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Our Approach - Brain Tumors

As a patient at City of Hope, you have a highly experienced and dedicated team to treat your brain tumor. Whether you have a benign pituitary tumor or an aggressive glioblastoma, we offer a comprehensive, individualized approach to treating brain tumors.
 
Our Brain Tumor Team, including surgeons, medical oncologists and radiation oncologists, creates treatment plans tailored to each patient. Where possible, our surgeons use minimally invasive surgical techniques that minimize injury to the brain and surrounding structure. And our radiation oncologists use state-of-the-art radiation therapy techniques, including Helical TomoTherapy and stereotactic radiosurgery (SRS), which deliver highly localized doses of radiation to primary tumors and metastases while sparing as much normal tissue as possible. 
 
City of Hope researchers are conducting clinical trials of innovative therapies to find more effective treatments for patients with brain tumors. We believe the future of neurosurgery and brain tumor treatment involves the merger of science and technology, and we are developing advanced, creative methods that aim to give the upper hand to patients battling malignant brain tumors.
 
These highly complex approaches include gene therapy and immunotherapy – methods that seek to circumvent barriers that hinder effective treatment. We are particularly excited about studies that harness the neural stem cell’s ability to travel to the tumor and bring chemotherapy to the brain, and the use of genetically modified T cells as an immunotherapy strategy to help your immune system fight off the cancer.
 
In addition, our researchers are developing methods of measuring drug levels in the brain to determine which promising chemotherapy agent should be used in brain tumor patients. We are also developing minimally invasive techniques that allow localized removal of brain tumors and delivery of treatments. 
 
Through our research, our ultimate goal is not to simply improve survival rates, but to eradicate the lethal threat of glioblastoma altogether.
 
 

 
 
 

Our Approach

Our Approach - Brain Tumors

As a patient at City of Hope, you have a highly experienced and dedicated team to treat your brain tumor. Whether you have a benign pituitary tumor or an aggressive glioblastoma, we offer a comprehensive, individualized approach to treating brain tumors.
 
Our Brain Tumor Team, including surgeons, medical oncologists and radiation oncologists, creates treatment plans tailored to each patient. Where possible, our surgeons use minimally invasive surgical techniques that minimize injury to the brain and surrounding structure. And our radiation oncologists use state-of-the-art radiation therapy techniques, including Helical TomoTherapy and stereotactic radiosurgery (SRS), which deliver highly localized doses of radiation to primary tumors and metastases while sparing as much normal tissue as possible. 
 
City of Hope researchers are conducting clinical trials of innovative therapies to find more effective treatments for patients with brain tumors. We believe the future of neurosurgery and brain tumor treatment involves the merger of science and technology, and we are developing advanced, creative methods that aim to give the upper hand to patients battling malignant brain tumors.
 
These highly complex approaches include gene therapy and immunotherapy – methods that seek to circumvent barriers that hinder effective treatment. We are particularly excited about studies that harness the neural stem cell’s ability to travel to the tumor and bring chemotherapy to the brain, and the use of genetically modified T cells as an immunotherapy strategy to help your immune system fight off the cancer.
 
In addition, our researchers are developing methods of measuring drug levels in the brain to determine which promising chemotherapy agent should be used in brain tumor patients. We are also developing minimally invasive techniques that allow localized removal of brain tumors and delivery of treatments. 
 
Through our research, our ultimate goal is not to simply improve survival rates, but to eradicate the lethal threat of glioblastoma altogether.
 
 

 
 
 
Quick Links
Featured Videos
Division of Neurosurgery
City of Hope has some of the most advanced tools for the surgical removal of brain and spine tumors. Learn how these tools have enabled surgery of the highest precision while minimizing adverse outcomes.
 
City of Hope’s Division of Neurosurgery focuses on surgical treatment of both benign and malignant brain, spine and pituitary tumors. Our physicians are nationally-recognized experts in neurosurgery and neuro-oncology, and employ today’s leading edge therapies.

For questions or additional information, please call 626-471-7100.
Brain Tumor Medical Minute
Refer a Patient
Physicians can choose a number of options to refer a patient:

 


NEWS & UPDATES
  • The lack of a practical way to produce and store enough stem cells for larger-scale therapies and clinical trials is creating a bottleneck in stem cell research. A new grant to City of Hope from the California Institute for Regenerative Medicine will help solve that problem. The $899,728 grant, awarded Thursday...
  • City of Hope has long known what researchers increasingly are confirming: Gardens and natural surroundings help seriously ill people recover from their treatment ordeals. Already a trailblazer in the creation of beautiful natural spaces for cancer patients and their families, on Jan. 15,  City of Hope dedicated...
  • Despite advances in surgery, radiation and drug therapy, brain tumors remain particularly challenging to treat. This is due to the tumor’s location, which can limit localized therapies’ effectiveness, and the blood-brain barrier, which blocks many cancer-fighting drugs’ passage from the bloodstream to the tumor...
  • We’ve seen it in science fiction: The aliens begin terra-forming a planet to create a friendly habitat that gives them, not the inhabitants, all the advantages when the colonization begins. Turns out, cancer does essentially the same thing when it metastasizes, according to new research from City of Hope. The f...
  • Equipping the immune system to fight cancer – a disease that thrives on mutations and circumventing the body’s natural defenses – is within reach. In fact, City of Hope researchers are testing one approach in clinical trials now. Scientists take a number of steps to turn cancer patients’ T cells – white b...
  • As treatments for lung cancer become more targeted and effective, the need for better technology to detect lung cancer mutations becomes increasingly important. A new clinical study at City of Hope is examining the feasibility of using blood and urine tests to detect lung cancer mutations, potentially allowing ...
  • When it comes to breast cancer risk, insulin levels may matter more than weight, new research has found. The study from Imperial College London School of Public Health, published in the journal Cancer Research, indicates that metabolic health – not a person’s weight or body mass index – increases breast cancer ...
  • No one ever plans to have cancer – and there’s never a good time. For Homa Sadat, her cancer came at a particularly bad time: just one year after losing her father to the pancreatic cancer he had battled for two years. She was working a grueling schedule managing three commercial office buildings. She’d just [&...
  • Patients at City of Hope – most of whom are fighting cancer – rely on more than 37,000 units of blood and platelets each year for their treatment and survival. Every one of those units comes from family, friends or someone who traded an hour or so of their time and a pint of their […]
  • Surgery is vital in the treatment of cancer – it’s used to help diagnose, treat and even prevent the disease – so a new colorectal cancer study linking a decrease in surgeries for advanced cancer to increased survival rates may raise more questions than it answers for some patients. The surgery-and-surviv...
  • Age is the single greatest risk factor overall for cancer; our chances of developing the disease rise steeply after age 50. For geriatric oncology nurse Peggy Burhenn, the meaning is clear: Cancer is primarily a geriatric condition. That’s why she is forging inroads in the care of older adults with cancer. Burh...
  • One of American’s great sportscasters, Stuart Scott, passed away from recurrent cancer of the appendix at the young age of 49. His cancer was diagnosed when he was only 40 years old. It was found during an operation for appendicitis. His courageous fight against this disease began in 2007, resumed again with an...
  • When Homa Sadat found a lump in her breast at age 27, her gynecologist told her what many doctors say to young women: You’re too young to have breast cancer. With the lump dismissed as a harmless cyst, she didn’t think about it again until she was at a restaurant six months later and felt […]
  • What most people call a “bone marrow transplant” is not actually a transplant of bone marrow; it is instead the transplantation of what’s known as hematopoietic stem cells. Such cells are often taken from bone marrow, but not always. Hematopoietic stem cells are simply immature cells that can ...
  • Doctors have long known that women with a precancerous condition called atypical hyperplasia have an elevated risk of breast cancer. Now a new study has found that the risk is more serious than previously thought. Hyperplasia itself is an overgrowth of cells; atypical hyperplasia is an overgrowth in a distorted...