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Cancer and Aging Research Program

The number of older patients with cancer and surviving cancer is rapidly growing because the U.S. population is aging with a projected doubling in the number of patients 65 and older by 2030. Although the majority of cancers occur in older adults, these patients have been under-represented in national cancer clinical trials, which set the standards for oncology care. Few studies have specifically focused on the unique issues which face older adults such as the impact of age related declines in physiology, polypharmacy or comorbid medical conditions on treatment tolerance.
 
Arti Hurria, M.D. leads City of Hope's Cancer and Aging Research Program, the mission of which is to join investigators from all cancer disciplines to study biology, treatment and survivorship issues that face older adults with cancer. The results of this research will be applicable to the majority of patients with cancer because approximately 60 percent of cancer diagnoses and 70 percent of cancer mortality occur in patients over the age of 65.
 
 

Science to Meet a Critical Need

City of Hope is home to one of the few specialized research programs designed to meet the unique needs of older adults with cancer. This is a crucial area of study that will only grow in the coming years.
  • Between 2010 and 2030, cancer incidence is expected to rise 67 percent in those age 65 or older, compared to 11 percent for those under age 65.
  • Approximately 60 percent of all cancers occur in people aged 65 years or older.
  • Older adults with cancer are underrepresented in the clinical trials that shape national standards for cancer care.
 

Older Adults are Unique

Not all 70-year-olds are alike. Chronological age does not tell the whole story. The team of Arti Hurria, M.D., has developed a comprehensive assessment to determine the functional age of older adults, therefore enabling a more tailored approach to cancer care.
  • Utilizing the information gathered during the assessment, a score can be determined to predict which older adults will be at increased risk for chemotherapy side effects. Knowing which patients may suffer an increased risk of side effects could influence treatment decisions made by doctors and patients.
  • Older adults typically have other medical conditions that need to be considered when choosing the type of therapy.
  • Older adults often take several prescribed medications. A careful medication review needs to be performed in order to understand which can interact with cancer treatment.
  • Older adults may have different preferences regarding treatments, taking into account the side effects of various treatment options and the impact of therapy on their ability to live independently.
Older Adults

Clinical Trials

City of Hope's aggressive pursuit to discover better ways to help patients now – not years from now – places us among the leaders worldwide in the administration of clinical trials. Find out more about City of Hope's Clinical Trials.
 
Cancer and Aging Research Program's Clinical Trials
 

About Dr. Arti Hurria

 
 
 
Arti Hurria, M.D.
Arti Hurria, M.D.
Associate Professor of Medical Oncology
Director, Cancer and Aging
Research Program

Dr. Arti Hurria is a geriatrician and oncologist. She completed a geriatric fellowship in the Harvard Geriatric Fellowship Program, followed by a hematology-oncology fellowship at Memorial Sloan-Kettering Cancer Center. Dr. Hurria is the Director of the Cancer and Aging Research Program at City of Hope. The overall goal of Dr. Hurria’s research program is to improve the care of older adults with cancer. She is PI on a U13 grant in collaboration with the NIA and NCI to identify and develop research methodology that will lead to evidence-based recommendations to improve clinical care for older adults with cancer. She also serves as national PI on an R01 funded grant evaluating clinical and biological predictors of chemotherapy toxicity in older adults with breast cancer. These grants are executed in collaboration with members from the Cancer and Aging Research Group, which Dr. Hurria founded and leads. Additionally, Dr. Hurria is multi-PI on a R01 funded study evaluating the cognitive function of long-term survivors of breast cancer and PI on a U13 grant which will focus on incorporating aging research across specialties and providing a forum to support the expanded pool of physician-scientists focused in aging research. Dr. Hurria is Chair of the National Comprehensive Cancer Network Senior Adult Oncology Panel, Past President for the International Society of Geriatric Oncology, co-Vice Chair of the Alliance Cancer in the Elderly Committee, and Editor-in-Chief of the Journal of Geriatric Oncology. She is a recipient of the Paul Beeson Career Development Award in Aging Research and the American Society of Clinical Oncology-Association of Specialty Professors-Junior Development Award in Geriatric Oncology. In 2013, she received the ASCO B.J. Kennedy Award for Scientific Excellence in Geriatric Oncology. Her CV can be found here.
 

Cancer and Aging Research Program

Collaboration

Arti Hurria, M.D., founded and leads the Cancer and Aging Research Group, which joins investigators across the nation in collaborative research to design and implement clinical trials to improve the care of older adults with cancer. More information can be found at www.mycarg.org

How You Can Help

Donate today to provide hope for older adults with cancer through innovative research.

Research is the only way forward against cancer in older adults. And progress is only possible with the help of generous donors.

Your gift makes a difference. Join forces with Arti Hurria, M.D., and her team and help transform the future of health for older adults with cancer.

You can also create a personal fundraising page. Share your story and inspire friends, family and associates to support this lifesaving mission. Please visit https://ourhope.cityofhope.org/events/dr-hurria-fundraising-page/e43974.

To learn more, contact Janet Morgan, Senior Development Officer at jmorgan@coh.org.

City of Hope Philanthropy
1500 East Duarte Road, Duarte, CA 91010
800-667-5310
philanthropy@coh.org
 

Cancer and Aging Research Program

Cancer and Aging Research Program

The number of older patients with cancer and surviving cancer is rapidly growing because the U.S. population is aging with a projected doubling in the number of patients 65 and older by 2030. Although the majority of cancers occur in older adults, these patients have been under-represented in national cancer clinical trials, which set the standards for oncology care. Few studies have specifically focused on the unique issues which face older adults such as the impact of age related declines in physiology, polypharmacy or comorbid medical conditions on treatment tolerance.
 
Arti Hurria, M.D. leads City of Hope's Cancer and Aging Research Program, the mission of which is to join investigators from all cancer disciplines to study biology, treatment and survivorship issues that face older adults with cancer. The results of this research will be applicable to the majority of patients with cancer because approximately 60 percent of cancer diagnoses and 70 percent of cancer mortality occur in patients over the age of 65.
 
 

Science to Meet a Critical Need

City of Hope is home to one of the few specialized research programs designed to meet the unique needs of older adults with cancer. This is a crucial area of study that will only grow in the coming years.
  • Between 2010 and 2030, cancer incidence is expected to rise 67 percent in those age 65 or older, compared to 11 percent for those under age 65.
  • Approximately 60 percent of all cancers occur in people aged 65 years or older.
  • Older adults with cancer are underrepresented in the clinical trials that shape national standards for cancer care.
 

Older Adults are Unique

Not all 70-year-olds are alike. Chronological age does not tell the whole story. The team of Arti Hurria, M.D., has developed a comprehensive assessment to determine the functional age of older adults, therefore enabling a more tailored approach to cancer care.
  • Utilizing the information gathered during the assessment, a score can be determined to predict which older adults will be at increased risk for chemotherapy side effects. Knowing which patients may suffer an increased risk of side effects could influence treatment decisions made by doctors and patients.
  • Older adults typically have other medical conditions that need to be considered when choosing the type of therapy.
  • Older adults often take several prescribed medications. A careful medication review needs to be performed in order to understand which can interact with cancer treatment.
  • Older adults may have different preferences regarding treatments, taking into account the side effects of various treatment options and the impact of therapy on their ability to live independently.
Older Adults

Clinical Trials

City of Hope's aggressive pursuit to discover better ways to help patients now – not years from now – places us among the leaders worldwide in the administration of clinical trials. Find out more about City of Hope's Clinical Trials.
 
Cancer and Aging Research Program's Clinical Trials
 

About Dr. Arti Hurria

About Dr. Arti Hurria

 
 
 
Arti Hurria, M.D.
Arti Hurria, M.D.
Associate Professor of Medical Oncology
Director, Cancer and Aging
Research Program

Dr. Arti Hurria is a geriatrician and oncologist. She completed a geriatric fellowship in the Harvard Geriatric Fellowship Program, followed by a hematology-oncology fellowship at Memorial Sloan-Kettering Cancer Center. Dr. Hurria is the Director of the Cancer and Aging Research Program at City of Hope. The overall goal of Dr. Hurria’s research program is to improve the care of older adults with cancer. She is PI on a U13 grant in collaboration with the NIA and NCI to identify and develop research methodology that will lead to evidence-based recommendations to improve clinical care for older adults with cancer. She also serves as national PI on an R01 funded grant evaluating clinical and biological predictors of chemotherapy toxicity in older adults with breast cancer. These grants are executed in collaboration with members from the Cancer and Aging Research Group, which Dr. Hurria founded and leads. Additionally, Dr. Hurria is multi-PI on a R01 funded study evaluating the cognitive function of long-term survivors of breast cancer and PI on a U13 grant which will focus on incorporating aging research across specialties and providing a forum to support the expanded pool of physician-scientists focused in aging research. Dr. Hurria is Chair of the National Comprehensive Cancer Network Senior Adult Oncology Panel, Past President for the International Society of Geriatric Oncology, co-Vice Chair of the Alliance Cancer in the Elderly Committee, and Editor-in-Chief of the Journal of Geriatric Oncology. She is a recipient of the Paul Beeson Career Development Award in Aging Research and the American Society of Clinical Oncology-Association of Specialty Professors-Junior Development Award in Geriatric Oncology. In 2013, she received the ASCO B.J. Kennedy Award for Scientific Excellence in Geriatric Oncology. Her CV can be found here.
 

Team Members

Cancer and Aging Research Program

Collaboration

Collaboration

Arti Hurria, M.D., founded and leads the Cancer and Aging Research Group, which joins investigators across the nation in collaborative research to design and implement clinical trials to improve the care of older adults with cancer. More information can be found at www.mycarg.org

How You Can Help

How You Can Help

Donate today to provide hope for older adults with cancer through innovative research.

Research is the only way forward against cancer in older adults. And progress is only possible with the help of generous donors.

Your gift makes a difference. Join forces with Arti Hurria, M.D., and her team and help transform the future of health for older adults with cancer.

You can also create a personal fundraising page. Share your story and inspire friends, family and associates to support this lifesaving mission. Please visit https://ourhope.cityofhope.org/events/dr-hurria-fundraising-page/e43974.

To learn more, contact Janet Morgan, Senior Development Officer at jmorgan@coh.org.

City of Hope Philanthropy
1500 East Duarte Road, Duarte, CA 91010
800-667-5310
philanthropy@coh.org
 


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