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Division of Biostatistics

The Division of Biostatistics provides statistical expertise for basic, translational, and clinical research.
 
The services provided by the Division of Biostatistics are collaboration, consulting, and statistical computing. The core faculty members maintain expertise in a variety of specialized areas including clinical trials, high throughput functional genomics, pharmacokinetic modeling, epidemiology and statistical genetics.
 
The Division of Biostatistics assists Cancer Center and Beckman Research Institute investigators with study design, analytic plan development, database design and data extraction, efficacy and safety monitoring, manuscript preparation, and the development of grant proposals and clinical protocols. Service to the institution includes statistical review of cancer-related clinical research protocols for the CPRMC, IRB and DSMB. Outside of their core activities, the faculty members are also engaged in externally funded biomedical research, the development of statistical methodology and teaching in the graduate school and the Clinical Investigation Training Program.

The Biostatistics Core is directed by Dr. Jeffrey Longmate, Director of the Division of Biostatistics, with Dr. David D. Smith serving as co-director. The Biostatistics Core draws effort from a large part of the Division of Biostatistics, with the Biostatistics Core enabling their participation in Cancer Center-related pilot projects and proposals, which may later develop into externally funded projects. The Biostatistics Core is directly involved in Cancer Center research from the inception of a research idea to the publication of results. Clinical research projects account for the largest portion of core use, but the Biostatistics Core also supports basic and translational research, as well as assisting several other cores. The Biostatistics Core staff collaborate closely with the Biomedical Informatics core to support data processing and analysis of gene expression microarrays, and the Biostatistics Core works closely with both the Clinical Research Informatics Core and the Clinical Trials Management Core to implement City of Hope-conducted or coordinated clinical protocols. In addition to these ongoing collaborative efforts, there have been more technically-focused projects in which the Biostatistics Core has supported the other cores in the implementation of technologies that involve statistical measurement issues. This has recently included the Affymetrix Core, the Clinical Immunobiology Correlative Studies Lab, and the Genotyping Core.
 
 
  • Joyce Niland’s research interests are clinical trials methodology, outcomes research, and biomedical informatics. She also directs the Data Coordinating Centers for two nationwide research networks: (1) the National Comprehensive Cancer Network (NCCN) Outcomes Research Study, studying patterns of care, guideline concordance, and factors associated with patient outcomes within our nation’s Cancer Centers; and (2) the Islet Cell Resources (ICR) consortium, investigating optimization of islet cell harvesting for transplantation in type I diabetes.
  • Jeffrey Longmate’s research interests are study design and statistical inference arising from collaborations in genetics, immunology, and early-phase clinical trials. Dr. Longmate co-directs the coordinating center for multi-center Phase I/II drug development, directs the Data Coordinating Center for the Southern California Islet-Cell Consortium, and coordinates the Biostatistics segment of the Biostatistics and Bioinformatics course for the Graduate School and the Medical Fellows Training Program.
  • Li Cheng’s research interests include the role of genetic markers and receptors in the etiology and manifestation of disease processes.
  • David Smith is interested in pre-clinical study design, clinical trial methodology, and microarray study design and data analysis.
  • Paul Frankel’s research interests include clinical trials methodology and survival analysis techniques.
  • Rebecca Nelson’s research interests include exploring patterns of disease risk and outcomes as related to clinical and environmental covariates.
  • Dajun Qian’s research interests include clinical trial methodology, linkage analysis, and haplotype sharing correlation analysis.
  • Rebecca Ottesen
  • Joycelynne Palmer
  • Nora Ruel
  • Carolyn Behrendt
  • Suzette M. Blanchard
  • Min Sierra Li
  • Xueli Liu
  • F. Lennie Wong
  • Andy Dagis
  • Julie Kilburn
  • Arthur Li
  • Christopher Ruel
  • Tracey Stiller
  • Leanne Streja
  • Nicole Tsai
  • Wei Ye
 
 
 
 

Biostatistics Faculty, Heads, and Biostatisticians

The Division encourages collaboration, so investigators are free to contact faculty statisticians directly.  Investigators can request an introduction or consulting appointment by phone or email:
 
City of Hope and Beckman Research Institute
1500 East Duarte Road
Duarte, CA  91010-3000
 
Information Sciences Building (#171)
Phone:  626-256-HOPE (4673), ext. 61444
Fax:  626-471-7106 or 626-301-8802
 
Investigators are encouraged to consult with a statistician early in their planning.
 

Biostatistics

Division of Biostatistics

The Division of Biostatistics provides statistical expertise for basic, translational, and clinical research.
 
The services provided by the Division of Biostatistics are collaboration, consulting, and statistical computing. The core faculty members maintain expertise in a variety of specialized areas including clinical trials, high throughput functional genomics, pharmacokinetic modeling, epidemiology and statistical genetics.
 
The Division of Biostatistics assists Cancer Center and Beckman Research Institute investigators with study design, analytic plan development, database design and data extraction, efficacy and safety monitoring, manuscript preparation, and the development of grant proposals and clinical protocols. Service to the institution includes statistical review of cancer-related clinical research protocols for the CPRMC, IRB and DSMB. Outside of their core activities, the faculty members are also engaged in externally funded biomedical research, the development of statistical methodology and teaching in the graduate school and the Clinical Investigation Training Program.

The Biostatistics Core is directed by Dr. Jeffrey Longmate, Director of the Division of Biostatistics, with Dr. David D. Smith serving as co-director. The Biostatistics Core draws effort from a large part of the Division of Biostatistics, with the Biostatistics Core enabling their participation in Cancer Center-related pilot projects and proposals, which may later develop into externally funded projects. The Biostatistics Core is directly involved in Cancer Center research from the inception of a research idea to the publication of results. Clinical research projects account for the largest portion of core use, but the Biostatistics Core also supports basic and translational research, as well as assisting several other cores. The Biostatistics Core staff collaborate closely with the Biomedical Informatics core to support data processing and analysis of gene expression microarrays, and the Biostatistics Core works closely with both the Clinical Research Informatics Core and the Clinical Trials Management Core to implement City of Hope-conducted or coordinated clinical protocols. In addition to these ongoing collaborative efforts, there have been more technically-focused projects in which the Biostatistics Core has supported the other cores in the implementation of technologies that involve statistical measurement issues. This has recently included the Affymetrix Core, the Clinical Immunobiology Correlative Studies Lab, and the Genotyping Core.
 
 
  • Joyce Niland’s research interests are clinical trials methodology, outcomes research, and biomedical informatics. She also directs the Data Coordinating Centers for two nationwide research networks: (1) the National Comprehensive Cancer Network (NCCN) Outcomes Research Study, studying patterns of care, guideline concordance, and factors associated with patient outcomes within our nation’s Cancer Centers; and (2) the Islet Cell Resources (ICR) consortium, investigating optimization of islet cell harvesting for transplantation in type I diabetes.
  • Jeffrey Longmate’s research interests are study design and statistical inference arising from collaborations in genetics, immunology, and early-phase clinical trials. Dr. Longmate co-directs the coordinating center for multi-center Phase I/II drug development, directs the Data Coordinating Center for the Southern California Islet-Cell Consortium, and coordinates the Biostatistics segment of the Biostatistics and Bioinformatics course for the Graduate School and the Medical Fellows Training Program.
  • Li Cheng’s research interests include the role of genetic markers and receptors in the etiology and manifestation of disease processes.
  • David Smith is interested in pre-clinical study design, clinical trial methodology, and microarray study design and data analysis.
  • Paul Frankel’s research interests include clinical trials methodology and survival analysis techniques.
  • Rebecca Nelson’s research interests include exploring patterns of disease risk and outcomes as related to clinical and environmental covariates.
  • Dajun Qian’s research interests include clinical trial methodology, linkage analysis, and haplotype sharing correlation analysis.
  • Rebecca Ottesen
  • Joycelynne Palmer
  • Nora Ruel
  • Carolyn Behrendt
  • Suzette M. Blanchard
  • Min Sierra Li
  • Xueli Liu
  • F. Lennie Wong
  • Andy Dagis
  • Julie Kilburn
  • Arthur Li
  • Christopher Ruel
  • Tracey Stiller
  • Leanne Streja
  • Nicole Tsai
  • Wei Ye
 
 
 
 

Section Heads, Faculty and Biostatisticians

Biostatistics Faculty, Heads, and Biostatisticians

The Division encourages collaboration, so investigators are free to contact faculty statisticians directly.  Investigators can request an introduction or consulting appointment by phone or email:
 
City of Hope and Beckman Research Institute
1500 East Duarte Road
Duarte, CA  91010-3000
 
Information Sciences Building (#171)
Phone:  626-256-HOPE (4673), ext. 61444
Fax:  626-471-7106 or 626-301-8802
 
Investigators are encouraged to consult with a statistician early in their planning.
 
Research Departments/Divisions

City of Hope is a leader in translational research - integrating basic science, clinical research and patient care.
 

Research Shared Services

City of Hope embodies the spirit of scientific collaboration by sharing services and core facilities with colleagues here and around the world.
 

Our Scientists

Our research laboratories are led by the best and brightest minds in scientific research.
 

City of Hope’s Irell & Manella Graduate School of Biological Sciences equips students with the skills and strategies to transform the future of modern medicine.
Learn more about City of Hope's institutional distinctions, breakthrough innovations and collaborations.
Support Our Research
By giving to City of Hope, you support breakthrough discoveries in laboratory research that translate into lifesaving treatments for patients with cancer and other serious diseases.
 
 
 
 


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