A National Cancer Institute-designated Comprehensive Cancer Center

Make an appointment: 800-826-HOPE
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Community Outreach

As a Comprehensive Cancer Center, City of Hope plays an important role in the community. We continually use the knowledge gained from our ongoing research to influence the standards of prevention and care, and to educate physicians, caregivers, and patients alike.
 
 

General Information About Cancer

What Is Cancer?
Cancer occurs when cells in the body divide and grow abnormally.
 
Normally, cells throughout the body divide and grow as children's bodies develop, and as adult bodies replace old or injured cells. During this methodical system, new cells form, grow, and stop growing at the appropriate time. When cancer occurs, cell growth becomes uncontrolled. Often, but not always, these cancer cells form into a solid mass called a tumor. Not all tumors are cancerous, however: cancerous tumors are called “malignant,” while non-cancerous tumors are known as “benign.” If the cancerous cells are blood cells, as in leukemia, there is no solid tumor. Early detection and treatment are very important to increasing the patient's chances of recovery.
 
Cancer can occur in many parts of the body, and can take many different forms. The various forms can behave very differently from one another--they may grow at differing rates, and respond to treatments inconsistently. Cancer can also spread to other parts of the body through the bloodstream or lymphatic system (this is called metastasis), but the original site of the cancerous cells determines the cancer type.
 
What Causes Cancer?
The unusual cell growth that brings about cancer is the result of damage to DNA -- the substance inside all cells that directs cell behavior. Damaged DNA can be caused by genetics, by behavior (such as smoking or diet), or by things in the environment (such as air pollutants, radiation or occupational exposure to certain chemicals). Usually, the body can repair damaged DNA, but cancer cells evade this natural process.
 
Treating Cancer
Cancer is traditionally treated using three types of therapy: surgery, radiation, and chemotherapy. Depending on the type of cancer and its stage (how far the cancer has progressed), your doctor may use one of these methods or a combination of them in order to achieve the best possible result.
 
Today, in addition to these three approaches, new and promising therapies for cancer are being developed and used. These new approaches include gene therapy and immunotherapy, and may offer new hope to those who have not benefited from conventional treatment methods.
 
The City of Hope Approach
City of Hope, one of just 41 NCI-designated Comprehensive Cancer Centers in the United States, is dedicated to the prevention, treatment and cure of many different types of cancer. City of Hope has a world-class staff of researchers and physicians who are constantly developing new approaches to treating cancer.Last year, City of Hope conducted more than 300 studies enrolling more than 5,000 patients.
 
In just one example of our leading-edge research, City of Hope is the first – and currently only – institution in the world to perform a clinical study using genetically-engineered T-cells to recognize and attack glioma, a highly lethal (and unfortunately, quite common) form of brain cancer. Learn more about our treatment approaches.
 
Cancer Prevention
Through painstaking effort and years of research, scientists have been able to identify many of the causes of cancer. Today, it is believed that about 75 percent of cancer cases are tied in some way to how we live our lives. Since our lifestyle does contribute to the risk of having cancer, prevention often depends on knowing as much as possible about our own risk factors. It’s important to remember that cancer prevention is an ongoing process.
 
  • Carefully identify lifestyle factors such as smoking, dietary habits, or occupational hazards that might contribute to your risk of developing cancer.
  • Think about which of these lifestyle risk factors you can control.
  • Begin to make simple changes in lifestyle that may help lower your cancer risk. These changes often involve choices that are made every day.
  • The American Cancer Society recommends a cancer-related checkup every three years for people between the ages of 20 to 39 and annually for people age 40 or older.

Additional Information and Resources
This website is designed to provide information about the advanced treatment services and leading biomedical research available at City of Hope.
 
For general information on all types of cancers, as well as cancer causes and prevention, the National Cancer Institute (www.cancer.gov) and American Cancer Society (www.cancer.org) are excellent sources.
 
Become a Patient
City of Hope is committed to making the process of becoming a patient here as easy as possible. Call 800-826-HOPE (4673) or complete the online appointment form.
 

Community Outreach

Community Outreach

As a Comprehensive Cancer Center, City of Hope plays an important role in the community. We continually use the knowledge gained from our ongoing research to influence the standards of prevention and care, and to educate physicians, caregivers, and patients alike.
 
 

General Information About Cancer

General Information About Cancer

What Is Cancer?
Cancer occurs when cells in the body divide and grow abnormally.
 
Normally, cells throughout the body divide and grow as children's bodies develop, and as adult bodies replace old or injured cells. During this methodical system, new cells form, grow, and stop growing at the appropriate time. When cancer occurs, cell growth becomes uncontrolled. Often, but not always, these cancer cells form into a solid mass called a tumor. Not all tumors are cancerous, however: cancerous tumors are called “malignant,” while non-cancerous tumors are known as “benign.” If the cancerous cells are blood cells, as in leukemia, there is no solid tumor. Early detection and treatment are very important to increasing the patient's chances of recovery.
 
Cancer can occur in many parts of the body, and can take many different forms. The various forms can behave very differently from one another--they may grow at differing rates, and respond to treatments inconsistently. Cancer can also spread to other parts of the body through the bloodstream or lymphatic system (this is called metastasis), but the original site of the cancerous cells determines the cancer type.
 
What Causes Cancer?
The unusual cell growth that brings about cancer is the result of damage to DNA -- the substance inside all cells that directs cell behavior. Damaged DNA can be caused by genetics, by behavior (such as smoking or diet), or by things in the environment (such as air pollutants, radiation or occupational exposure to certain chemicals). Usually, the body can repair damaged DNA, but cancer cells evade this natural process.
 
Treating Cancer
Cancer is traditionally treated using three types of therapy: surgery, radiation, and chemotherapy. Depending on the type of cancer and its stage (how far the cancer has progressed), your doctor may use one of these methods or a combination of them in order to achieve the best possible result.
 
Today, in addition to these three approaches, new and promising therapies for cancer are being developed and used. These new approaches include gene therapy and immunotherapy, and may offer new hope to those who have not benefited from conventional treatment methods.
 
The City of Hope Approach
City of Hope, one of just 41 NCI-designated Comprehensive Cancer Centers in the United States, is dedicated to the prevention, treatment and cure of many different types of cancer. City of Hope has a world-class staff of researchers and physicians who are constantly developing new approaches to treating cancer.Last year, City of Hope conducted more than 300 studies enrolling more than 5,000 patients.
 
In just one example of our leading-edge research, City of Hope is the first – and currently only – institution in the world to perform a clinical study using genetically-engineered T-cells to recognize and attack glioma, a highly lethal (and unfortunately, quite common) form of brain cancer. Learn more about our treatment approaches.
 
Cancer Prevention
Through painstaking effort and years of research, scientists have been able to identify many of the causes of cancer. Today, it is believed that about 75 percent of cancer cases are tied in some way to how we live our lives. Since our lifestyle does contribute to the risk of having cancer, prevention often depends on knowing as much as possible about our own risk factors. It’s important to remember that cancer prevention is an ongoing process.
 
  • Carefully identify lifestyle factors such as smoking, dietary habits, or occupational hazards that might contribute to your risk of developing cancer.
  • Think about which of these lifestyle risk factors you can control.
  • Begin to make simple changes in lifestyle that may help lower your cancer risk. These changes often involve choices that are made every day.
  • The American Cancer Society recommends a cancer-related checkup every three years for people between the ages of 20 to 39 and annually for people age 40 or older.

Additional Information and Resources
This website is designed to provide information about the advanced treatment services and leading biomedical research available at City of Hope.
 
For general information on all types of cancers, as well as cancer causes and prevention, the National Cancer Institute (www.cancer.gov) and American Cancer Society (www.cancer.org) are excellent sources.
 
Become a Patient
City of Hope is committed to making the process of becoming a patient here as easy as possible. Call 800-826-HOPE (4673) or complete the online appointment form.
 
Cancer Information
Find out more about cancer and how it develops, including risk factors, early detection, diagnosis, prevention and treatment. You can also find additional resources, statistics and a glossary from the National Cancer Institute and the American Cancer Society that may help in your search for more information about cancer.
Discover the wide range of progressive cancer treatment options at City of Hope designed to meet the individual needs of each patient. Here, medical research and clinical care are integrated, speeding the application of scientific discoveries toward better, more effective patient cancer treatments.
Only a National Cancer Institute (NCI)-designated Comprehensive Cancer Center such as City of Hope offers a full complement of services designed to address all aspects of cancer, from understanding its origins to developing new therapies.
NCICCC
Community Outreach
As a Comprehensive Cancer Center, City of Hope plays an important role in the community. We continually use the knowledge gained from our ongoing research to influence the standards of prevention and care, and to educate physicians, caregivers, and patients alike.
 
    CCARE - Center of Community Alliance for Research and Education

    Sitio web de City of Hope en español - City of Hope Spanish-language website
 


NEWS & UPDATES
  • Joselyn Miller received a lifesaving bone marrow transplant at City of Hope two years ago. Here, she reflects on her gratitude as a bone marrow recipient and on giving back. By Joselyn Miller thank•ful adjective  \ˈthaŋk-fəl\ :  conscious of benefit received :  glad that something has happened or not happened, ...
  • When it comes to cancer, your family history may provide more questions than answers: How do my genes increase my risk for cancer? No one in my family has had cancer; does that mean I won’t get cancer? What cancers are common in certain populations and ethnicities? City of Hope experts have some guidance. “Your...
  • The body’s immune system is usually adept at attacking outside invaders such as bacteria and viruses. But because cancer originates from the body’s own cells, the immune system can fail to see it as foreign. As a result, the body’s most powerful ally can remain largely idle against cancer as the disease progres...
  • On Jan. 1, 2015, five City of Hope patients who have journeyed through cancer will welcome the new year with their loved ones atop City of Hope’s Tournament of Roses Parade float. The theme of the float is “Made Possible by HOPE.” The theme of the parade is “Inspiring Stories.” Her...
  • Are you thinking about switching from traditional cigarettes to e-cigarettes for the Great American Smokeout? Are you thinking that might be a better option than the traditional quit-smoking route? Think again. For lung expert Brian Tiep, M.D., the dislike and distrust he feels for e-cigs comes down to this: Th...
  • Hematologist Robert Chen, M.D., is boosting scientific discovery at City of Hope and, by extension, across the nation. Just ask the National Cancer Institute. The institution recently awarded Chen the much-sought-after Clinical Investigator Team Leadership Award for boosting scientific discovery at City of Hope...
  • Great strides have been made in treating cancer – including lung cancer – but by the time people show symptoms of the disease, the cancer has usually advanced. That’s because, at early stages, lung cancer has no symptoms. Only recently has lung cancer screening become an option. (Read more about the risks...
  • Identifying cures for currently incurable diseases and providing patients with safe, fast and potentially lifesaving treatments is the focus of City of Hope’s new Alpha Clinic for Cell Therapy and Innovation (ACT-I). The clinic is funded by an $8 million, five-year grant from the California Institute for Regene...
  • Cancer is a couple’s disease. It affects not just the person diagnosed, but his or her partner as well. It also affects the ability of both people to communicate effectively. The Couples Coping with Cancer Together program at City of Hope teaches couples how to communicate and solve problems as a unit. He...
  • Chemotherapy drugs work by either killing cancer cells or by stopping them from multiplying, that is, dividing. Some of the more powerful drugs used to treat cancer do their job by interfering with the cancer cells’ DNA and RNA growth, preventing them from copying themselves and dividing. Such drugs, however, l...
  • During October, everything seems to turn pink – clothing, the NFL logo, tape dispensers, boxing gloves, blenders, soup cans, you name it – in order to raise awareness for what many believe is the most dangerous cancer that affects women: breast cancer. But, in addition to thinking pink, women should...
  • In February 2003, when she was only 16 months old, Maya Gallardo was diagnosed with acute myelogenous leukemia (AML) and, to make matters much worse, pneumonia. The pneumonia complicated what was already destined to be grueling treatment regimen. To assess the extent of her illness, Maya had to endure a spinal ...
  • Former smokers age 55 to 74 who rely on Medicare for health care services have just received a long-hoped-for announcement. Under a proposed decision from the Centers for Medicare and Medicaid Services, they’ll now have access to lung cancer screening with a low-dose CT scan. The proposed decision, announ...
  • City of Hope has a longstanding commitment to combating diabetes, a leading national and global health threat. Already, it’s scored some successes, from research that led to the development of synthetic human insulin – still used by millions of patients – to potentially lifesaving islet cell transplants. Diabet...
  • Dee Hunt never smoked. Neither did her five sisters and brothers. They didn’t have exposure to radon or asbestos, either. That didn’t prevent every one of them from being diagnosed with lung cancer. Their parents were smokers, but they’d all left home more than 30 years before any of them were diagn...