City of Hope researchers are now testing the bold approach to cancer treatment against one of medicine’s biggest challenges: brain cancer. This month, they will launch a clinical trial using patients’ own modified T cells to fight advanced brain tumors. One of but a...
  • Brain cancer may be one of the most-frightening diagnoses people can receive, striking at the very center of who we are as individuals. Further, it often develops over time, causing no symptoms until it’s already advanced. Listen to City of Hope Radio as Behnam Badie, M.D., director of the Brain Tumor Pro...
  • The whole is greater than the sum of its parts. It takes a village. No man is an island. Choose your aphorism: It’s a simple truth that collaboration usually is better than isolation. That’s especially true when you’re trying to introduce healthful habits and deliver health care to people at risk of disease and...
  • When Maryland Governor Larry Hogan announced earlier this week that he has the most common form of non-Hodgkin lymphoma, he was giving voice to the experience of more than 71,000 Americans each year. The announcement came with Hogan’s promise to stay in office while undergoing aggressive treatment for the...
  • The spine can be affected by many different kinds of tumors. Malignant, or cancerous, tumors can arise within the spine itself. Secondary spinal tumors, which are actually much more common, begin as cancers in another part of the body, such as the breast and prostate, and then spread, or metastasize, to the spi...
  • Although most cancer occurs in older adults, the bulk of cancer research doesn’t focus on this vulnerable and fast-growing population. City of Hope and its Cancer and Aging Research Team aim to change that, and they’re getting a significant boost from Professional Practice Leader Peggy Burhenn, R.N....
  • Liz Graef-Larcher’s first brain tumor was discovered by accident six years ago. The then-48-year-old with a long history of sinus problems and headaches had been sent for an MRI, and the scan found a lesion in her brain called a meningioma – a tumor that arises in the meninges, the layers of tissue that cover a...
  • The colon and rectum are parts of the body’s gastrointestinal system, also called the digestive tract. After food is digested in the stomach and nutrients are absorbed in the small intestine, the remaining material moves down into the lower large intestine (colon) where water and nutrients are absorbed. The low...
  • If there is one truism about hospital stays it is that patients want to get out. For many, however, the joy of being discharged is tempered by the unexpected challenges that recovery in a new setting may pose. Even with professional help, the quality of care and treatment that patients receive at City of Hope [...
  • Jana Portnow, M.D., associate director of the Brain Tumor Program at City of Hope, didn’t expect to specialize in treating brain tumors. But, early in her career, she undertook a year of research on pain management and palliative care and, in that program, got to know many patients with brain tumors. After that...
  • Ask any patient: Nurses are as pivotal in their care as doctors. They answer the call of a patient in the middle of the night, they hold the patient’s hand as he or she takes on yet another round of treatment and, in the best-case scenario, they wave goodbye as the patient leaves the hospital, […]
  • Many oncologists, not to mention their patients, might think that there’s no place for mathematical analysis in the treatment of cancer. They might think that all treatment decisions are based on unique factors affecting individual patients, with no connection to other patients and their treatment regimen...
  • Within three days in 2007, Stephanie Hosford, then 37, learned that she was pregnant with her long-awaited second child – and that she had triple-negative breast cancer. Soon afterward, Hosford discovered that she and her husband, Grant, had been approved to adopt a little girl from China.  After encountering m...