A National Cancer Institute-designated Comprehensive Cancer Center

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Our Approach - Brain Tumors

As a patient at City of Hope, you have a highly experienced and dedicated team to treat your brain tumor. Whether you have a benign pituitary tumor or an aggressive glioblastoma, we offer a comprehensive, individualized approach to treating brain tumors.
 
Our Brain Tumor Team, including surgeons, medical oncologists and radiation oncologists, creates treatment plans tailored to each patient. Where possible, our surgeons use minimally invasive surgical techniques that minimize injury to the brain and surrounding structure. And our radiation oncologists use state-of-the-art radiation therapy techniques, including Helical TomoTherapy and stereotactic radiosurgery (SRS), which deliver highly localized doses of radiation to primary tumors and metastases while sparing as much normal tissue as possible. 
 
City of Hope researchers are conducting clinical trials of innovative therapies to find more effective treatments for patients with brain tumors. We believe the future of neurosurgery and brain tumor treatment involves the merger of science and technology, and we are developing advanced, creative methods that aim to give the upper hand to patients battling malignant brain tumors.
 
These highly complex approaches include gene therapy and immunotherapy – methods that seek to circumvent barriers that hinder effective treatment. We are particularly excited about studies that harness the neural stem cell’s ability to travel to the tumor and bring chemotherapy to the brain, and the use of genetically modified T cells as an immunotherapy strategy to help your immune system fight off the cancer.
 
In addition, our researchers are developing methods of measuring drug levels in the brain to determine which promising chemotherapy agent should be used in brain tumor patients. We are also developing minimally invasive techniques that allow localized removal of brain tumors and delivery of treatments. 
 
Through our research, our ultimate goal is not to simply improve survival rates, but to eradicate the lethal threat of glioblastoma altogether.
 
 

 
 
 

Our Approach

Our Approach - Brain Tumors

As a patient at City of Hope, you have a highly experienced and dedicated team to treat your brain tumor. Whether you have a benign pituitary tumor or an aggressive glioblastoma, we offer a comprehensive, individualized approach to treating brain tumors.
 
Our Brain Tumor Team, including surgeons, medical oncologists and radiation oncologists, creates treatment plans tailored to each patient. Where possible, our surgeons use minimally invasive surgical techniques that minimize injury to the brain and surrounding structure. And our radiation oncologists use state-of-the-art radiation therapy techniques, including Helical TomoTherapy and stereotactic radiosurgery (SRS), which deliver highly localized doses of radiation to primary tumors and metastases while sparing as much normal tissue as possible. 
 
City of Hope researchers are conducting clinical trials of innovative therapies to find more effective treatments for patients with brain tumors. We believe the future of neurosurgery and brain tumor treatment involves the merger of science and technology, and we are developing advanced, creative methods that aim to give the upper hand to patients battling malignant brain tumors.
 
These highly complex approaches include gene therapy and immunotherapy – methods that seek to circumvent barriers that hinder effective treatment. We are particularly excited about studies that harness the neural stem cell’s ability to travel to the tumor and bring chemotherapy to the brain, and the use of genetically modified T cells as an immunotherapy strategy to help your immune system fight off the cancer.
 
In addition, our researchers are developing methods of measuring drug levels in the brain to determine which promising chemotherapy agent should be used in brain tumor patients. We are also developing minimally invasive techniques that allow localized removal of brain tumors and delivery of treatments. 
 
Through our research, our ultimate goal is not to simply improve survival rates, but to eradicate the lethal threat of glioblastoma altogether.
 
 

 
 
 
Quick Links
Refer a Patient
Physicians can choose a number of options to refer a patient:

  • Call 800-826-HOPE (4673) to speak with a patient referral specialist.
  • Fax the patient face sheet to 626-301-8432
  • Complete an online callback request form
 
Featured Videos
Brain Tumor Medical Minute
Division of Neurosurgery
City of Hope has some of the most advanced tools for the surgical removal of brain and spine tumors. Learn how these tools have enabled surgery of the highest precision while minimizing adverse outcomes.
 
City of Hope’s Division of Neurosurgery focuses on surgical treatment of both benign and malignant brain, spine and pituitary tumors. Our physicians are nationally-recognized experts in neurosurgery and neuro-oncology, and employ today’s leading edge therapies.

For questions or additional information, please call 626-471-7100.
NEWS & UPDATES
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  • Rob Darakjian was diagnosed with acute lymphoblastic leukemia at just 19 years old. He began chemotherapy and was in and out of the hospital for four months. After his fourth round of treatment, he received a bone marrow transplantation from an anonymous donor. Today, he’s cancer free. In his first post, ...
  • Advanced age tops the list among breast cancer risk factor for women. Not far behind is family history and genetics. Two City of Hope researchers delving deep into these issues recently received important grants to advance their studies. Arti Hurria, M.D., director of the Cancer and Aging Research Program, and ...
  • City of Hope is extending the reach of its lifesaving mission well beyond U.S. borders. To that end, three distinguished City of Hope leaders visited China earlier this year to lay the foundation for the institution’s new International Medicine Program. The program is part of City of Hope’s strategi...
  • A hallmark of cancer is that it doesn’t always limit itself to a primary location. It spreads. Breast cancer and lung cancer in particular are prone to spread, or metastasize, to the brain. Often the brain metastasis isn’t discovered until years after the initial diagnosis, just when patients were beginning to ...
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  • Most women who are treated for breast cancer with a mastectomy do not choose to undergo reconstructive surgery. The reasons for this, according to a recent JAMA Surgery study, vary. Nearly half say they do not want any additional surgery, while nearly 34 percent say breast cancer reconstruction simply isn’t imp...
  • The leading risk factor for breast cancer is simply being a woman. The second top risk factor is getting older. Obviously, these two factors cannot be controlled, which is why all women should be aware of their risk and how to minimize those risks. Many risk factors can be mitigated, and simple changes can lead...
  • All women are at some risk of developing the disease in their lifetimes, but breast cancer, like other cancers, has a disproportionate effect on minorities. Although white women have the highest incidence of breast cancer, African-American women have the highest breast cancer death rates of all racial and ethni...
  • First, the good news: HIV infections have dropped dramatically over the past 30 years. Doctors, researchers and health officials have made great strides in preventing and treating the disease, turning what was once a death sentence into, for some, a chronic condition. Now, the reality check: HIV is still a worl...
  • Screening for breast cancer has dramatically increased the number of cancers found before they cause symptoms – catching the disease when it is most treatable and curable. Mammograms, however, are not infallible. It’s important to conduct self-exams, and know the signs and symptoms that should be checked by a h...
  • Rob Darakjian was diagnosed with acute lymphoblastic leukemia at just 19 years old. He began chemotherapy and was in and out of the hospital for four months. After his fourth round of treatment, he received a bone marrow transplantation from an anonymous donor. Today, he’s cancer free.   In his previ...
  • In a single day, former professional triathlete Lisa Birk learned she couldn’t have children and that she had breast cancer. “Where do you go from there?” she asks. For Birk, who swims three miles, runs 10 miles and cycles every day, the answer  ultimately was a decision to take control of her cancer care. Afte...
  • More and more people are surviving cancer, thanks to advanced cancer treatments and screening tools. Today there are nearly 14.5 million cancer survivors in the United States. But in up to 20 percent of cancer patients, the disease ultimately spreads to their brain. Each year, nearly 170,000 new cases of brain ...