A National Cancer Institute-designated Comprehensive Cancer Center

Make an appointment: 800-826-HOPE
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Community Outreach

As a Comprehensive Cancer Center, City of Hope plays an important role in the community. We continually use the knowledge gained from our ongoing research to influence the standards of prevention and care, and to educate physicians, caregivers, and patients alike.
 
 

General Information About Cancer

What Is Cancer?
Cancer occurs when cells in the body divide and grow abnormally.
 
Normally, cells throughout the body divide and grow as children's bodies develop, and as adult bodies replace old or injured cells. During this methodical system, new cells form, grow, and stop growing at the appropriate time. When cancer occurs, cell growth becomes uncontrolled. Often, but not always, these cancer cells form into a solid mass called a tumor. Not all tumors are cancerous, however: cancerous tumors are called “malignant,” while non-cancerous tumors are known as “benign.” If the cancerous cells are blood cells, as in leukemia, there is no solid tumor. Early detection and treatment are very important to increasing the patient's chances of recovery.
 
Cancer can occur in many parts of the body, and can take many different forms. The various forms can behave very differently from one another--they may grow at differing rates, and respond to treatments inconsistently. Cancer can also spread to other parts of the body through the bloodstream or lymphatic system (this is called metastasis), but the original site of the cancerous cells determines the cancer type.
 
What Causes Cancer?
The unusual cell growth that brings about cancer is the result of damage to DNA -- the substance inside all cells that directs cell behavior. Damaged DNA can be caused by genetics, by behavior (such as smoking or diet), or by things in the environment (such as air pollutants, radiation or occupational exposure to certain chemicals). Usually, the body can repair damaged DNA, but cancer cells evade this natural process.
 
Treating Cancer
Cancer is traditionally treated using three types of therapy: surgery, radiation, and chemotherapy. Depending on the type of cancer and its stage (how far the cancer has progressed), your doctor may use one of these methods or a combination of them in order to achieve the best possible result.
 
Today, in addition to these three approaches, new and promising therapies for cancer are being developed and used. These new approaches include gene therapy and immunotherapy, and may offer new hope to those who have not benefited from conventional treatment methods.
 
The City of Hope Approach
City of Hope, one of just 41 NCI-designated Comprehensive Cancer Centers in the United States, is dedicated to the prevention, treatment and cure of many different types of cancer. City of Hope has a world-class staff of researchers and physicians who are constantly developing new approaches to treating cancer.Last year, City of Hope conducted more than 300 studies enrolling more than 5,000 patients.
 
In just one example of our leading-edge research, City of Hope is the first – and currently only – institution in the world to perform a clinical study using genetically-engineered T-cells to recognize and attack glioma, a highly lethal (and unfortunately, quite common) form of brain cancer. Learn more about our treatment approaches.
 
Cancer Prevention
Through painstaking effort and years of research, scientists have been able to identify many of the causes of cancer. Today, it is believed that about 75 percent of cancer cases are tied in some way to how we live our lives. Since our lifestyle does contribute to the risk of having cancer, prevention often depends on knowing as much as possible about our own risk factors. It’s important to remember that cancer prevention is an ongoing process.
 
  • Carefully identify lifestyle factors such as smoking, dietary habits, or occupational hazards that might contribute to your risk of developing cancer.
  • Think about which of these lifestyle risk factors you can control.
  • Begin to make simple changes in lifestyle that may help lower your cancer risk. These changes often involve choices that are made every day.
  • The American Cancer Society recommends a cancer-related checkup every three years for people between the ages of 20 to 39 and annually for people age 40 or older.

Additional Information and Resources
This website is designed to provide information about the advanced treatment services and leading biomedical research available at City of Hope.
 
For general information on all types of cancers, as well as cancer causes and prevention, the National Cancer Institute (www.cancer.gov) and American Cancer Society (www.cancer.org) are excellent sources.
 
Become a Patient
City of Hope is committed to making the process of becoming a patient here as easy as possible. Call 800-826-HOPE (4673) or complete the online appointment form.
 

Community Outreach

Community Outreach

As a Comprehensive Cancer Center, City of Hope plays an important role in the community. We continually use the knowledge gained from our ongoing research to influence the standards of prevention and care, and to educate physicians, caregivers, and patients alike.
 
 

General Information About Cancer

General Information About Cancer

What Is Cancer?
Cancer occurs when cells in the body divide and grow abnormally.
 
Normally, cells throughout the body divide and grow as children's bodies develop, and as adult bodies replace old or injured cells. During this methodical system, new cells form, grow, and stop growing at the appropriate time. When cancer occurs, cell growth becomes uncontrolled. Often, but not always, these cancer cells form into a solid mass called a tumor. Not all tumors are cancerous, however: cancerous tumors are called “malignant,” while non-cancerous tumors are known as “benign.” If the cancerous cells are blood cells, as in leukemia, there is no solid tumor. Early detection and treatment are very important to increasing the patient's chances of recovery.
 
Cancer can occur in many parts of the body, and can take many different forms. The various forms can behave very differently from one another--they may grow at differing rates, and respond to treatments inconsistently. Cancer can also spread to other parts of the body through the bloodstream or lymphatic system (this is called metastasis), but the original site of the cancerous cells determines the cancer type.
 
What Causes Cancer?
The unusual cell growth that brings about cancer is the result of damage to DNA -- the substance inside all cells that directs cell behavior. Damaged DNA can be caused by genetics, by behavior (such as smoking or diet), or by things in the environment (such as air pollutants, radiation or occupational exposure to certain chemicals). Usually, the body can repair damaged DNA, but cancer cells evade this natural process.
 
Treating Cancer
Cancer is traditionally treated using three types of therapy: surgery, radiation, and chemotherapy. Depending on the type of cancer and its stage (how far the cancer has progressed), your doctor may use one of these methods or a combination of them in order to achieve the best possible result.
 
Today, in addition to these three approaches, new and promising therapies for cancer are being developed and used. These new approaches include gene therapy and immunotherapy, and may offer new hope to those who have not benefited from conventional treatment methods.
 
The City of Hope Approach
City of Hope, one of just 41 NCI-designated Comprehensive Cancer Centers in the United States, is dedicated to the prevention, treatment and cure of many different types of cancer. City of Hope has a world-class staff of researchers and physicians who are constantly developing new approaches to treating cancer.Last year, City of Hope conducted more than 300 studies enrolling more than 5,000 patients.
 
In just one example of our leading-edge research, City of Hope is the first – and currently only – institution in the world to perform a clinical study using genetically-engineered T-cells to recognize and attack glioma, a highly lethal (and unfortunately, quite common) form of brain cancer. Learn more about our treatment approaches.
 
Cancer Prevention
Through painstaking effort and years of research, scientists have been able to identify many of the causes of cancer. Today, it is believed that about 75 percent of cancer cases are tied in some way to how we live our lives. Since our lifestyle does contribute to the risk of having cancer, prevention often depends on knowing as much as possible about our own risk factors. It’s important to remember that cancer prevention is an ongoing process.
 
  • Carefully identify lifestyle factors such as smoking, dietary habits, or occupational hazards that might contribute to your risk of developing cancer.
  • Think about which of these lifestyle risk factors you can control.
  • Begin to make simple changes in lifestyle that may help lower your cancer risk. These changes often involve choices that are made every day.
  • The American Cancer Society recommends a cancer-related checkup every three years for people between the ages of 20 to 39 and annually for people age 40 or older.

Additional Information and Resources
This website is designed to provide information about the advanced treatment services and leading biomedical research available at City of Hope.
 
For general information on all types of cancers, as well as cancer causes and prevention, the National Cancer Institute (www.cancer.gov) and American Cancer Society (www.cancer.org) are excellent sources.
 
Become a Patient
City of Hope is committed to making the process of becoming a patient here as easy as possible. Call 800-826-HOPE (4673) or complete the online appointment form.
 
Cancer Information
Find out more about cancer and how it develops, including risk factors, early detection, diagnosis, prevention and treatment. You can also find additional resources, statistics and a glossary from the National Cancer Institute and the American Cancer Society that may help in your search for more information about cancer.
Discover the wide range of progressive cancer treatment options at City of Hope designed to meet the individual needs of each patient. Here, medical research and clinical care are integrated, speeding the application of scientific discoveries toward better, more effective patient cancer treatments.
Only a National Cancer Institute (NCI)-designated Comprehensive Cancer Center such as City of Hope offers a full complement of services designed to address all aspects of cancer, from understanding its origins to developing new therapies.
NCICCC
Community Outreach
As a Comprehensive Cancer Center, City of Hope plays an important role in the community. We continually use the knowledge gained from our ongoing research to influence the standards of prevention and care, and to educate physicians, caregivers, and patients alike.
 
    CCARE - Center of Community Alliance for Research and Education

    Sitio web de City of Hope en español - City of Hope Spanish-language website
 


NEWS & UPDATES
  • Surgery for head and neck cancers is unarguably complex, requiring extremely controlled movements and exceptional training. “Given where we are operating, our primary concern is maintaining speaking, swallowing and breathing,” said Ellie Maghami, M.D., chief of head and neck surgery, who recently teamed with Ro...
  • Henry Ford said it well: “Working together is success.” For biomedical researchers, this is especially true. The challenges they face often require expertise from multiple fields to find answers and solutions. Scientists seeking cures for type 1 diabetes in particular must overcome biological, medical and techn...
  • Superheroes are making plenty of headlines as the summer blockbuster season opens. At City of Hope, a 9-year-old girl wept as she hugged her own superhero: someone who had the superpower of healing her cancer. He didn’t wear flashy armor or a cape, but rather a plaid shirt. He doesn’t have a secret ...
  • Known for his ability to bring together, and lead, effective research teams, world-renowned translational research scientist and physician Larry W. Kwak, M.D., Ph.D., has joined City of Hope in a key leadership role within the institution’s new Hematologic Malignancies and Stem Cell Transplantation Instit...
  • To detect melanoma, the most deadly form of skin cancer, at its earliest, most treatable stage, conduct a head-to-toe skin self-examination once a month to check for suspicious moles.   Unusual, or atypical, moles can ultimately develop into skin cancer. Here is the ABCDE guide to potentially cancerous mol...
  • “Superheroes,” “grateful” and “lifesavers”: All are words patients have used to describe their bone marrow donors. For donors, “a great feeling” and “the right thing to do” seems to sum up their view of donating the stem cells used to save someone’s life. Bone marrow transplants of...
  • Updated: May 1, 2015 More than a decade after joining the bone marrow registry during a blood drive at the United States Military Academy at West Point, Phil Ratcliff received a call that he was a match for a leukemia patient. By then, he’d left his military career to start his own financial business, married [...
  • Updated: May 1. For Lars Nijland, the reason to become a member of a bone marrow registry was simple. “I always thought there would be no easier way to save somebody’s life,” said the 24-year-old student at Germany’s University of Goettingen, who signed up for the registry during a drive on his campus. Ni...
  • Updated: May 1 No parent ever wants to see their child hurting or sick in any way. Joanne Cooper’s daughter Amanda wasn’t sick, though. She seemed healthy. Vibrant. A straight-A student whose only major health ailment had been bouts of stress-related nausea. Then a blood test revealed that Amanda – now 9 years ...
  • Noe Chavez became animated when he recalled the story: “We were running a health event, screening folks for diabetes,” said the enthusiastic City of Hope population health researcher, “and this man comes over and starts talking to us about the trouble he’s having with his eyes. I spoke with him, listened ...
  • When Keith McKinny, 29, was first diagnosed with lymphoma and leukemia in 2010, the first person he thought of was former boyfriend Jason Mullins. The two hadn’t been in contact with each other for some time, but McKinny couldn’t think of anyone else with whom he wanted to be during that difficult period....
  • Updated: May 1 Yesenia Portillo’s search for a bone marrow donor started close to home. Her brother, sister and seven cousins all underwent testing, but none of them were a close enough match to donate the bone marrow stem cells she desperately needed for her transplant. Yesenia, now almost 16, had always been ...
  • Some of City of Hope’s most high-impact achievements have arisen from City of Hope’s globally recognized bone marrow transplant (BMT) program. The annual Karl G. Blume – Gerhard Schmidt Memorial Lecture in Transplantation Biology & Medicine — commemorating two of the most influential and revered...
  • Guido Marcucci, M.D., wants to put himself out of business. A respected clinician and esteemed basic and translational scientist, Marcucci joins City of Hope as co-director of the Gehr Family Center for Leukemia Research within the Hematologic Malignancies and Stem Cell Transplantation Institute. In this positi...
  • To say that myelofibrosis patients need more treatment options would be an understatement. The severely low platelet counts, known as thrombocytopenia, that are one of the hallmark symptoms of the disease can lead to chronic fatigue and weakness that not only damage quality of life but, ultimately, shorten life...