A National Cancer Institute-designated Comprehensive Cancer Center

Make an appointment: 800-826-HOPE
Our Approach Bookmark and Share

Our Approach - Brain Tumors

As a patient at City of Hope, you have a highly experienced and dedicated team to treat your brain tumor. Whether you have a benign pituitary tumor or an aggressive glioblastoma, we offer a comprehensive, individualized approach to treating brain tumors.
 
Our Brain Tumor Team, including surgeons, medical oncologists and radiation oncologists, creates treatment plans tailored to each patient. Where possible, our surgeons use minimally invasive surgical techniques that minimize injury to the brain and surrounding structure. And our radiation oncologists use state-of-the-art radiation therapy techniques, including Helical TomoTherapy and stereotactic radiosurgery (SRS), which deliver highly localized doses of radiation to primary tumors and metastases while sparing as much normal tissue as possible. 
 
City of Hope researchers are conducting clinical trials of innovative therapies to find more effective treatments for patients with brain tumors. We believe the future of neurosurgery and brain tumor treatment involves the merger of science and technology, and we are developing advanced, creative methods that aim to give the upper hand to patients battling malignant brain tumors.
 
These highly complex approaches include gene therapy and immunotherapy – methods that seek to circumvent barriers that hinder effective treatment. We are particularly excited about studies that harness the neural stem cell’s ability to travel to the tumor and bring chemotherapy to the brain, and the use of genetically modified T cells as an immunotherapy strategy to help your immune system fight off the cancer.
 
In addition, our researchers are developing methods of measuring drug levels in the brain to determine which promising chemotherapy agent should be used in brain tumor patients. We are also developing minimally invasive techniques that allow localized removal of brain tumors and delivery of treatments. 
 
Through our research, our ultimate goal is not to simply improve survival rates, but to eradicate the lethal threat of glioblastoma altogether.
 
 

 
 
 

Our Approach

Our Approach - Brain Tumors

As a patient at City of Hope, you have a highly experienced and dedicated team to treat your brain tumor. Whether you have a benign pituitary tumor or an aggressive glioblastoma, we offer a comprehensive, individualized approach to treating brain tumors.
 
Our Brain Tumor Team, including surgeons, medical oncologists and radiation oncologists, creates treatment plans tailored to each patient. Where possible, our surgeons use minimally invasive surgical techniques that minimize injury to the brain and surrounding structure. And our radiation oncologists use state-of-the-art radiation therapy techniques, including Helical TomoTherapy and stereotactic radiosurgery (SRS), which deliver highly localized doses of radiation to primary tumors and metastases while sparing as much normal tissue as possible. 
 
City of Hope researchers are conducting clinical trials of innovative therapies to find more effective treatments for patients with brain tumors. We believe the future of neurosurgery and brain tumor treatment involves the merger of science and technology, and we are developing advanced, creative methods that aim to give the upper hand to patients battling malignant brain tumors.
 
These highly complex approaches include gene therapy and immunotherapy – methods that seek to circumvent barriers that hinder effective treatment. We are particularly excited about studies that harness the neural stem cell’s ability to travel to the tumor and bring chemotherapy to the brain, and the use of genetically modified T cells as an immunotherapy strategy to help your immune system fight off the cancer.
 
In addition, our researchers are developing methods of measuring drug levels in the brain to determine which promising chemotherapy agent should be used in brain tumor patients. We are also developing minimally invasive techniques that allow localized removal of brain tumors and delivery of treatments. 
 
Through our research, our ultimate goal is not to simply improve survival rates, but to eradicate the lethal threat of glioblastoma altogether.
 
 

 
 
 
Quick Links
Featured Videos
Division of Neurosurgery
City of Hope has some of the most advanced tools for the surgical removal of brain and spine tumors. Learn how these tools have enabled surgery of the highest precision while minimizing adverse outcomes.
 
City of Hope’s Division of Neurosurgery focuses on surgical treatment of both benign and malignant brain, spine and pituitary tumors. Our physicians are nationally-recognized experts in neurosurgery and neuro-oncology, and employ today’s leading edge therapies.

For questions or additional information, please call 626-471-7100.
Brain Tumor Medical Minute
Refer a Patient
Physicians can choose a number of options to refer a patient:

 


NEWS & UPDATES
  • Valentine’s Day is synonymous with dinner reservations, red roses, heart-shaped boxes of chocolates and — more often than not — unrealistically high expectations. Managing those expectations is great advice for all couples on Feb. 14 — and is especially important for couples confronting a cancer diagnosis. Focu...
  • With measles, what starts at a theme park in California definitely doesn’t stay at a theme park in California. Since the beginning of the current measles outbreak – traced to an initial exposure at Disneyland or Disney California Adventure during December – more than 100 people have been diagnosed with a diseas...
  • Even the most loving and secure relationship can be rattled by a life-threatening illness. When a woman is diagnosed with breast cancer, research shows one of the most important factors in helping her cope is having a supportive partner. But that partner can struggle with knowing what to say or how to best supp...
  • It’s been more than a century since Nobel Laureate Paul Ehrlich popularized the idea of a “magic bullet” targeting disease. Cancer researchers ever since have remained in hot pursuit of targeted therapies that home in on cancer cells while leaving normal cells unaffected. Linda Malkas, Ph.D., associate chair of...
  • Cancer patients face a daunting journey marked by challenges and uncertainties. For those undergoing bone marrow, or stem cell, transplantation, one complication poses a particular threat — chronic graft-versus-host disease (GVHD). Now, one researcher may have found a better way to control that threat. GVHD res...
  • Michele Dahlstein, a 50-year-old breast cancer survivor from Upland, California, celebrated her last day of chemotherapy on Dec. 30. She shares her story in her own words: I was diagnosed with breast cancer (invasive ductal carcinoma stage 2) on Aug. 11, 2014, after my yearly mammogram at City of Hope’s W...
  • The treatment of urologic cancers, including bladder cancer, is rapidly evolving. Here, urologic oncologic surgeon and kidney stone specialist Donald Hannoun, M.D., an assistant clinical professor in the Division of Urology and Urologic Oncology at City of Hope | Antelope Valley, explains the changes in hi...
  • A woman confronting metastatic breast cancer faces challenges that, at the outset, seem overwhelming. Research tells us these patients are especially vulnerable to anxiety, depression, hopelessness and other sources of distress. At the same time, they are asked to make complicated choices about their medical ca...
  • California health officials are opting to be safe rather than sorry when it comes to e-cigarettes. The increasingly popular devices are a public health threat, according to a California Department of Health report released Jan. 28. The department is seeking statewide regulation of e-cigarettes, saying they  emi...
  • “Not beyond us.” On World Cancer Day, researchers and caregivers around the globe are embracing this refrain. Specifically, the day calls for action to support healthier lifestyles, early cancer detection, quality of life and access to care. In a time of impressive scientific discovery and narrowing...
  • With more advanced cancer treatments and therapies saving lives every day, it’s safe to say cancer is “Not beyond us,” the official tagline for this year’s World Cancer Day. This year’s World Cancer Day observance takes place on Wednesday, Feb. 4, and focuses on cancer prevention, detection an...
  • Does our environment increase our risk of cancer? What about plastic bottles, radiation, chemicals, soy products …? Do they cause cancer? With so many cancer fears, rumors and downright urban legends circulating among our friends and colleagues, not to mention in the media and blogosphere, why not ask the...
  • With this week’s World Cancer Day challenging us to think about cancer on a global scale, we should also keep in mind that daily choices affect cancer risk on an individual scale. Simply put, lifestyle changes and everyday actions can reduce your cancer risk and perhaps prevent some cancers. According to ...
  • If you haven’t heard the term “precision medicine,” you will. If you don’t have an opinion about access to it, you will. On Friday, President Barack Obama unveiled details of the Precision Medicine Initiative, an effort intended to accelerate cancer research in a powerful way, giving doctors new knowledge and n...
  • The lack of a practical way to produce and store enough stem cells for larger-scale therapies and clinical trials is creating a bottleneck in stem cell research. A new grant to City of Hope from the California Institute for Regenerative Medicine (CIRM) will help solve that problem. The $899,728 grant, awarded T...